Effects of Dipeptidyl Peptidase-4 Inhibition with MK-0431 on Syngeneic Mouse Islet Transplantation, Jyuhn-Huarng

[1]  P. Marchetti Islet inflammation in type 2 diabetes , 2016, Diabetologia.

[2]  M. Levy,et al.  Alleviation of Instant Blood-Mediated Inflammatory Reaction in Autologous Conditions Through Treatment of Human Islets with NF-&kgr;B Inhibitors , 2014, Transplantation.

[3]  Hongguang Sheng,et al.  Quantitative Assessment of the Effect of KCNJ11 Gene Polymorphism on the Risk of Type 2 Diabetes , 2014, PloS one.

[4]  A. Dennison,et al.  Evation of High-Mobility Group Box 1 after Clinical Autologous Islet Transplantation and Its Inverse Correlation with Outcomes , 2014, Cell transplantation.

[5]  S. Iwahashi,et al.  Evidence for Instant Blood‐Mediated Inflammatory Reaction in Clinical Autologous Islet Transplantation , 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[6]  M. Rickels,et al.  Improvement in β-Cell Secretory Capacity After Human Islet Transplantation According to the CIT07 Protocol , 2013, Diabetes.

[7]  C. Doglioni,et al.  Autologous Pancreatic Islet Transplantation in Human Bone Marrow , 2013, Diabetes.

[8]  Ping Liu,et al.  The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway , 2013, Peptides.

[9]  M. Levy,et al.  Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation , 2013, Diabetologia.

[10]  E. Bonifacio,et al.  CXCR1/2 inhibition enhances pancreatic islet survival after transplantation. , 2012, The Journal of clinical investigation.

[11]  G. Crabtree,et al.  Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT. , 2012, Developmental cell.

[12]  M. Levy,et al.  Correlation of Released HMGB1 Levels with the Degree of Islet Damage in Mice and Humans and with the Outcomes of Islet Transplantation in Mice , 2012, Cell transplantation.

[13]  A. Shapiro,et al.  Update on islet transplantation. , 2012, Cold Spring Harbor perspectives in medicine.

[14]  P. Meda The In Vivo β-to-β-Cell Chat Room: Connexin Connections Matter , 2012, Diabetes.

[15]  Nicole A. Turgeon,et al.  Improvement in Outcomes of Clinical Islet Transplantation: 1999–2010 , 2012, Diabetes Care.

[16]  B. Hering,et al.  Potent Induction Immunotherapy Promotes Long‐Term Insulin Independence After Islet Transplantation in Type 1 Diabetes , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[17]  Hyo Sung Lee,et al.  E23K polymorphism of the KCNJ11 gene in Korean children with type 1 diabetes , 2012, World Journal of Pediatrics.

[18]  N. Kobayashi,et al.  Fresh Islets are more Effective for Islet Transplantation than Cultured Islets , 2012, Cell transplantation.

[19]  G. J. Santos,et al.  Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance , 2012, Diabetologia.

[20]  A. Shapiro,et al.  Anakinra Potentiates the Protective Effects of Etanercept in Transplantation of Marginal Mass Human Islets in Immunodeficient Mice , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[21]  Y. Makino,et al.  Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice , 2012, Diabetologia.

[22]  R. Sladek,et al.  Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture , 2012, PloS one.

[23]  S. Gandhi,et al.  A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats. , 2012, Biochemical pharmacology.

[24]  Mi-kyung Kim,et al.  DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes. , 2012, Life sciences.

[25]  T. Kuroki,et al.  The effect of selective neutrophil elastase inhibitor on pancreatic islet yields and functions in rat with hypercytokinemia. , 2011, Annals of transplantation.

[26]  P. Halban,et al.  Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion* , 2011, The Journal of Biological Chemistry.

[27]  B. Nilsson,et al.  Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment , 2011, Current opinion in organ transplantation.

[28]  Ji‐Won Kim,et al.  Both sitagliptin analogue & pioglitazone preserve the beta-cell proportion in the islets with different mechanism in non-obese and obese diabetic mice. , 2011, BMB reports.

[29]  D. Chaussabel,et al.  Improving Efficacy of Clinical Islet Transplantation with Iodixanol-Based Islet Purification, Thymoglobulin Induction, and Blockage of IL-1β and TNF-α , 2011, Cell transplantation.

[30]  Preeti Chhabra,et al.  Current Status of Immunomodulatory and Cellular Therapies in Preclinical and Clinical Islet Transplantation , 2011, Journal of transplantation.

[31]  G. J. Santos,et al.  CNTF protects MIN6 cells against apoptosis induced by Alloxan and IL-1β through downregulation of the AMPK pathway. , 2011, Cellular Signalling.

[32]  A. Shapiro,et al.  State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression , 2011, Current diabetes reports.

[33]  Sang-Man Jin,et al.  The Sequential Combination of a JNK Inhibitor and Simvastatin Protects Porcine Islets from Peritransplant Apoptosis and Inflammation , 2011, Cell transplantation.

[34]  A. Boschero,et al.  Morphofunctional alterations in endocrine pancreas of short- and long-term dexamethasone-treated rats. , 2011, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[35]  H. Okada,et al.  Attenuation of Cross-Talk Between the Complement and Coagulation Cascades by C5a Blockade Improves Early Outcomes After Intraportal Islet Transplantation , 2010, Transplantation.

[36]  H. Iwata,et al.  Immobilization of the soluble domain of human complement receptor 1 on agarose-encapsulated islets for the prevention of complement activation. , 2010, Biomaterials.

[37]  M. Levy,et al.  Calcineurin/Nuclear Factor of Activated T Cells and MAPK Signaling Induce TNF-α Gene Expression in Pancreatic Islet Endocrine Cells* , 2010, The Journal of Biological Chemistry.

[38]  S. Taboga,et al.  The adaptive compensations in endocrine pancreas from glucocorticoid‐treated rats are reversible after the interruption of treatment , 2010, Acta physiologica.

[39]  Hua Yang,et al.  Diannexin Decreases Inflammatory Cell Infiltration Into the Islet Graft, Reduces &bgr;-Cell Apoptosis, and Improves Early Graft Function , 2010, Transplantation.

[40]  E. Bonifacio,et al.  Role of CCL2/MCP-1 in Islet Transplantation , 2010, Cell transplantation.

[41]  M. Rickels,et al.  HLA Class I Sensitization in Islet Transplant Recipients: Report from the Collaborative Islet Transplant Registry 1 , 2010, Cell transplantation.

[42]  D. Scharp,et al.  Islet isolation from human pancreas with extended cold ischemia time. , 2010, Transplantation proceedings.

[43]  H. Okada,et al.  C5a-inhibitory peptide combined with gabexate mesilate prevents the instant blood-mediated inflammatory reaction in a rat model of islet transplantation. , 2010, Transplantation proceedings.

[44]  N. Kobayashi,et al.  Comparison of fresh and cultured islets from human and porcine pancreata. , 2010, Transplantation proceedings.

[45]  M. Cobb,et al.  Regulation of CCAAT/Enhancer-binding Protein Homologous Protein (CHOP) Expression by Interleukin-1β in Pancreatic β Cells* , 2010, The Journal of Biological Chemistry.

[46]  R. Heine,et al.  Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men. , 2010, European journal of endocrinology.

[47]  Hiroshi Yamamoto,et al.  High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice. , 2010, The Journal of clinical investigation.

[48]  G. Fontés,et al.  Glucolipotoxicity of the pancreatic beta cell. , 2010, Biochimica et biophysica acta.

[49]  P. J. Larsen,et al.  Characterization of β‐Cell Mass and Insulin Resistance in Diet‐induced Obese and Diet‐resistant Rats , 2010, Obesity.

[50]  M. Cobb,et al.  Multiple chromatin-bound protein kinases assemble factors that regulate insulin gene transcription , 2009, Proceedings of the National Academy of Sciences.

[51]  A Sundin,et al.  Positron Emission Tomography in Clinical Islet Transplantation , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[52]  Tanya Hansotia,et al.  Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice. , 2009, Gastroenterology.

[53]  E. Bonifacio,et al.  Bone marrow as an alternative site for islet transplantation. , 2009, Blood.

[54]  H. Münzberg,et al.  Critical roles for the TSC-mTOR pathway in β-cell function. , 2009, American journal of physiology. Endocrinology and metabolism.

[55]  N. Kenyon,et al.  Immune Cell Populations in Nonhuman Primate Islets , 2009, Cell transplantation.

[56]  C. Mcintosh,et al.  Suppression of p38 MAPK and JNK via Akt-mediated Inhibition of Apoptosis Signal-regulating Kinase 1 Constitutes a Core Component of the β-Cell Pro-survival Effects of Glucose-dependent Insulinotropic Polypeptide* , 2009, The Journal of Biological Chemistry.

[57]  S. Taboga,et al.  High doses of dexamethasone induce increased beta-cell proliferation in pancreatic rat islets. , 2009, American journal of physiology. Endocrinology and metabolism.

[58]  H. Thomas,et al.  Beta cell apoptosis in diabetes , 2009, Apoptosis.

[59]  M. Karin,et al.  Regulation and function of NF-kappaB transcription factors in the immune system. , 2009, Annual review of immunology.

[60]  E. Mayer-Davis,et al.  The Many Faces of Diabetes in American Youth: Type 1 and Type 2 Diabetes in Five Race and Ethnic Populations: The SEARCH for Diabetes in Youth Study , 2009, Diabetes Care.

[61]  J. Connolly,et al.  Evidence for Induced Expression of HLA Class II on Human Islets: Possible Mechanism for HLA Sensitization in Transplant Recipients , 2009, Transplantation.

[62]  B. Hering,et al.  Effect of short‐term culture on functional and stress‐related parameters in isolated human islets , 2009, Transplant international : official journal of the European Society for Organ Transplantation.

[63]  M. Rashid,et al.  The Effect of Composite Pig Islet-Human Endothelial Cell Grafts on the Instant Blood-Mediated Inflammatory Reaction , 2009, Cell transplantation.

[64]  C. Ricordi,et al.  Islet Transplantation with Alemtuzumab Induction and Calcineurin-Free Maintenance Immunosuppression Results in Improved Short- and Long-Term Outcomes , 2008, Transplantation.

[65]  G. Beilman,et al.  Islet Autotransplant Outcomes After Total Pancreatectomy: A Contrast to Islet Allograft Outcomes , 2008, Transplantation.

[66]  P. Leung,et al.  Combination of the Dipeptidyl Peptidase IV Inhibitor LAF237 [(S)-1-[(3-Hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the Angiotensin II Type 1 Receptor Antagonist Valsartan [N-(1-Oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl]methyl]-l-valine] Enhances Pancreatic Islet Morpholo , 2008, Journal of Pharmacology and Experimental Therapeutics.

[67]  B. Hering,et al.  Prolonged Insulin Independence After Islet Allotransplants in Recipients with Type 1 Diabetes , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[68]  M. Pasparakis IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut , 2008, Mucosal Immunology.

[69]  J. Hartwig,et al.  GLUT4 Vesicle Recruitment and Fusion Are Differentially Regulated by Rac, AS160, and Rab8A in Muscle Cells* , 2008, Journal of Biological Chemistry.

[70]  M. Cobb,et al.  Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in β-cells , 2008, Proceedings of the National Academy of Sciences.

[71]  C. Taylor Interdependent roles for hypoxia inducible factor and nuclear factor‐κB in hypoxic inflammation , 2008, The Journal of physiology.

[72]  S. Taboga,et al.  Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate‐2/serine‐threonine kinase pathway and augmented cyclin D2 protein levels in insulin‐resistant rats , 2008, International journal of experimental pathology.

[73]  K. Sakamoto,et al.  Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. , 2008, American journal of physiology. Endocrinology and metabolism.

[74]  John D Lambris,et al.  Dissecting the instant blood‐mediated inflammatory reaction in islet xenotransplantation , 2008, Xenotransplantation.

[75]  Charity Juang,et al.  Exendin-4 Treatment Expands Graft β-Cell Mass in Diabetic Mice Transplanted with a Marginal Number of Fresh Islets , 2008, Cell transplantation.

[76]  E. Benedetti,et al.  Islet Transplantation for Brittle Type 1 Diabetes: The UIC Protocol , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[77]  J. Kellum,et al.  Increased plasma interleukin-6 in donors is associated with lower recipient hospital-free survival after cadaveric organ transplantation* , 2008, Critical care medicine.

[78]  Qin Wang,et al.  Requirements of calcium fluxes and ERK kinase activation for glucose- and interleukin-1β-induced β-cell apoptosis , 2008, Molecular and Cellular Biochemistry.

[79]  P. Halban,et al.  Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells , 2008, Diabetes.

[80]  D. Doudet,et al.  Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice , 2008, Diabetes.

[81]  O. Schmitz,et al.  Insulin alters cytokine content in two pivotal organs after brain death: a porcine model , 2008, Acta anaesthesiologica Scandinavica.

[82]  K. Ekdahl,et al.  Acute Antibody-Mediated Complement Activation Mediates Lysis of Pancreatic Islets Cells and May Cause Tissue Loss in Clinical Islet Transplantation , 2008, Transplantation.

[83]  A. Boschero,et al.  Functional Alterations in Endocrine Pancreas of Rats With Different Degrees of Dexamethasone-Induced Insulin Resistance , 2008, Pancreas.

[84]  S. Messinger,et al.  Improved Metabolic Control and Quality of Life in Seven Patients With Type 1 Diabetes Following Islet After Kidney Transplantation , 2008, Transplantation.

[85]  D. Drucker,et al.  Exendin-4 modulates diabetes onset in nonobese diabetic mice. , 2008, Endocrinology.

[86]  A. Pocai,et al.  Free fatty acids as mediators of adaptive compensatory responses to insulin resistance in dexamethasone‐treated rats , 2008, Diabetes/metabolism research and reviews.

[87]  D. Drucker,et al.  Differential Antidiabetic Efficacy of Incretin Agonists Versus DPP-4 Inhibition in High Fat–Fed Mice , 2008, Diabetes.

[88]  Eric S. Fowler,et al.  Pathophysiology of chronic pancreatitis. , 2007, The Surgical clinics of North America.

[89]  A. Hattersley,et al.  Genetics and type 2 diabetes in youth , 2007, Pediatric diabetes.

[90]  M. Kubo,et al.  Impact of Kir6.2 E23K Polymorphism on the Development of Type 2 Diabetes in a General Japanese Population , 2007, Diabetes.

[91]  G. Semenza,et al.  Life with Oxygen , 2007, Science.

[92]  H. Shiota,et al.  SNPs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in the Japanese population , 2007, Journal of Human Genetics.

[93]  T. Frayling Genome–wide association studies provide new insights into type 2 diabetes aetiology , 2007, Nature Reviews Genetics.

[94]  R. Larsson,et al.  Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation , 2007, Diabetes.

[95]  S. Taboga,et al.  Dexamethasone-induced insulin resistance is associated with increased connexin 36 mRNA and protein expression in pancreatic rat islets. , 2007, Canadian journal of physiology and pharmacology.

[96]  Dana Dabelea,et al.  Incidence of diabetes in youth in the United States. , 2007, JAMA.

[97]  E. Oetjen,et al.  Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1β and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells , 2007, Diabetologia.

[98]  Marcia M. Nizzari,et al.  Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels , 2007, Science.

[99]  M. McCarthy,et al.  Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes , 2007, Science.

[100]  A. Potter,et al.  Improvement of Human Islet Cryopreservation by a p38 MAPK Inhibitor , 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[101]  T. Hudson,et al.  A genome-wide association study identifies novel risk loci for type 2 diabetes , 2007, Nature.

[102]  M. Karin,et al.  NF-κB prevents β cell death and autoimmune diabetes in NOD mice , 2007, Proceedings of the National Academy of Sciences.

[103]  S. Futaki,et al.  Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor , 2007, Diabetologia.

[104]  D. Drucker The role of gut hormones in glucose homeostasis. , 2007, The Journal of clinical investigation.

[105]  J. Nielsen,et al.  Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity , 2006, Proceedings of the National Academy of Sciences.

[106]  Philippe Morel,et al.  International trial of the Edmonton protocol for islet transplantation. , 2006, The New England journal of medicine.

[107]  J. Neilson,et al.  Calcineurin/NFAT signalling regulates pancreatic β-cell growth and function , 2006, Nature.

[108]  N. Bodor,et al.  Corticosteroid design for the treatment of asthma: structural insights and the therapeutic potential of soft corticosteroids. , 2006, Current pharmaceutical design.

[109]  S. Robson,et al.  The transgenic expression of human CD39 on murine islets inhibits clotting of human blood. , 2006, Transplantation.

[110]  N. Fujii,et al.  Distinct Signals Regulate AS160 Phosphorylation in Response to Insulin, AICAR, and Contraction in Mouse Skeletal Muscle , 2006, Diabetes.

[111]  Yue Feng,et al.  Chronic Inhibition of Dipeptidyl Peptidase-4 With a Sitagliptin Analog Preserves Pancreatic β-Cell Mass and Function in a Rodent Model of Type 2 Diabetes , 2006, Diabetes.

[112]  A. Narang,et al.  Biological and Biomaterial Approaches for Improved Islet Transplantation , 2006, Pharmacological Reviews.

[113]  L. Cantley,et al.  Ras, PI(3)K and mTOR signalling controls tumour cell growth , 2006, Nature.

[114]  A. Sharma,et al.  Exendin-4 treatment improves metabolic control after rat islet transplantation to athymic mice with streptozotocin-induced diabetes , 2006, Diabetologia.

[115]  A. Siegbahn,et al.  Low Molecular Weight Dextran Sulfate: A Strong Candidate Drug to Block IBMIR in Clinical Islet Transplantation , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[116]  D. Drucker,et al.  Therapeutic approaches to preserve islet mass in type 2 diabetes. , 2006, Annual review of medicine.

[117]  Nils Welsh,et al.  Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. , 2005, Diabetes.

[118]  L. Groop,et al.  Genetic Prediction of Future Type 2 Diabetes , 2005, PLoS medicine.

[119]  U. Johansson,et al.  Composite Islet‐Endothelial Cell Grafts: A Novel Approach to Counteract Innate Immunity in Islet Transplantation , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[120]  R. Rizza,et al.  Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? , 2005, Diabetologia.

[121]  Jinquan Tan,et al.  Chemokine receptors and transplantation. , 2005, Cellular & molecular immunology.

[122]  B. Wehrle-Haller,et al.  Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function. , 2005, The Journal of clinical endocrinology and metabolism.

[123]  S. Bonner-Weir,et al.  Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment , 2005, Diabetologia.

[124]  J. Ruzzin,et al.  Glucocorticoid-induced insulin resistance in skeletal muscles: defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor , 2005, Diabetologia.

[125]  C. Ricordi,et al.  Islet Transplantation in Type 1 Diabetes Mellitus Using Cultured Islets and Steroid‐Free Immunosuppression: Miami Experience , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[126]  M. Cobb,et al.  ERK1/2-dependent Activation of Transcription Factors Required for Acute and Chronic Effects of Glucose on the Insulin Gene Promoter* , 2005, Journal of Biological Chemistry.

[127]  D. Roelen,et al.  Alloreactivity Against Repeated HLA Mismatches of Sequential Islet Grafts Transplanted in Non-Uremic Type 1 Diabetes Patients , 2005, Transplantation.

[128]  A. Shapiro,et al.  Five-year follow-up after clinical islet transplantation. , 2005, Diabetes.

[129]  P. Light,et al.  Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type and polymorphic beta-cell ATP-sensitive K+ channels. , 2005, Diabetes.

[130]  R. Schwenk,et al.  The E23K variant in the Kir6.2 subunit of the ATP-sensitive K+ channel does not augment impaired glucose tolerance in Caribbean subjects with a family history of type 2 diabetes. , 2005, The Journal of endocrinology.

[131]  N. Barshes,et al.  islet transplantation: implications for intrahepatic grafts , 2022 .

[132]  T. Matsuda,et al.  Inhibition of p38 Pathway Suppresses Human Islet Production of Pro‐Inflammatory Cytokines and Improves Islet Graft Function , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[133]  P. Carlsson,et al.  Better vascular engraftment and function in pancreatic islets transplanted without prior culture , 2005, Diabetologia.

[134]  M. Gassmann,et al.  Central Necrosis in Isolated Hypoxic Human Pancreatic Islets: Evidence for Postisolation Ischemia , 2005, Cell transplantation.

[135]  S. Bonner-Weir,et al.  Five stages of evolving beta-cell dysfunction during progression to diabetes. , 2004, Diabetes.

[136]  M. Laakso,et al.  Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. , 2004, The Journal of clinical endocrinology and metabolism.

[137]  J. Beckmann,et al.  Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. , 2004, Diabetes.

[138]  A. Caumo,et al.  First-phase insulin secretion: does it exist in real life? Considerations on shape and function. , 2004, American journal of physiology. Endocrinology and metabolism.

[139]  S. Ruchat,et al.  Dexamethasone-induced insulin resistance shows no gender difference in healthy humans. , 2004, Diabetes & metabolism.

[140]  J. Habener,et al.  Glucagon-like peptide 1 agonists and the development and growth of pancreatic β-cells , 2004 .

[141]  Noriko Okada,et al.  Inactivation of C5a Anaphylatoxin by a Peptide That Is Complementary to a Region of C5a 1 , 2004, The Journal of Immunology.

[142]  M. Daly,et al.  Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. , 2004, Diabetes.

[143]  F. Ashcroft,et al.  Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. , 2004, The New England journal of medicine.

[144]  R. Perfetti,et al.  GLP-1 inhibition of pancreatic islet cell apoptosis , 2004, Trends in Endocrinology & Metabolism.

[145]  A. Shapiro,et al.  Short-Term Storage of the Ischemically Damaged Human Pancreas by the Two-Layer Method Prior to Islet Isolation , 2004, Cell transplantation.

[146]  C. Berne,et al.  Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation1 , 2003, Transplantation.

[147]  Mogens Kruhøffer,et al.  Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. , 2003, Diabetes.

[148]  L. Chuang,et al.  National surveillance for type 2 diabetes mellitus in Taiwanese children. , 2003, JAMA.

[149]  M. Cobb,et al.  Regulation of ERK1 and ERK2 by Glucose and Peptide Hormones in Pancreatic β Cells* , 2003, Journal of Biological Chemistry.

[150]  D. Kaufman,et al.  Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipients. , 2003, Surgery.

[151]  M. Berridge,et al.  Calcium signalling: dynamics, homeostasis and remodelling , 2003, Nature reviews. Molecular cell biology.

[152]  C. Ferran,et al.  Genetic Engineering of a Suboptimal Islet Graft with A20 Preserves β Cell Mass and Function1 , 2003, The Journal of Immunology.

[153]  P. Heinke,et al.  IL-1β, IFN-γ and TNF-α increase vulnerability of pancreatic beta cells to autoimmune destruction , 2003 .

[154]  I. Chang,et al.  Nuclear Factor B Protects Pancreatic -Cells From Tumor Necrosis Factor-Mediated Apoptosis , 2003 .

[155]  G. Rutter,et al.  Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression. , 2003, The Biochemical journal.

[156]  P. Flecknell,et al.  Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression. , 2003, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[157]  R. Pederson,et al.  Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats , 2003 .

[158]  J. Egan,et al.  GLP‐1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells , 2003, Diabetes/metabolism research and reviews.

[159]  L. Chuang,et al.  Childhood diabetes identified in mass urine screening program in Taiwan, 1993-1999. , 2003, Diabetes research and clinical practice.

[160]  D. Drucker Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. , 2003, Molecular endocrinology.

[161]  M. McCarthy,et al.  Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. , 2003, Diabetes.

[162]  T. Hansen,et al.  The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes. , 2003, Diabetes.

[163]  S. Kahn,et al.  The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes , 2003, Diabetologia.

[164]  K. Ekdahl,et al.  Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation , 2002, The Lancet.

[165]  Khusru Asadullah,et al.  Mechanisms involved in the side effects of glucocorticoids. , 2002, Pharmacology & therapeutics.

[166]  S. Drago,et al.  Mechanisms involved in the beta-cell mass increase induced by chronic sucrose feeding to normal rats. , 2002, The Journal of endocrinology.

[167]  V. Giusti,et al.  Metabolic adaptations to dexamethasone-induced insulin resistance in healthy volunteers. , 2002, Obesity research.

[168]  P. Stork,et al.  Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. , 2002, Trends in cell biology.

[169]  K. Ekdahl,et al.  Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. , 2002, Diabetes.

[170]  R. Pederson,et al.  Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats. , 2002, Diabetes.

[171]  M. Schwanstecher,et al.  KIR6.2 Polymorphism Predisposes to Type 2 Diabetes by Inducing Overactivity of Pancreatic β-Cell ATP-Sensitive K+ Channels , 2002 .

[172]  J. Burén,et al.  Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in primary cultured rat adipocytes. , 2002, European journal of endocrinology.

[173]  J. Saklatvala Glucocorticoids: do we know how they work? , 2002, Arthritis Research & Therapy.

[174]  Stefan Fischer,et al.  Interleukin-8 release during early reperfusion predicts graft function in human lung transplantation. , 2002, American journal of respiratory and critical care medicine.

[175]  E. Furth,et al.  Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα , 2001, Nature Medicine.

[176]  F. Bach,et al.  Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. , 2001, Diabetes.

[177]  G. Korbutt,et al.  SERINE-PROTEASE INHIBITION DURING ISLET ISOLATION INCREASES ISLET YIELD FROM HUMAN PANCREASES WITH PROLONGED ISCHEMIA1 , 2001, Transplantation.

[178]  T. Tai,et al.  Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. , 2001, The Journal of clinical endocrinology and metabolism.

[179]  J. Morrissey,et al.  Tissue Factor: An Enzyme Cofactor and a True Receptor , 2001, Thrombosis and Haemostasis.

[180]  G. Steil,et al.  Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression. , 2001, American journal of physiology. Endocrinology and metabolism.

[181]  M. Kruhøffer,et al.  Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays. , 2001, Diabetes.

[182]  P. Liss,et al.  Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. , 2001, Diabetes.

[183]  F. Sundler,et al.  Beta Cell Adaptation to Dexamethasone-Induced Insulin Resistance in Rats Involves Increased Glucose Responsiveness but not Glucose Effectiveness , 2001, Pancreas.

[184]  S. Wiltshire,et al.  Association studies of variants in promoter and coding regions of beta‐cell ATP‐sensitive K‐channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53) , 2001, Diabetic medicine : a journal of the British Diabetic Association.

[185]  J. Lakey,et al.  Modulation of JNK and p38 Stress Activated Protein Kinases In Isolated Islets of Langerhans: Insulin as an Autocrine Survival Signal , 2001, Annals of surgery.

[186]  R. Bergman,et al.  Longitudinal Compensation for Fat-induced Insulin Resistance Includes Reduced Insulin Clearance and Enhanced ␤-cell Response Research Design and Methods , 2022 .

[187]  Eric S. Lander,et al.  The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes , 2000, Nature Genetics.

[188]  A. Khaghani,et al.  Tumor necrosis factor-alpha is expressed in donor heart and predicts right ventricular failure after human heart transplantation. , 2000, Circulation.

[189]  C. Wollheim,et al.  Synergistic activation of NF‐κb and inducible isoform of nitric oxide synthase induction by interferon‐γ and tumor necrosis factor‐α in INS‐1 cells , 2000, Journal of cellular physiology.

[190]  M. Stumvoll,et al.  Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. , 2000, Diabetes care.

[191]  G. Elgue,et al.  Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? , 1999, Diabetes.

[192]  A. Lorenzini,et al.  Insufficient adaptive capability of pancreatic endocrine function in dexamethasone-treated ageing rats. , 1999, The Journal of endocrinology.

[193]  J. Lakey,et al.  Activation and expression of ERK, JNK, and p38 MAP‐kinases in isolated islets of Langerhans: implications for cultured islet survival , 1999, FEBS letters.

[194]  B. Ahrén,et al.  Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity , 1999, Diabetologia.

[195]  P. de Vos,et al.  Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth? , 1999, Diabetes.

[196]  Å. Lernmark,et al.  Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients. , 1999, Diabetes.

[197]  C. Kahn,et al.  Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes , 1999, Cell.

[198]  J. Levy,et al.  Correct Homeostasis Model Assessment (HOMA) Evaluation Uses the Computer Program , 1998, Diabetes Care.

[199]  T. Ogihara,et al.  Pancreatic β Cell–specific Expression of  Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes , 1998, The Journal of experimental medicine.

[200]  B. Festoff,et al.  Thrombin Perturbs Neurite Outgrowth and Induces Apoptotic Cell Death in Enriched Chick Spinal Motoneuron Cultures through Caspase Activation , 1998, The Journal of Neuroscience.

[201]  E. Ferrannini Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: problems and prospects. , 1998, Endocrine reviews.

[202]  J. Gerich,et al.  The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity. , 1998, Endocrine reviews.

[203]  P. Liss,et al.  Measurements of oxygen tension in native and transplanted rat pancreatic islets. , 1998, Diabetes.

[204]  C. Östenson,et al.  Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release , 1998, Diabetologia.

[205]  C. Newgard,et al.  Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production. , 1998, The Journal of clinical investigation.

[206]  O. Domínguez,et al.  Endotoxin contamination may be responsible for the unexplained failure of human pancreatic islet transplantation. , 1998, Transplantation.

[207]  C. Ricordi,et al.  Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation. , 1998, Diabetes.

[208]  H. Dean NIDDM-Y in First Nation Children in Canada , 1998, Clinical pediatrics.

[209]  M. Permutt,et al.  A Nonsense Mutation in the Inward Rectifier Potassium Channel Gene, Kir6.2, Is Associated With Familial Hyperinsulinism , 1997, Diabetes.

[210]  S. Tonegawa,et al.  Reduced stress defense in heme oxygenase 1-deficient cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[211]  S. Tonegawa,et al.  Heme oxygenase 1 is required for mammalian iron reutilization. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[212]  C. Cotman,et al.  Thrombin Induces Apoptosis in Cultured Neurons and Astrocytes via a Pathway Requiring Tyrosine Kinase and RhoA Activities , 1997, The Journal of Neuroscience.

[213]  J. Juang,et al.  Fate of a small number of islets transplanted into diabetic mice. , 1997, Transplantation proceedings.

[214]  E. Lightner,et al.  Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy. , 1996, Human molecular genetics.

[215]  J. Sturis,et al.  Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance. , 1996, The New England journal of medicine.

[216]  G. Arteel,et al.  Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. , 1995, British Journal of Cancer.

[217]  R. Pederson,et al.  Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. , 1995, Endocrinology.

[218]  M. Mcdaniel,et al.  Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase , 1995, The Journal of experimental medicine.

[219]  S. Bonner-Weir,et al.  Beneficial Influence of Glycemic Control Upon the Growth and Function of Transplanted Islets , 1994, Diabetes.

[220]  N. Tajima,et al.  Epidemiology of type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in Japanese children. , 1994, Diabetes research and clinical practice.

[221]  J. Platt,et al.  The role of nitric oxide in IL-1 beta-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts. , 1994, Transplantation.

[222]  F. Assimacopoulos-Jeannet,et al.  Involvement of non-esterified fatty acid oxidation in glucocorticoid-induced peripheral insulin resistance in vivo in rats , 1993, Diabetologia.

[223]  B. Göke,et al.  Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. , 1993, The Journal of biological chemistry.

[224]  M. Mcdaniel,et al.  Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[225]  E. Leiter,et al.  Adoptive Transfer of Diabetes Into Immunodeficient NOD-scid/scid Mice: Relative Contributions of CD4+ and CD8+ T-Cells From Diabetic Versus Prediabetic NOD.NON-Thy-1a Donors , 1993, Diabetes.

[226]  C. Östenson,et al.  Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice. , 1992, The American journal of physiology.

[227]  M. Vranic,et al.  The diabetogenic effects of glucocorticoids are more pronounced in low- than in high-insulin responders. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[228]  R. DeFronzo,et al.  Pathogenesis of NIDDM: A Balanced Overview , 1992, Diabetes Care.

[229]  P. Tarr,et al.  Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[230]  S. Caughman,et al.  Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. , 1991, The Journal of biological chemistry.

[231]  G. Soldevila Cytotoxic effect of IFN-? plus TNF-a on human islet cells , 1991 .

[232]  R Berger,et al.  All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. , 1990, Blood.

[233]  Y. Mullen,et al.  Destruction of islet isografts by severe nonspecific inflammation. , 1990, Transplantation proceedings.

[234]  P. Morris,et al.  Exocrine contamination impairs implantation of pancreatic islets transplanted beneath the kidney capsule. , 1988, The Journal of surgical research.

[235]  J. Nerup,et al.  The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration. , 1988, Acta endocrinologica.

[236]  P. Southorn,et al.  Free radicals in medicine. I. Chemical nature and biologic reactions. , 1988, Mayo Clinic proceedings.

[237]  R. Rizza,et al.  Effects of glucocorticoids on carbohydrate metabolism. , 1988, Diabetes/metabolism reviews.

[238]  M. Davidson,et al.  Possible role for the glucose-fatty acid cycle in dexamethasone-induced insulin antagonism in rats. , 1987, Metabolism: clinical and experimental.

[239]  M. Feldmann,et al.  HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin , 1987, Nature.

[240]  C. Nathan,et al.  Secretory products of macrophages. , 1987, The Journal of clinical investigation.

[241]  K. Polonsky,et al.  Natural history of intrahepatic canine islet cell autografts. , 1986, The Journal of clinical investigation.

[242]  S. Bajaj,et al.  Activation of human factor VII in the initiation of tissue factor-dependent coagulation. , 1986, Blood.

[243]  J. Nerup,et al.  Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. , 1986, Science.

[244]  G. Eisenbarth Type I diabetes mellitus. A chronic autoimmune disease. , 1986 .

[245]  R. Turner,et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.

[246]  J. Halter,et al.  Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men. , 1984, The American journal of physiology.

[247]  H. P. Fletcher,et al.  Insulin release after acute hydrocortisone treatment in mice. , 1983, Metabolism: clinical and experimental.

[248]  D. Pipeleers,et al.  Determinants of the selective toxicity of alloxan to the pancreatic B cell. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[249]  Y. Z. Ider,et al.  Quantitative estimation of insulin sensitivity. , 1979, The American journal of physiology.

[250]  A. Matas,et al.  Pancreatic islet cell transplantation. , 1978, The Surgical clinics of North America.

[251]  P. Lacy,et al.  Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats , 1973, Diabetologia.

[252]  F. Leyh [On the therapy of acne vulgaris]. , 1972, Minerva medica.

[253]  M. Borowiec,et al.  Frequency of the E23K polymorphism of the KCNJ11 gene in children born small for gestational age and its influence on auxological and metabolic parameters in the prepubertal period , 2013, Journal of pediatric endocrinology & metabolism : JPEM.

[254]  W. Marsden I and J , 2012 .

[255]  A. Boschero,et al.  Insulin signaling proteins in pancreatic islets of insulin-resistant rats induced by glucocorticoid. , 2011, Biological research.

[256]  M. Son,et al.  A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis. , 2011, Diabetes research and clinical practice.

[257]  N. Rahman,et al.  A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2010 .

[258]  S. Taboga,et al.  Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets. , 2010, Endocrinology.

[259]  S. Siitonen,et al.  Hepatic IL‐8 release during graft procurement is associated with impaired graft function after human liver transplantation , 2010, Clinical transplantation.

[260]  A. Gruzman,et al.  Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a New Target for Antidiabetic Drugs: A Review on Metabolic, Pharmacological and Chemical Considerations. , 2009, The review of diabetic studies : RDS.

[261]  M. Karin,et al.  NF- κ B and Cancer — Identifying Targets and Mechanisms , 2008 .

[262]  J. Argente,et al.  Current Insights into the Genetic Basis of Diabetes Mellitus in Children and Adolescents , 2008, Journal of pediatric endocrinology & metabolism : JPEM.

[263]  S. Pervaiz,et al.  Apoptosis in the pathophysiology of diabetes mellitus. , 2007, The international journal of biochemistry & cell biology.

[264]  Neil Genzlinger A. and Q , 2006 .

[265]  Mark S. Anderson,et al.  The NOD mouse: a model of immune dysregulation. , 2005, Annual review of immunology.

[266]  S. Bonner-Weir,et al.  Five Stages of Evolving-Cell Dysfunction During Progression to Diabetes , 2004 .

[267]  R. van Schilfgaarde,et al.  Response of Encapsulated Rat Pancreatic Islets to Hypoxia , 2003, Cell Transplantation.

[268]  J. Juang,et al.  Beneficial effects of hyperbaric oxygen therapy on islet transplantation. , 2002, Cell transplantation.

[269]  M. Permutt,et al.  An E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARγ Pro12Ala variant , 2002, Diabetologia.

[270]  F. Bach,et al.  Carbon Monoxide Protects Pancreatic -Cells From Apoptosis and Improves Islet Function/Survival After , 2002 .

[271]  P. Corris,et al.  Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantation. , 2001, American journal of respiratory and critical care medicine.

[272]  Ames,et al.  Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen , 2000 .

[273]  L. Aguilar-Bryan,et al.  Familial hyperinsulinism and pancreatic -cell ATP-sensitive potassium channels , 2000 .

[274]  T. Miki,et al.  The structure and function of the ATP-sensitive K channel in insulin-secreting pancreatic â-cells , 1999 .

[275]  K. Kunjilwar,et al.  Toward understanding the assembly and structure of KATP channels. , 1998, Physiological reviews.

[276]  S. Lenzen,et al.  Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. , 1996, Free radical biology & medicine.

[277]  A. McConnell Free radicals in medicine , 1995 .

[278]  B. Zikria,et al.  Reperfusion injuries and clinical capillary leak syndrome , 1994 .

[279]  M. Grilli,et al.  NF-kappa B and Rel: participants in a multiform transcriptional regulatory system. , 1993, International review of cytology.

[280]  P. Lankisch [Chronic pancreatitis]. , 1991, Der Internist.

[281]  J. Downey,et al.  Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion? , 1986, Acta physiologica Scandinavica. Supplementum.

[282]  H. Imura,et al.  The Insulinogenic Index in Secondary Diabetes , 1975 .