A clustering-based method for single-channel fetal heart rate monitoring

Non-invasive fetal electrocardiography (ECG) is based on the acquisition of signals from abdominal surface electrodes. The composite abdominal signal consists of the maternal electrocardiogram along with the fetal electrocardiogram and other electrical interferences. These recordings allow for the acquisition of valuable and reliable information that helps ensure fetal well-being during pregnancy. This paper introduces a procedure for fetal heart rate extraction from a single-channel abdominal ECG signal. The procedure is composed of three main stages: a method based on wavelet for signal denoising, a new clustering-based methodology for detecting fetal QRS complexes, and a final stage to correct false positives and false negatives. The novelty of the procedure thus relies on using clustering techniques to classify singularities from the abdominal ECG into three types: maternal QRS complexes, fetal QRS complexes, and noise. The amplitude and time distance of all the local maxima followed by a local minimum were selected as features for the clustering classification. A wide set of real abdominal ECG recordings from two different databases, providing a large range of different characteristics, was used to illustrate the efficiency of the proposed method. The accuracy achieved shows that the proposed technique exhibits a competitve performance when compared to other recent works in the literature and a better performance over threshold-based techniques.

[1]  Fionn Murtagh,et al.  Algorithms for hierarchical clustering: an overview , 2012, WIREs Data Mining Knowl. Discov..

[2]  Paul S Addison,et al.  Wavelet transforms and the ECG: a review , 2005, Physiological measurement.

[3]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[4]  Johann Bauersachs,et al.  [Cardiovascular disease in pregnancy]. , 2016, Deutsche medizinische Wochenschrift.

[5]  Hagen Malberg,et al.  Robust fetal ECG extraction and detection from abdominal leads , 2014, Physiological measurement.

[6]  Janusz Jezewski,et al.  Determination of fetal heart rate from abdominal signals: evaluation of beat-to-beat accuracy in relation to the direct fetal electrocardiogram , 2012, Biomedizinische Technik. Biomedical engineering.

[7]  Joydeep Ghosh,et al.  Data Clustering Algorithms And Applications , 2013 .

[8]  Alberto J. Palma,et al.  One-step wavelet-based processing for wandering and noise removing in ECG signals , 2013, IWBBIO.

[9]  Li Su,et al.  Extract Fetal ECG from Single-Lead Abdominal ECG by De-Shape Short Time Fourier Transform and Nonlocal Median , 2016, Front. Appl. Math. Stat..

[10]  R. Vullings,et al.  A systematic review of prenatal screening for congenital heart disease by fetal electrocardiography , 2016, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[11]  Hernâni Gonçalves,et al.  Fetal QRS detection and heart rate estimation: a wavelet-based approach. , 2014, Physiological measurement.

[12]  J. Roos‐Hesselink,et al.  Pregnancy and delivery in cardiac disease. , 2013, Journal of cardiology.

[13]  Rami J. Oweis,et al.  Review Article: Non-Invasive Fetal Heart Rate Monitoring Techniques , 2014 .

[14]  D. Panigrahy,et al.  Extraction of fetal ECG signal by an improved method using extended Kalman smoother framework from single channel abdominal ECG signal , 2017, Australasian Physical & Engineering Sciences in Medicine.

[15]  Brian Everitt,et al.  Cluster analysis , 1974 .

[16]  Tao Zhang,et al.  Coarse Alignment Technology on Moving Base for SINS Based on the Improved Quaternion Filter Algorithm , 2017, Sensors.

[17]  J. Morlet,et al.  [16] Mallat, S. (1989) \A Theory for Multiresolution Signal Decomposition: The Wavelet Representation, " IEEE Transactions on Pattern Analysis and Machine Intelligence, , 1995 .

[18]  G. De Soete,et al.  Clustering and Classification , 2019, Data-Driven Science and Engineering.

[19]  Joachim Behar,et al.  A Comparison of Single Channel Fetal ECG Extraction Methods , 2014, Annals of Biomedical Engineering.

[20]  Reza Sameni,et al.  Noninvasive fetal ECG: The PhysioNet/Computing in Cardiology Challenge 2013 , 2013, Computing in Cardiology 2013.

[21]  Dimitrios I. Fotiadis,et al.  Detection of Fetal Heart Rate Through 3-D Phase Space Analysis From Multivariate Abdominal Recordings , 2009, IEEE Transactions on Biomedical Engineering.

[22]  Stéphane Mallat,et al.  A Theory for Multiresolution Signal Decomposition: The Wavelet Representation , 1989, IEEE Trans. Pattern Anal. Mach. Intell..

[23]  H. Yazdani,et al.  New similarity functions , 2016, 2016 Third International Conference on Artificial Intelligence and Pattern Recognition (AIPR).

[24]  Ganapati Panda,et al.  A survey on nature inspired metaheuristic algorithms for partitional clustering , 2014, Swarm Evol. Comput..

[25]  Alberto J. Palma,et al.  Efficient wavelet-based ECG processing for single-lead FHR extraction , 2013, Digit. Signal Process..

[26]  Dilbag Singh,et al.  Quantification of Feto-Maternal Heart Rate from Abdominal ECG Signal Using Empirical Mode Decomposition for Heart Rate Variability Analysis , 2017 .

[27]  Anita Krishnan,et al.  Feasibility of Noninvasive Fetal Electrocardiographic Monitoring in a Clinical Setting , 2015, Pediatric Cardiology.

[28]  Alireza Mehrnia,et al.  A novel low-complexity digital filter design for wearable ECG devices , 2017, PloS one.

[29]  Pedro Álvarez,et al.  Classification Algorithms for Fetal QRS Extraction in Abdominal ECG Signals , 2017, IWBBIO.

[30]  Yoshitaka Kimura,et al.  Recent Advances in Fetal Electrocardiography , 2012 .

[31]  Boreom Lee,et al.  Sequential Total Variation Denoising for the Extraction of Fetal ECG from Single-Channel Maternal Abdominal ECG , 2016, Sensors.

[32]  Manabu Ichino,et al.  Generalized Minkowski metrics for mixed feature-type data analysis , 1994, IEEE Trans. Syst. Man Cybern..

[33]  D P Morales,et al.  An application of reconfigurable technologies for non-invasive fetal heart rate extraction. , 2013, Medical engineering & physics.

[34]  Junjie Wu,et al.  Advances in K-means clustering: a data mining thinking , 2012 .

[35]  Antonio Gasbarrini,et al.  Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluations from the PITER network , 2017, PloS one.

[36]  G. Saha,et al.  Fetal ECG extraction from single-channel maternal ECG using singular value decomposition , 1997, IEEE Transactions on Biomedical Engineering.

[37]  Lei Wang,et al.  A Novel Technique for Fetal ECG Extraction Using Single-Channel Abdominal Recording , 2017, Sensors.

[38]  Alberto J. Palma,et al.  Noise Suppression in ECG Signals through Efficient One-Step Wavelet Processing Techniques , 2013, J. Appl. Math..