Physiology and electrical activity of uterine contractions.

Presently, there is no effective treatment for preterm labor. The most obvious reason for this anomaly is that there is no objective manner to evaluate the progression of pregnancy through steps leading to labor, either at term or preterm. Several techniques have been adopted to monitor labor, and/or to diagnose labor, but they are either subjective or indirect, and they do not provide an accurate prediction of when labor will occur. With no method to determine preterm labor, treatment might never improve. Uterine electromyography (EMG) methods may provide such needed diagnostics.

[1]  B. Blondel,et al.  [The length of the cervix and the risk of spontaneous premature delivery]. , 1996, Revue d'epidemiologie et de sante publique.

[2]  S. Lye,et al.  Understanding Preterm Labor , 2001, Annals of the New York Academy of Sciences.

[3]  C. Lockwood.  Biochemical predictors of prematurity. , 2001, Frontiers of hormone research.

[4]  S. Arulkumaran,et al.  Potassium Channels in the Human Myometrium , 2001, Experimental physiology.

[5]  Muriel Doret,et al.  Uterine Electromyography Characteristics for Early Diagnosis of Mifepristone-Induced Preterm Labor , 2005, Obstetrics and gynecology.

[6]  K. Oláh.  Changes in cervical electromyographic activity and their correlation with the cervical response to myometrial activity during labour. , 1994, European journal of obstetrics, gynecology, and reproductive biology.

[7]  G. Cutter,et al.  Cervical examination and tocodynamometry at 28 weeks' gestation: prediction of spontaneous preterm birth. , 1995, American journal of obstetrics and gynecology.

[8]  Yallampalli Chandra,et al.  Control of Myometrial Contractility and Labor , 1994 .

[9]  T. Goodwin,et al.  Salivary estriol as risk assessment for preterm labor: a prospective trial. , 1995, American journal of obstetrics and gynecology.

[10]  R. Naguib,et al.  Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management , 2000 .

[11]  E. Bülbring.  Smooth Muscle: An Assessment of Current Knowledge , 1982 .

[12]  H. Coleman,et al.  Excitability in uterine smooth muscle. , 2001, Frontiers of hormone research.

[13]  J. Marshall,et al.  Activity of circular muscle of rat uterus at different times in pregnancy. , 1984, The American journal of physiology.

[14]  P. Stubblefield,et al.  Preterm birth: Causes, prevention, and management , 1984 .

[15]  Armstrong Ma,et al.  Monitoring women at risk for preterm labor , 1998 .

[16]  J. Marshall,et al.  Effects of estrogen and progesterone on single uterine muscle fibers in the rat. , 1959, The American journal of physiology.

[17]  G. Saade,et al.  Predicting Term and Preterm Delivery With Transabdominal Uterine Electromyography , 2003, Obstetrics and gynecology.

[18]  Marshall Jm,et al.  Regulation of activity in uterine smooth muscle. , 1962 .

[19]  Ralph M. Wynn,et al.  Biology of the Uterus , 2012, Springer US.

[20]  D. Harper.  MONITORING WOMEN AT RISK FOR PRETERM LABOR. , 1998 .

[21]  T. Osa,et al.  Effects of magnesium, oxytocin, and prostaglandin F2 alpha on the generation and propagation of excitation in the longitudinal muscle of rat myometrium during late pregnancy. , 1983, The Japanese journal of physiology.

[22]  J. P. Morucci,et al.  External recording and processing of fast electrical activity of the uterus in human parturition , 1984, Medical and Biological Engineering and Computing.

[23]  G. Wolfs,et al.  Electrical and mechanical activity of the human uterus during labour , 1970, Archiv für Gynäkologie.

[24]  T. Kawarabayashi.  The effects of phenylephrine in various ionic environments on the circular muscle of mid-pregnant rat myometrium. , 1978, The Japanese journal of physiology.

[25]  T. Zakar,et al.  Prostaglandins and the myometrium and cervix. , 2004, Prostaglandins, leukotrienes, and essential fatty acids.

[26]  Catherine Marque,et al.  Analyzing uterine EMG: tracking instantaneous burst frequency , 1995 .

[27]  J. Iams,et al.  Prediction and early detection of preterm labor. , 2003, Obstetrics and gynecology.

[28]  A. Holden,et al.  Endogenous driving and synchronization in cardiac and uterine virtual tissues: bifurcations and local coupling , 2006, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[29]  G. Saade,et al.  Non-invasive transabdominal uterine electromyography correlates with the strength of intrauterine pressure and is predictive of labor and delivery , 2004, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[30]  Kao Cy.  Long-term observations of spontaneous electrical activity of the uterine smooth muscle. , 1959 .

[31]  William L. Maner,et al.  Characterization of abdominally acquired uterine electrical signals in humans, using a non-linear analytic method , 2006, Medical and Biological Engineering and Computing.

[32]  G. Saade,et al.  Prediction of term and preterm parturition and treatment monitoring by measurement of cervical cross‐linked collagen using light‐induced fluorescence , 2005, Acta obstetricia et gynecologica Scandinavica.

[33]  U. P. S. T. Force,et al.  Guide to clinical preventive services : an assessment of the effectiveness of 169 interventions : report of the U.S. Preventive Services Task Force , 1989 .

[34]  R. Garfield,et al.  Basic Mechanisms Controlling Term and Preterm Birth , 2013, Ernst Schering Research Foundation Workshop.

[35]  Susan Wray,et al.  Vimentin-Positive, c-KIT-Negative Interstitial Cells in Human and Rat Uterus: A Role in Pacemaking?1 , 2005, Biology of reproduction.

[36]  C Marque,et al.  Uterine electromyography: a critical review. , 1993, American journal of obstetrics and gynecology.

[37]  S. Wray,et al.  Ca2+ entry, efflux and release in smooth muscle. , 2004, Biological research.

[38]  H. Parkington,et al.  Relaxin inhibits the plateau component of the action potential in the circular myometrium of the rat. , 1984, The Journal of physiology.

[39]  M. F. Block.  Principles and Practice of Obstetrics and Perinatology , 1982 .

[40]  William L. Maner,et al.  Identification of Human Term and Preterm Labor using Artificial Neural Networks on Uterine Electromyography Data , 2007, Annals of Biomedical Engineering.

[41]  D. Kumar,et al.  Studies in human myometrium during pregnancy , 1961 .

[42]  R. Garfield,et al.  Electrical Activity of the Human Uterus During Pregnancy as Recorded from the Abdominal Surface , 1997, Obstetrics and gynecology.

[43]  A. Shafik.  Electrohysterogram: study of the electromechanical activity of the uterus in humans. , 1997, European journal of obstetrics, gynecology, and reproductive biology.

[44]  Fetal fibronectin detection for prediction of preterm birth in low risk women , 1995, British journal of obstetrics and gynaecology.