Diagnosing residual aphasia using spontaneous speech analysis

Background: It is well known that about 20% of patients with anomic aphasia still show residual aphasic symptoms 1 year post onset. As we do not have any tests to reliably diagnose residual aphasia it is difficult to decide whether these persisting problems are signs of residual aphasia that have to be treated, or are indications of a normal variability in language use, which also may occur in elderly people. Aims: The main aim of this research is to find out whether there are variables in spontaneous communication of persons with residual aphasia (P-RA) that enable us to distinguish them from persons without aphasia (P-NA). Methods & Procedures: Following a detailed linguistic analysis of spontaneous speech we employed binary logistic regression analysis to find the most relevant variables for differentiation between P-RA (N = 41) and P-NA (N = 25). Outcomes & Results: Significant group differences at different processing levels could be observed. Lexically varied, informative, and cohesively tied phrases in particular pose the main problem for P-RA. Regression analysis including variables of spontaneous communication explains 82.5% (R2) of the variation and correctly identifies 39 of 41 (95.1%) cases of P-RA and 21 of 25 (84.0%) cases of P-NA. Conclusions: Analysing spontaneous communication seems to be a promising possibility for diagnosing residual aphasia. The importance of spontaneous communication in everyday interaction, and its sensitivity to even slight deficits in language processing, promote the described analysis as a very useful screening instrument to distinguish P-RA from P-NA.

[1]  M. Cole Language Intervention Strategies in Adult Aphasia, 3rd Ed. , 1994, Neurology.

[2]  J. S. McClung,et al.  Human Neuroscience , 2022 .

[3]  Sandhi Maria Barreto,et al.  Oral language comprehension assessment among elderly: a population based study in Brazil. , 2009, Preventive medicine.

[4]  Neuropsychologie im Alltag , 2002 .

[5]  B. Murdoch,et al.  Narrative discourse in multiple sclerosis : An investigation of conceptual structure , 1997 .

[6]  J W Krakauer,et al.  Variability in language recovery after first-time stroke , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.

[7]  Guila Glosser,et al.  Patterns of discourse production among neurological patients with fluent language disorders , 1991, Brain and Language.

[8]  Yves Joanette,et al.  Unconstrained oral naming performance in right- and left-hemisphere-damaged individuals: When education overrides the lesion , 2003 .

[9]  J. Rickford,et al.  Syntactic Variation and Change in Progress: Loss of the Verbal Coda in Topic-Restricting as Far as Constructions. , 1995 .

[10]  Serguei V. S. Pakhomov,et al.  Computerized Analysis of Speech and Language to Identify Psycholinguistic Correlates of Frontotemporal Lobar Degeneration , 2010, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.

[11]  Marilyn Newhoff,et al.  Measures of lexical diversity in aphasia , 2003 .

[12]  L. Murray The Effects of Varying Attentional Demands on the Word Retrieval Skills of Adults with Aphasia, Right Hemisphere Brain Damage, or No Brain Damage , 2000, Brain and Language.

[13]  Hanna K. Ulatowska,et al.  Making stories: Evaluative language and the aphasia experience , 2007 .

[14]  Luc P de Witte,et al.  Psychometric properties of the community integration questionnaire adjusted for people with aphasia. , 2010, Archives of physical medicine and rehabilitation.

[15]  R. Wilkinson Sequentiality as a problem and resource for intersubjectivity in aphasic conversation: analysis and implications for therapy , 1999 .

[16]  T. Olsen,et al.  Aphasia in acute stroke: Incidence, determinants, and recovery , 1995, Annals of neurology.

[17]  K Willmes,et al.  The Aachen Aphasia Test. , 1984, Advances in neurology.

[18]  S. Matteson,et al.  “Let me tell you the point”: How speakers with aphasia assign prominence to information in narratives , 2010 .

[19]  D. Holmes,et al.  A stylometric analysis of conversational speech of aphasic patients , 1996 .

[20]  C M Shewan,et al.  Reliability and validity characteristics of the Western Aphasia Battery (WAB). , 1980, The Journal of speech and hearing disorders.

[21]  Elizabeth Bates,et al.  Differential Effects of Unilateral Lesions on Language Production in Children and Adults , 2001, Brain and Language.

[22]  P. Doyle,et al.  The Communicative Informativeness and Efficiency of Connected Discourse by Adults With Aphasia Under Structured and Conversational Sampling Conditions , 1995 .

[23]  L. Armstrong,et al.  Cohesion analysis of the expository discourse of normal, fluent aphasic and demented adults: A role in differential diagnosis? , 1997 .

[24]  A. Ferguson,et al.  Language, meaning, context, and functional communication , 2010 .

[25]  R. Duffy,et al.  Longitudinal Assessment of Narrative Discourse in a Mildly Aphasic Adult , 1994 .

[26]  E. Renzi,et al.  The token test: A sensitive test to detect receptive disturbances in aphasics. , 1962, Brain : a journal of neurology.

[27]  G. Glosser,et al.  A comparison of changes in macrolinguistic and microlinguistic aspects of discourse production in normal aging. , 1992, Journal of gerontology.

[28]  Luise Springer,et al.  Klinik und Rehabilitation der Aphasie: Eine Einführung für Therapeuten, Angehörige und Betroffene , 2013 .

[29]  Larry Boles,et al.  Conversational treatment in mild aphasia: A case study , 2009 .

[30]  C. Boeckx Language in Cognition , 2009 .

[31]  Ying Li,et al.  Designing a Free Style, Indirect, and Interactive Storytelling Application for People with Aphasia , 2007, INTERACT.

[32]  S. Chapman,et al.  Discourse in fluent aphasia and Alzheimer's disease: Linguistic and pragmatic considerations , 1998, Journal of Neurolinguistics.

[33]  Susan Edwards,et al.  Fluent aphasia in three languages: Aspects of spontaneous speech , 1996 .

[34]  R. Wertz,et al.  Accuracy of formal tests for diagnosing mild aphasia: An application of evidence‐based medicine , 2004 .

[35]  W. Huber,et al.  Zum Verhältnis von Kohärenz und Kohäsion bei Aphasie , 1992 .

[36]  L. Murray,et al.  Grammaticality judgements of mildly aphasic individuals under dual-task conditions , 1997 .

[37]  E. C. Li,et al.  The influence of topic and listener familiarity on aphasic discourse. , 1994, Journal of communication disorders.

[38]  Evelyn C. Ferstl,et al.  Text comprehension after brain injury: left prefrontal lesions affect inference processes. , 2002, Neuropsychology.

[39]  A. J. North,et al.  Production of narrative and procedural discourse in aphasia , 1981, Brain and Language.

[40]  W. Huber,et al.  “Prepairs” and repairs: Different monitoring functions in aphasic language production , 1987, Brain and Language.

[41]  R. Hartsuiker,et al.  Syntactic priming persists while the lexical boost decays : Evidence from written and spoken dialogue , 2008 .

[42]  M. Just,et al.  Language comprehension: sentence and discourse processing. , 1995, Annual review of psychology.

[43]  W. Huber,et al.  Die Supplemente zum Aachener Aphasie Test: Aufbau und Resultate der Validierung , 1993 .

[44]  S. Chapman,et al.  Conversational discourse in aphasia , 1992 .

[45]  K. Poeck,et al.  [The Aachen Aphasia Test Rationale and construct validity (author's transl)]. , 1980, Der Nervenarzt.

[46]  R. Bender1,et al.  Multiples Testen , 2002 .

[47]  Laura L. Murray,et al.  Distinguishing clinical depression from early Alzheimer's disease in elderly people: Can narrative analysis help? , 2010 .

[48]  L. Lapointe Aphasia And Related Neurogenic Language Disorders , 1997 .

[49]  Alison Wray,et al.  The functions of formulaic language: an integrated model , 2000 .

[50]  L. Nickels,et al.  “I’m sitting here feeling aphasic!” A study of recurrent perseverative errors elicited in unimpaired speakers , 2004, Brain and Language.

[51]  Michael Halliday,et al.  Cohesion in English , 1976 .

[52]  S. Blumstein,et al.  Syntactic priming effects in aphasia: An investigation of local syntactic dependencies , 1991, Brain and Language.

[53]  R. Hartsuiker,et al.  Syntactic Facilitation in Agrammatic Sentence Production , 1998, Brain and Language.

[54]  L. Murray,et al.  Functional measures of naming in aphasia: Word retrieval in confrontation naming versus connected speech , 2003 .

[55]  R. Bastiaanse,et al.  Analysing the spontaneous speech of aphasic speakers , 2004 .

[56]  L. Milroy,et al.  Repair strategies in aphasic discourse; towards a collaborative model. , 1992, Clinical linguistics & phonetics.

[57]  I. T. Draper THE ASSESSMENT OF APHASIA AND RELATED DISORDERS , 1973 .

[58]  Bobbie Beckman,et al.  Comprehension and Storage of Four Serially Presented Radio News Stories by Mild Aphasic Subjects , 2000, Brain and Language.

[59]  M. Rousseaux,et al.  An analysis of communication in conversation after severe traumatic brain injury , 2010, European journal of neurology.

[60]  M. Pickering,et al.  Toward a mechanistic psychology of dialogue , 2004, Behavioral and Brain Sciences.

[61]  T. Watamori,et al.  Production of discourse in high-functioning individuals with aphasia----with reference to performance on the Japanese CADL , 1999 .

[62]  Evelyn C. Ferstl,et al.  Text Comprehension in Middle Aged Adults: Is There Anything Wrong? , 2006, Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.

[63]  R. Brookshire,et al.  A system for quantifying the informativeness and efficiency of the connected speech of adults with aphasia. , 1993, Journal of speech and hearing research.

[64]  Masayuki Komachi,et al.  Language in Cognition: Uncovering Mental Structures and the Rules Behind Them , 2012 .

[65]  J. Mazaux,et al.  Communication impairment and activity limitation in stroke patients with severe aphasia , 2011, Disability and rehabilitation.

[66]  R. Wertz,et al.  Possible demographic influences on differentiating normal from aphasic performance. , 2001, Journal of communication disorders.

[67]  R H Brookshire,et al.  Presence, completeness, and accuracy of main concepts in the connected speech of non-brain-damaged adults and adults with aphasia. , 1995, Journal of speech and hearing research.

[68]  Martina Piefke,et al.  Basic parameters of spontaneous speech as a sensitive method for measuring change during the course of aphasia. , 2008, International journal of language & communication disorders.

[69]  R. Brookshire,et al.  Performance Deviations in the Connected Speech of Adults With No Brain Damage and Adults With Aphasia , 1995 .

[70]  L. Murray,et al.  Spoken language of individuals with mild fluent aphasia under focused and divided-attention conditions. , 1998, Journal of speech, language, and hearing research : JSLHR.

[71]  Alexandra A. Cleland,et al.  Syntactic alignment and participant role in dialogue , 2007, Cognition.

[72]  Nadine Martin,et al.  Effects of Structural Priming on Sentence Production in Aphasics , 1997 .

[73]  Marianne Lind,et al.  Semi-spontaneous oral text production: Measurements in clinical practice , 2009, Clinical linguistics & phonetics.

[74]  M. Alexander,et al.  Verbal memory function in mild aphasia , 1996, Neurology.

[75]  K. Willmes,et al.  The psychometric properties of the English language version of the Aachen Aphasia Test (EAAT) , 2000 .

[76]  E. Kaplan,et al.  Variations in aphasic language behaviors. , 1988, The Journal of speech and hearing disorders.

[77]  Juliana Onofre DE Lira,et al.  Microlinguistic aspects of the oral narrative in patients with Alzheimer's disease , 2010, International Psychogeriatrics.

[78]  Jim Miller,et al.  Spontaneous Spoken Language: Syntax and Discourse , 1998 .

[79]  Connie A. Tompkins,et al.  Context and word class influences on lexical retrieval in aphasia , 2002 .

[80]  L. Perkins Applying conversation analysis to aphasia: clinical implications and analytic issues. , 1995, European journal of disorders of communication : the journal of the College of Speech and Language Therapists, London.