Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion

[1]  H. Nakshatri,et al.  Negative regulation of MHC class II gene expression by CXCR4. , 2006, Experimental hematology.

[2]  A. Baccarelli,et al.  The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study , 2006, Breast Cancer Research and Treatment.

[3]  M. Locati,et al.  Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness. , 2005, Experimental cell research.

[4]  David P Lane,et al.  p53 isoforms can regulate p53 transcriptional activity. , 2005, Genes & development.

[5]  S. Shimizu,et al.  Regulation of neuronal P53 activity by CXCR4 , 2005, Molecular and Cellular Neuroscience.

[6]  M. Ratajczak,et al.  Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of the SDF‐1–CXCR4 Axis , 2005, Stem cells.

[7]  P. Brandt-Rauf,et al.  Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway , 2005, Molecular Cancer Therapeutics.

[8]  A. Usheva,et al.  Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration. , 2005, Cancer research.

[9]  T. Yamano,et al.  Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. , 2005, Cancer research.

[10]  J. Votaw,et al.  Silencing of CXCR4 blocks breast cancer metastasis. , 2005, Cancer research.

[11]  D. Piwnica-Worms,et al.  CXCR4 Regulates Growth of Both Primary and Metastatic Breast Cancer , 2004, Cancer Research.

[12]  M. Scian,et al.  Modulation of Gene Expression by Tumor-Derived p53 Mutants , 2004, Cancer Research.

[13]  F. Balkwill.  Cancer and the chemokine network , 2004, Nature Reviews Cancer.

[14]  G. Firestein,et al.  p53 down‐regulates matrix metalloproteinase‐1 by targeting the communications between AP‐1 and the basal transcription complex , 2004, Journal of cellular biochemistry.

[15]  S. Lowe,et al.  Control of apoptosis by p53 , 2003, Oncogene.

[16]  Erwin G. Van Meir,et al.  Tumor suppressor p53 inhibits transcriptional activation of invasion gene thromboxane synthase mediated by the proto-oncogenic factor ets-1 , 2003, Oncogene.

[17]  Barry Komm,et al.  Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. , 2003, Endocrinology.

[18]  H. Moch,et al.  Chemokine receptor CXCR4 downregulated by von Hippel–Lindau tumour suppressor pVHL , 2003, Nature.

[19]  H. Nakshatri,et al.  NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4* , 2003, Journal of Biological Chemistry.

[20]  C. Cordon-Cardo,et al.  A multigenic program mediating breast cancer metastasis to bone. , 2003, Cancer cell.

[21]  R. Bachelder,et al.  Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. , 2002, Cancer research.

[22]  Galina Selivanova,et al.  Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database. , 2002, Carcinogenesis.

[23]  Xin Lu,et al.  Live or let die: the cell's response to p53 , 2002, Nature Reviews Cancer.

[24]  Yan Dong,et al.  Molecular mechanism of transcriptional repression of gelsolin in human breast cancer cells. , 2002, Experimental cell research.

[25]  M. Karin,et al.  AP-1 as a regulator of cell life and death , 2002, Nature Cell Biology.

[26]  Galina Selivanova,et al.  Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound , 2002, Nature Medicine.

[27]  K. Kinzler,et al.  Targeted inactivation of p53 in human cells does not result in aneuploidy. , 2002, Cancer research.

[28]  Marc Montminy,et al.  Transcriptional regulation by the phosphorylation-dependent factor CREB , 2001, Nature Reviews Molecular Cell Biology.

[29]  Kuan-Teh Jeang,et al.  CREB/ATF-Dependent Repression of Cyclin A by Human T-Cell Leukemia Virus Type 1 Tax Protein , 2001, Journal of Virology.

[30]  T. Mcclanahan,et al.  Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.

[31]  R. Vossen,et al.  Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer. , 2000, Cancer research.

[32]  B. Foster,et al.  Pharmacological rescue of mutant p53 conformation and function. , 1999, Science.

[33]  A. Fauci,et al.  USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for HIV-1 entry. , 1999, Journal of immunology.

[34]  M. Parmentier,et al.  Genomic organization and promoter characterization of human CXCR4 gene 1 , 1998, FEBS letters.

[35]  A. Chicas,et al.  p53 represses Sp1 DNA binding and HIV-LTR directed transcription. , 1997, Cellular and molecular biology.

[36]  B. Vogelstein,et al.  Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. , 1991, Oncogene.

[37]  A. Sahin,et al.  Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow , 2005, Clinical & Experimental Metastasis.

[38]  W. Gerald,et al.  Identifying site-specific metastasis genes and functions. , 2005, Cold Spring Harbor symposia on quantitative biology.