A new approach of delivering siRNA to the cornea and its application for inhibiting herpes simplex keratitis.
暂无分享,去创建一个
[1] Y. Oike,et al. Angiopoietin-like protein 2 is a potent hemangiogenic and lymphangiogenic factor in corneal inflammation. , 2013, Investigative ophthalmology & visual science.
[2] L. Hazlett,et al. TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway. , 2013, Investigative ophthalmology & visual science.
[3] W. Hauswirth,et al. A comprehensive review of retinal gene therapy. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[4] Minbin Yu,et al. Inhibition of Pirfenidone on TGF-beta2 Induced Proliferation, Migration and Epithlial-Mesenchymal Transition of Human Lens Epithelial Cells Line SRA01/04 , 2013, PloS one.
[5] Kang Chen,et al. MRP8/14 enhances corneal susceptibility to Pseudomonas aeruginosa Infection by amplifying inflammatory responses. , 2013, Investigative ophthalmology & visual science.
[6] K. Newkirk,et al. Evaluation of delivery agents used for introduction of small interfering RNAs into feline corneal cells. , 2013, American journal of veterinary research.
[7] L. N. Borgheti-Cardoso,et al. Delivery Systems and Local Administration Routes for Therapeutic siRNA , 2013, Pharmaceutical Research.
[8] L. Xiong,et al. SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[9] R. Mayer,et al. Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis , 2013, Molecular therapy. Nucleic acids.
[10] D. Fischer,et al. Recent developments and perspectives on gene therapy using synthetic vectors. , 2013, Therapeutic delivery.
[11] K. Haghani,et al. siRNA therapeutics in the treatment of diseases. , 2013, Therapeutic delivery.
[12] Asim V. Farooq,et al. Herpes simplex epithelial and stromal keratitis: an epidemiologic update. , 2012, Survey of ophthalmology.
[13] U. Krishnan,et al. Translational siRNA therapeutics using liposomal carriers: prospects & challenges. , 2012, Current gene therapy.
[14] Juliane Nguyen,et al. Nucleic acid delivery: the missing pieces of the puzzle? , 2012, Accounts of chemical research.
[15] Brian C. Stagg,et al. Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization. , 2012, Investigative ophthalmology & visual science.
[16] Xinyi Wu,et al. Toll‐like receptor 2 siRNA suppresses corneal inflammation and attenuates Aspergillus fumigatus keratitis in rats , 2012, Immunology and cell biology.
[17] J. Tovey,et al. Gene therapy in the Cornea: 2005–present , 2012, Progress in Retinal and Eye Research.
[18] Kaili Wu,et al. Small interfering RNA targeting for infected‐cell polypeptide 4 inhibits herpes simplex virus type 1 replication in retinal pigment epithelial cells , 2011, Clinical & experimental ophthalmology.
[19] T. Ritter,et al. Role of Lentivirus‐Mediated Overexpression of Programmed Death‐Ligand 1 on Corneal Allograft Survival , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[20] J. Burnett,et al. Current progress of siRNA/shRNA therapeutics in clinical trials , 2011, Biotechnology journal.
[21] Chia-Yang Liu,et al. Polymeric micelle gene delivery of bcl-xL via eye drop reduced corneal apoptosis following epithelial debridement. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[22] Feng Wang,et al. A SiRNA Targeting Vascular Endothelial Growth Factor-A Inhibiting Experimental Corneal Neovascularization , 2010, Current eye research.
[23] Chia-Yang Liu,et al. Gene delivery to cornea , 2010, Brain Research Bulletin.
[24] Xinyi Wu,et al. JNK1/2 siRNA inhibits transforming-growth factor-β1-induced connective tissue growth factor expression and fibrotic function in THSFs , 2010, Molecular and Cellular Biochemistry.
[25] Chia-Yang Liu,et al. Electrically assisted delivery of macromolecules into the corneal epithelium. , 2009, Experimental eye research.
[26] X. Xia,et al. [Inhibitory effect of interfering RNA targeting HIF-1alpha and VEGF on retinal neovascularization in the mouse]. , 2008, [Zhonghua yan ke za zhi] Chinese journal of ophthalmology.
[27] T. Foster,et al. Ocular HSV-1 Latency, Reactivation and Recurrent Disease , 2008, Seminars in ophthalmology.
[28] P. Davis,et al. Vectors for airway gene delivery , 2007, The AAPS Journal.
[29] D. Peer,et al. Corneal gene therapy. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[30] Chia-Yang Liu,et al. Eye drop delivery of nano‐polymeric micelle formulated genes with cornea‐specific promoters , 2007, The journal of gene medicine.
[31] P. Jani,et al. Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis. , 2007, Investigative ophthalmology & visual science.
[32] K. Yau,et al. In vivo gene delivery in the retina using polyethylenimine. , 2007, BioTechniques.
[33] B. Pitard,et al. Relationships between the physicochemical properties of an amphiphilic triblock copolymers/DNA complexes and their intramuscular transfection efficiency , 2006, Nucleic acids research.
[34] G. Rao,et al. Role of amniotic membrane graft for ocular chemical and thermal injuries. , 2007, Cornea.
[35] H. Lipps,et al. Designing nonviral vectors for efficient gene transfer and long-term gene expression. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[36] J. Lieberman,et al. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection , 2006, Nature.
[37] D. Fischer,et al. Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives , 2005, The journal of gene medicine.
[38] T. Irimura,et al. Antitumor Activity of Small Interfering RNA/Cationic Liposome Complex in Mouse Models of Cancer , 2004, Clinical Cancer Research.
[39] T. Tumpey,et al. Protection against lethal influenza virus challenge by RNA interference in vivo. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[40] G. Ying,et al. INTRAVITREAL INJECTION OF VASCULAR ENDOTHELIAL GROWTH FACTOR SMALL INTERFERING RNA INHIBITS GROWTH AND LEAKAGE IN A NONHUMAN PRIMATE, LASER-INDUCED MODEL OF CHOROIDAL NEOVASCULARIZATION , 2004, Retina.
[41] I. Kwon,et al. A Cationic Lipid Emulsion/DNA Complex as a Physically Stable and Serum-Resistant Gene Delivery System , 2000, Pharmaceutical Research.
[42] M. Balda,et al. Functional analysis of tight junctions. , 2003, Methods.
[43] W. Kao,et al. Corneal Epithelial Wound Healing , 2001, Experimental biology and medicine.
[44] J. Liaw,et al. In vivo gene delivery into ocular tissues by eye drops of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) polymeric micelles , 2001, Gene Therapy.
[45] J. Weir. Regulation of herpes simplex virus gene expression. , 2001, Gene.
[46] T. Tuschl,et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.
[47] A. Mikos,et al. Poly(ethylenimine)-mediated gene delivery affects endothelial cell function and viability. , 2001, Biomaterials.
[48] K. Tsubota,et al. Adenovirus-mediated gene transfer to the ocular surface epithelium. , 1998, Experimental eye research.
[49] C. Benoist,et al. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. , 1996, Human gene therapy.
[50] D. Scherman,et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[51] D. Easty,et al. Passive immunization protects the mouse eye from damage after herpes simplex virus infection by limiting spread of virus in the nervous system. , 1990, The Journal of general virology.
[52] J. Madara,et al. Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity , 1986, The Journal of cell biology.
[53] J. Metcalf,et al. Herpetic keratitis in inbred mice. , 1984, Investigative ophthalmology & visual science.
[54] D. Easty,et al. Ocular infection with herpes simplex virus in nonimmune and immune mice. , 1983, Archives of ophthalmology.