Classification of the Colonic Polyps in CT-Colonography Using Region Covariance as Descriptor Features of Suspicious Regions

We present an algorithm to classify polyps in CT colonography images utilizing covariance matrices as object descriptors. Since these descriptors do not lie on a vector space, they cannot simply be fed to traditional machine learning tools such as support vector machines (SVMs) or artificial neural networks (ANNs). To benefit from the simple yet one of the most powerful nonparametric machine learning approach k-nearest neighbor classifier, it suffices to compute the pairwise distances among the covariance descriptors using a distance metric involving their generalized eigenvalues, which also follows from the Lie group structure of positive definite matrices. This approach is fast and discriminates polyps from non-polyps with high accuracy using only a small size descriptor, which consists of 36 unique features per image region extracted from the suspicious regions that we have obtained by combined cellular neural network (CNN) and template matching detection method. These suspicious regions are, in average, 15 × 17 = 255 pixels in our experiments.

[1]  Hiroyuki Yoshida,et al.  Three-dimensional computer-aided diagnosis scheme for detection of colonic polyps , 2001, IEEE Transactions on Medical Imaging.

[2]  Marek Franaszek,et al.  Support vector machines committee classification method for computer-aided polyp detection in CT colonography. , 2005, Academic radiology.

[3]  Ronald M. Summers,et al.  Wavelet method for CT colonography computer-aided polyp detection , 2006, 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006..

[4]  Subhas Banerjee,et al.  CT colonography for colon cancer screening. , 2006, Gastrointestinal endoscopy.

[5]  D. Nizri,et al.  New imaging techniques in oncology , 2003 .

[6]  Onur Osman,et al.  Colonic Polyp Detection in CT Colonography with Fuzzy Rule Based 3D Template Matching , 2009, Journal of Medical Systems.

[7]  Ronald M. Summers,et al.  Feature selection for computer-aided polyp detection using genetic algorithms , 2003, SPIE Medical Imaging.

[8]  Onur Osman,et al.  A preliminary study on computerized lesion localization in MR mammography using 3D nMITR maps, multilayer cellular neural networks, and fuzzy c-partitioning. , 2007, Medical physics.

[9]  Ronald M. Summers,et al.  Support vector machines committee classification method for computer-aided polyp detection in CT colonography1 , 2005 .

[10]  Ronald M. Summers,et al.  Colonic polyp segmentation in CT colonography-based on fuzzy clustering and deformable models , 2004, IEEE Transactions on Medical Imaging.

[11]  Fatih Murat Porikli,et al.  Region Covariance: A Fast Descriptor for Detection and Classification , 2006, ECCV.

[12]  Fatih Murat Porikli,et al.  Robust License Plate Detection Using Covariance Descriptor in a Neural Network Framework , 2006, 2006 IEEE International Conference on Video and Signal Based Surveillance.

[13]  W. Förstner,et al.  A Metric for Covariance Matrices , 2003 .

[14]  Onur Osman,et al.  AUTOMATIC COLON SEGMENTATION USING CELLULAR NEURAL NETWORK FOR THE DETECTION OF COLORECTAL POLYPS , 2007 .

[15]  Marek Franaszek,et al.  Multiple neural network classification scheme for detection of colonic polyps in CT colonography data sets. , 2003, Academic radiology.

[16]  J G Fletcher,et al.  CT colonography (virtual colonoscopy) for the detection of colorectal polyps and neoplasms. current status and future developments. , 2002, European journal of cancer.

[17]  M. Macari,et al.  Virtual colonoscopy: clinical results. , 2001, Seminars in ultrasound, CT, and MR.

[18]  A. M. Youssef,et al.  Automated polyp detection at CT colonography: feasibility assessment in a human population. , 2001, Radiology.

[19]  Ronald M. Summers,et al.  Multi network classification scheme for detection of colonic polyps in CT colonography data sets , 2002, Proceedings IEEE International Symposium on Biomedical Imaging.

[20]  Paul F. Whelan,et al.  The use of 3D surface fitting for robust polyp detection and classification in CT colonography , 2006, Comput. Medical Imaging Graph..