Elastic valve and microfluidic device with the same

An elastic valve is provided to close a channel to restore elastically even though the external force making a channel shriveled is not excessively great, and to improve the reliability of channel closure with the deformation of the channel protrusion regardless of the shape of channel section. An elastic valve(120) comprises an elastic valve, a channel(122) shriveled to be restored with external force, and a plurality of channel closing protrusions(130). If the external force is applied so that channel become shriveled, a plurality of channel closing protrusions close the channels by being deformed. A plurality of channel closing protrusions are protruded toward the inner side facing the inner side of at least one side of the channel, is separated from each other not to disturb the flow of the fluid and is made of elastomer materials.