Palladium-catalyzed cross-coupling reactions of chloropyrazines with aromatic heterocycles

In the presence of tetrakis(triphenylphosphine) palladium, chloropyrazines were treated with aromatic heterocycles such as furan, thiophene, pyrrole, N-substituted pyrroles, benzo[b]furan, benzo[b]thiophene, oxazole, thiazole, N-methylimidazoles, benz[b]oxazole and benzo[b]thiazole. The corresponding coupling products were obtained in moderate to good yields. The structures of the coupling products were determined