Enhanced production of aspochalasin D through genetic engineering of Aspergillus flavipes

[1]  Huiling Liu,et al.  Stimulating fungal cell wall integrity by exogenous β-glucanase to improve the production of fungal natural products , 2022, Applied Microbiology and Biotechnology.

[2]  Yijun Yan,et al.  Discovery of the Biosynthetic Pathway of Beticolin 1 Reveals a Novel Non-heme Iron-dependent Oxygenase for Anthraquinone Ring Cleavage. , 2022, Angewandte Chemie.

[3]  Jinmei Zhang,et al.  Berberine bridge enzyme-like oxidase-catalysed double bond isomerization acts as the pathway switch in cytochalasin synthesis , 2022, Nature communications.

[4]  N. Keller,et al.  Transcription Factor Repurposing Offers Insights into Evolution of Biosynthetic Gene Cluster Regulation , 2021, mBio.

[5]  T. Zhou,et al.  Enhanced cercosporin production by co-culturing Cercospora sp. JNU001 with leaf-spot-disease-related endophytic bacteria , 2021, Microbial Cell Factories.

[6]  C. Thawai,et al.  Functional analysis of a chaetoglobosin A biosynthetic regulator in Chaetomium globosum. , 2020, Fungal biology.

[7]  R. Cox,et al.  Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans , 2020, Chemistry.

[8]  Jianying Luo,et al.  Bisaspochalasins A-C: Three Cytochalasan Homodimers with Highly Fused Ring System from an Endophytic Aspergillus flavipes. , 2020, Organic letters.

[9]  Jaclyn M. Winter,et al.  Discovery and characterization of a cytochalasan biosynthetic cluster from the marine-derived fungus Aspergillus flavipes CNL-338 , 2020, The Journal of Antibiotics.

[10]  R. Cox,et al.  Evidence for enzyme catalysed intramolecular [4+2] Diels-Alder cyclization during the biosynthesis of pyrichalasin H. , 2020, Chemical communications.

[11]  Yinhua Lu,et al.  Recent Advances in Synthetic Biology Approaches to Optimize Production of Bioactive Natural Products in Actinobacteria , 2019, Front. Microbiol..

[12]  R. Cox,et al.  Function of pathway specific regulators in the ACE1 and pyrichalasin H biosynthetic gene clusters , 2019, RSC advances.

[13]  R. Cox,et al.  Investigating the Function of Cryptic Cytochalasan Cytochrome P450 Monooxygenases Using Combinatorial Biosynthesis. , 2019, Organic letters.

[14]  Elizabeth J. Skellam.  Strategies for Engineering Natural Product Biosynthesis in Fungi. , 2019, Trends in biotechnology.

[15]  B. Shen,et al.  Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts , 2019, Journal of Industrial Microbiology & Biotechnology.

[16]  N. Keller.  Fungal secondary metabolism: regulation, function and drug discovery , 2018, Nature Reviews Microbiology.

[17]  D. Trauner,et al.  Biomimetic Synthesis of (+)-Aspergillin PZ. , 2018, Angewandte Chemie.

[18]  Wan-jing Ding,et al.  Two Novel Aspochalasins from the Gut Fungus Aspergillus sp. Z4 , 2018, Marine drugs.

[19]  Elizabeth J. Skellam.  The biosynthesis of cytochalasans. , 2017, Natural product reports.

[20]  Yonghui Zhang,et al.  Asperflavipine A: A Cytochalasan Heterotetramer Uniquely Defined by a Highly Complex Tetradecacyclic Ring System from Aspergillus flavipes QCS12. , 2017, Angewandte Chemie.

[21]  Xuewei Wang,et al.  Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. , 2016, Journal of natural products.

[22]  Inhyung Lee,et al.  Overexpression of the laeA gene leads to increased production of cyclopiazonic acid in Aspergillus fumisynnematus. , 2015, Fungal biology.

[23]  R. Cox,et al.  Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae , 2015, Chemical science.

[24]  J. Vederas,et al.  A Carbonate-Forming Baeyer-Villiger Monooxygenase , 2014, Nature chemical biology.

[25]  Hong-wu Zhang,et al.  Trichodermone, a spiro-cytochalasan with a tetracyclic nucleus (7/5/6/5) skeleton from the plant endophytic fungus Trichoderma gamsii. , 2014, Journal of natural products.

[26]  A. Minami,et al.  Biosynthetic assembly of cytochalasin backbone , 2013 .

[27]  C. Shao,et al.  Bioactive Phenylalanine Derivatives and Cytochalasins from the Soft Coral-Derived Fungus, Aspergillus elegans , 2013, Marine drugs.

[28]  Xingzhong Liu,et al.  Trichalasins C and D from the plant endophytic fungus Trichoderma gamsii. , 2012, Fitoterapia.

[29]  Y. Chooi,et al.  Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1. , 2011, Metabolic engineering.

[30]  C. Hertweck,et al.  The chemistry and biology of cytochalasans. , 2010, Natural product reports.

[31]  Hong Wei,et al.  Spicochalasin A and New Aspochalasins from the Marine-Derived Fungus Spicaria elegans. , 2009 .

[32]  Hong Wei,et al.  Spicochalasin A and New Aspochalasins from the Marine‐Derived Fungus Spicaria elegans , 2009 .

[33]  L. Pierson,et al.  Aspochalasins I, J, and K: three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran Desert. , 2004, Journal of natural products.

[34]  K. Shin‐ya,et al.  Selective cytotoxicity and stereochemistry of aspochalasin D. , 2001, The Journal of antibiotics.

[35]  S. Brown,et al.  Mechanism of action of cytochalasin: evidence that it binds to actin filament ends , 1981, The Journal of cell biology.

[36]  C. Tamm,et al.  Isolation and structure of Phomin , 1966, Experientia.

[37]  R. Teshima,et al.  Effects of various cytochalasins on the IgE-mediated serotonin release from rat basophilic leukemia cells. , 1985, International archives of allergy and applied immunology.