Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia
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[1] B. Mittal,et al. Association of Functionally Important Polymorphism of Microsomal Epoxide Hydrolase Gene (EPHX1) With Lung Cancer Susceptibility , 2011, Cancer investigation.
[2] R. Vierkant,et al. Xenobiotic‐Metabolizing gene polymorphisms and ovarian cancer risk , 2011, Molecular carcinogenesis.
[3] M. Ingelman-Sundberg,et al. Genetic polymorphism and toxicology--with emphasis on cytochrome p450. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.
[4] C. Tanrikut,et al. DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood acute lymphoblastic leukemia. , 2010, Leukemia research.
[5] T. Isbir,et al. Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis. , 2010, Tumori.
[6] E. Arinç,et al. The role of polymorphic cytochrome P450 enzymes in drug design, development and drug interactions with a special emphasis on phenotyping , 2010 .
[7] C. Scrideli,et al. Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children , 2009, Environmental and molecular mutagenesis.
[8] M. Arand,et al. Mammalian epoxide hydrolases in xenobiotic metabolism and signalling , 2009, Archives of Toxicology.
[9] B. Mittal,et al. Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer. , 2008, Toxicology and applied pharmacology.
[10] S. Ahmed,et al. Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) Polymorphisms in Breast Carcinoma , 2008, BMC Cancer.
[11] D. Srivastava,et al. Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India , 2008, Archives of Toxicology.
[12] R. D. Mittal,et al. Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer. , 2007, DNA and cell biology.
[13] C. V. van Duijn,et al. Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population , 2007, BMC Cancer.
[14] O. Adalı,et al. Significance of Genetic Polymorphisms at Multiple Loci of CYP2E1 in the Risk of Development of Childhood Acute Lymphoblastic Leukemia , 2007, Oncology.
[15] O. Adalı,et al. The low frequency of defective TPMT alleles in Turkish population: A study on pediatric patients with acute lymphoblastic leukemia , 2007, American journal of hematology.
[16] I. Ember,et al. Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. , 2007, Anticancer research.
[17] O. Adalı,et al. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population , 2007, Archives of Toxicology.
[18] S. Z. Abdel‐Rahman,et al. Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene. , 2007, Chemico-biological interactions.
[19] D. Colomer,et al. The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia. , 2007, Haematologica.
[20] Ş. Arslan,et al. Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N-nitrosodimethylamine in kidney and lung. , 2007, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[21] M. Işcan,et al. Stimulatory effects of benzene on rabbit liver and kidney microsomal cytochrome P-450 dependent drug metabolizing enzymes , 2006, Archives of Toxicology.
[22] M. Loriot,et al. Childhood leukaemia, polymorphisms of metabolism enzyme genes, and interactions with maternal tobacco, coffee and alcohol consumption during pregnancy , 2005, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.
[23] A. Bauer,et al. Use of genetically modified mouse models to assess pathways of benzene-induced bone marrow cytotoxicity and genotoxicity. , 2005, Chemico-biological interactions.
[24] Ş. Arslan,et al. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver , 2005, Archives of Toxicology.
[25] N. Özbek. Çocukluk Çağı Akut Lenfoblastik Lösemisi , 2005 .
[26] T. Celkan,et al. NAD(P)H:quinone oxidoreductase 1 null genotype is not associated with pediatric de novo acute leukemia , 2004, Pediatric blood & cancer.
[27] D. Lahiri,et al. DNA isolation by a rapid method from human blood samples: Effects of MgCl2, EDTA, storage time, and temperature on DNA yield and quality , 1993, Biochemical Genetics.
[28] M. Hiltunen,et al. Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are associated with polycystic ovary syndrome. , 2003, Fertility and sterility.
[29] F. Oesch,et al. Detoxification Strategy of Epoxide Hydrolase , 2003 .
[30] F. Oesch,et al. Detoxification Strategy of Epoxide Hydrolase The Basis for a Threshold in Chemical Carcinogenesis , 2003 .
[31] S. Z. Abdel‐Rahman,et al. A model of sensitivity: 1,3‐butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene , 2003, Environmental and molecular mutagenesis.
[32] A. Amorim,et al. The GSTM1 and GSTT1 genetic polymorphisms and susceptibility to acute lymphoblastic leukemia in children from north Portugal , 2002, Leukemia.
[33] I. Hickson,et al. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions , 2001, The EMBO journal.
[34] J. Hoeijmakers. Genome maintenance mechanisms for preventing cancer , 2001, Nature.
[35] M. Weinfeld,et al. XRCC1 Stimulates Human Polynucleotide Kinase Activity at Damaged DNA Termini and Accelerates DNA Single-Strand Break Repair , 2001, Cell.
[36] O. Adalı,et al. Stimulation of aniline, p-nitrophenol and N-nitrosodimethylamine metabolism in kidney by pyridine pretreatment of rabbits , 2000, Archives of Toxicology.
[37] M. Waters,et al. A review of the genetic and related effects of 1,3-butadiene in rodents and humans. , 2000, Mutation research.
[38] O. Adalı,et al. Induction of N-nitrosodimethylamine metabolism in liver and lung by in vivo pyridine treatments of rabbits , 2000, Archives of Toxicology.
[39] M. Ingelman-Sundberg,et al. Genetic epidemiology of environmental toxicity and cancer susceptibility: human allelic polymorphisms in drug-metabolizing enzyme genes, their functional importance, and nomenclature issues. , 1999, Drug metabolism reviews.
[40] D. Bell,et al. XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. , 1999, Cancer research.
[41] D. Labuda,et al. Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. , 1999, Blood.
[42] F. Oesch,et al. Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. , 1998, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[43] D. Harrison,et al. Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema , 1997, The Lancet.
[44] H. Kroemer,et al. Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach. , 1996, Xenobiotica; the fate of foreign compounds in biological systems.
[45] F. Oesch,et al. The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein. , 1994, The Biochemical journal.
[46] J. S. Sidhu,et al. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. , 1994, Human molecular genetics.
[47] A. Sen,et al. Effects of in vivo benzo(a)pyrene treatment on liver microsomal mixed-function oxidase activities of gilthead seabream (Sparus aurata). , 1994, Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology.
[48] J. Potter,et al. Epidemiology of childhood leukemia, with a focus on infants. , 1994, Epidemiologic reviews.
[49] F E Alexander,et al. Parental occupations of children with leukaemia in west Cumbria, north Humberside, and Gateshead. , 1991, BMJ.
[50] M. Ingelman-Sundberg,et al. Benzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes. , 1988, Cancer research.
[51] G. Bellucci,et al. The metabolism of carbamazepine in humans: steric course of the enzymatic hydrolysis of the 10,11-epoxide. , 1987, Journal of medicinal chemistry.
[52] C. Falany,et al. Structure and organization of the microsomal xenobiotic epoxide hydrolase gene. , 1987, The Journal of biological chemistry.
[53] E. Arinç,et al. Preparation and properties of partially purified pulmonary cytochrome P-450 from rabbits. , 1976, The Journal of biological chemistry.
[54] F. Oesch,et al. Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds. , 1973, Xenobiotica; the fate of foreign compounds in biological systems.