Fuzzy anisotropic diffusion based segmentation and texture based ensemble classification of brain tumor

Abstract Brain tumor is one of the major causes of death among other types of the cancers. Proper and timely diagnosis can prevent the life of a person to some extent. Therefore we have proposed an automated reliable system for the diagnosis of the brain tumor. Proposed system is a multi-stage system for brain tumor diagnosis and tumor region extraction. First, noise removal is performed as the preprocessing step on the brain MR images. Texture features are extracted from these noise free brain MR images. Next phase of the proposed system is classification that is based on these extracted features. Ensemble based SVM classification is used. More than 99% accuracy is achieved by the classification phase. After classification, proposed system extracts tumor region from tumorous images using multi-step segmentation. First step is skull removal and brain region extraction. Next step is separating tumor region from normal brain cells using FCM clustering. Results of the proposed technique show that tumor region is extracted quite accurately. This technique has been tested against the datasets of different patients received from Holy Family hospital and Abrar MRI & CT Scan center Rawalpindi.

[1]  Thomas G. Dietterich Multiple Classifier Systems , 2000, Lecture Notes in Computer Science.

[2]  P. V. van Ooijen,et al.  Basic principles of magnetic resonance imaging. , 1999, Progress in cardiovascular diseases.

[3]  Qihao Weng,et al.  A survey of image classification methods and techniques for improving classification performance , 2007 .

[4]  Sung Wook Baik,et al.  Anisotropic Diffusion based Brain MRI Segmentation and 3D Reconstruction , 2012, Int. J. Comput. Intell. Syst..

[5]  Volker Blanz,et al.  Face Recognition Using Component-Based SVM Classification and Morphable Models , 2002, SVM.

[6]  Chengjun Liu,et al.  Gabor feature based classification using the enhanced fisher linear discriminant model for face recognition , 2002, IEEE Trans. Image Process..

[7]  Peggy Woodward MRI for Technologists , 1995 .

[8]  M. Stella Atkins,et al.  Fully automatic segmentation of the brain in MRI , 1998, IEEE Transactions on Medical Imaging.

[9]  Ping Wang,et al.  A Modified FCM Algorithm for MRI Brain Image Segmentation , 2008 .

[10]  Borut Marincek,et al.  How Does MRI Work? An Introduction to the Physics and Function of Magnetic Resonance Imaging , 2007, Journal of Nuclear Medicine.

[11]  Bin Li,et al.  An Improved FCM Algorithm Incorporating Spatial Information for Image Segmentation , 2008, 2008 International Symposium on Computer Science and Computational Technology.

[12]  Stephen M. Smith,et al.  Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm , 2001, IEEE Transactions on Medical Imaging.

[13]  Hai-Yan Yu,et al.  Three-Level Image Segmentation Based on Maximum Fuzzy Partition Entropy of 2-D Histogram and Quantum Genetic Algorithm , 2008, ICIC.

[14]  Alexander J. Smola,et al.  Learning with Kernels: support vector machines, regularization, optimization, and beyond , 2001, Adaptive computation and machine learning series.

[15]  Sanjay Sharma,et al.  Brain Tumor Detection based on Multi-parameter MRI Image Analysis , 2009 .

[16]  Hugo Guterman,et al.  An adaptive neuro-fuzzy system for automatic image segmentation and edge detection , 2002, IEEE Trans. Fuzzy Syst..

[17]  James C. Bezdek,et al.  Pattern Recognition with Fuzzy Objective Function Algorithms , 1981, Advanced Applications in Pattern Recognition.

[18]  Sara Dehghani,et al.  Breast Cancer Diagnosis System Based on Contourlet Analysis and Support Vector Machine , 2011 .

[19]  Joseph Magliano,et al.  Text Categorization for Assessing Multiple Documents Integration, or John Henry Visits a Data Mine , 2011, AIED.

[20]  H. Murao,et al.  A Similarity Measuring Method for Images Based on the Feature Extraction Algorithm using Reference Vectors , 2007, Second International Conference on Innovative Computing, Informatio and Control (ICICIC 2007).

[21]  Nello Cristianini,et al.  Support vector machine classification and validation of cancer tissue samples using microarray expression data , 2000, Bioinform..

[22]  Sumeet Dua,et al.  Associative classification of mammograms using weighted rules , 2009, Expert Syst. Appl..

[23]  Robert M. Haralick,et al.  Textural Features for Image Classification , 1973, IEEE Trans. Syst. Man Cybern..

[24]  Zhencheng Hu,et al.  Face Recognition Based on Dominant Frequency Features and Multiresolution Metric , 2007, Second International Conference on Innovative Computing, Informatio and Control (ICICIC 2007).

[25]  Robert E. Schapire,et al.  The Boosting Approach to Machine Learning An Overview , 2003 .

[26]  Ron Kikinis,et al.  Improved watershed transform for medical image segmentation using prior information , 2004, IEEE Transactions on Medical Imaging.

[27]  Madasu Hanmandlu,et al.  Semi-automatic Segmentation of MRI Brain Tumor , 2009 .

[28]  Laurent Demanet,et al.  Fast Discrete Curvelet Transforms , 2006, Multiscale Model. Simul..

[29]  Sanghamitra Bandyopadhyay,et al.  MRI brain image segmentation by fuzzy symmetry based genetic clustering technique , 2007, 2007 IEEE Congress on Evolutionary Computation.

[30]  Alan C. Evans,et al.  A fully automatic and robust brain MRI tissue classification method , 2003, Medical Image Anal..

[31]  Michal Strzelecki,et al.  Texture Analysis Methods - A Review , 1998 .