Studies on the glomerular filtration rate of rainbow trout (Salmo gairdneri).

1. Variations in the glomerular filtration rate (G.F.R.) and the renal tubular reabsorption of water are probably important factors in the homoiostatic mechanisms associated with the euryhalinity of the rainbow trout ( Salmo gairdneri ). 2. The observed reduction in urine flow after the adaptation of rainbow trout to sea water can be largely accounted for on the basis of the reduced G.F.R. 3. Intraperitoneal injections of mammalian preparations of vasopressin, oxytocin and vasopressin/oxytocin into freshwater trout significantly increased the G.F.R. 4. The intraperitoneal injection of aldosterone into freshwater fish had no detectable effect on G.F.R. 5. The similar administration of corticosterone significantly reduced the G.F.R. to 73% of the intact freshwater control value. This work was supported by grants to one of us (W. N. H.) from the National Research Council of Canada and the U.S. Atomic Energy Commission (Contract no. AT (45-1) 1381).

[1]  W. N. Holmes,et al.  Effects of adrenocortical and neurohypophysial hormones on the renal excretory pattern in the water-loaded duck (Anas platyrhynchols). , 1963, Endocrinology.

[2]  I. Carlson,et al.  Changes in the hormone content of the hypothalamo-hypophysial system of the rainbow trout (Salmo gairdneri). , 1962, The Journal of endocrinology.

[3]  A. Houston.  Variations in the Plasma-Level of Chloride in Hatchery-reared Yearling Atlantic Salmon during Parr–Smolt Transformation and following Transfer into Sea-Water , 1960, Nature.

[4]  A. Houston.  OSMOREGULATORY ADAPTATION OF STEELHEAD TROUT (SALMO GAIRDNERI RICHARDSON) TO SEA WATER , 1959 .

[5]  W. N. Holmes.  Studies on the hormonal control of sodium metabolism in the rainbow trout (Salmo gairdneri). , 1959, Acta endocrinologica.

[6]  J. P. Peters,et al.  The Kidney, Structure and Function in Health and Disease , 1952, The Yale Journal of Biology and Medicine.

[7]  G. Schreiner,et al.  Determination of Inulin by Means of Resorcinol , 1950, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[8]  N. Goldstein,et al.  A photometric method for the determination of insulin in plasma and urine. , 1949, The Journal of biological chemistry.

[9]  H. W. Smith,et al.  THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN. , 1945, The Journal of clinical investigation.

[10]  L. F. Nims.  Osmotic Regulation in Aquatic Animals , 1939, The Yale Journal of Biology and Medicine.

[11]  E. Adolph.  CONTROL OF URINE FORMATION IN THE FROG BY THE RENAL CIRCULATION , 1936 .

[12]  A. M. Harvey,et al.  THE SITE OF THE ANTIDIURETIC ACTION OF PITUITARY EXTRACT , 1933 .

[13]  J. Nash.  The number and size of glomeruli in the kidneys of fishes, with observations on the morphology of the renal tubules of fishes , 1931 .

[14]  Homer W. Smith.  THE ABSORPTION AND EXCRETION OF WATER AND SALTS BY MARINE TELEOSTS , 1930 .

[15]  C. Schmidt,et al.  A DESCRIPTION OF THE GLOMERULAR CIRCULATION IN THE FROG'S KIDNEY AND OBSERVATIONS CONCERNING THE ACTION OF ADRENALIN AND VARIOUS OTHER SUBSTANCES UPON IT , 1924 .

[16]  B. Pickering,et al.  Neurohypophysial hormones of non‐mammalian vertebrates , 1961, The Journal of physiology.

[17]  V. Columbia.  STUDIES ON THE DEVELOPMENT OF THE KIDNEY OF THE PACIFIC PINK SALMON, (ONCORHYNCHUS GORBUSCHA (WALBAUM)) , 1958 .