Arrhythmogenecity and thrombogenicity of the residual left atrial appendage stump following surgical exclusion of the appendage in patients with atrial fibrillation

It is common to find residual stump after the amputation or clip exclusion of the left atrial appendage (LAA). We evaluated the arrhythmogenic and thrombogenic potential of LAA stumps in atrial fibrillation (AF) patients.

[1]  R. Petr,et al.  Residual echocardiographic and computed tomography findings after thoracoscopic occlusion of the left atrial appendage using the AtriClip PRO device. , 2018, Interactive cardiovascular and thoracic surgery.

[2]  Yan Wang,et al.  Sustained localized reentry within the left atrial appendage as a mechanism of recurrent arrhythmia following atrial fibrillation ablation , 2018, Experimental and therapeutic medicine.

[3]  M. Alkhouli,et al.  Oral anticoagulation may not be necessary for patients discharged in sinus rhythm after the Cox Maze IV procedure , 2017, The Journal of thoracic and cardiovascular surgery.

[4]  L. Di Biase,et al.  Role of the left atrial appendage “stump” in persistent atrial fibrillation , 2017, HeartRhythm case reports.

[5]  N. Ad,et al.  Minimally Invasive Stand-Alone Cox Maze Procedure for Persistent and Long-Standing Persistent Atrial Fibrillation: Perioperative Safety and 5-Year Outcomes , 2017, Circulation. Arrhythmia and electrophysiology.

[6]  A. Natale,et al.  Procedural findings and ablation outcome in patients with atrial fibrillation referred after two or more failed catheter ablations , 2017, Journal of cardiovascular electrophysiology.

[7]  Frederick T. Han,et al.  Long-term outcomes of minimally invasive surgical ablation for atrial fibrillation: A single-center experience. , 2017, Heart rhythm.

[8]  Dhanunjaya R. Lakkireddy,et al.  Atrial Tachycardias After Surgical Atrial Fibrillation Ablation: Clinical Characteristics, Electrophysiological Mechanisms, and Ablation Outcomes From a Large, Multicenter Study. , 2017, JACC. Clinical electrophysiology.

[9]  P. Zeman,et al.  Epicardial clip occlusion of the left atrial appendage during cardiac surgery provides optimal surgical results and long-term stability. , 2017, Interactive cardiovascular and thoracic surgery.

[10]  M. Chung,et al.  2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation , 2017, Heart rhythm.

[11]  A. Aryana,et al.  Incomplete surgical ligation of the left atrial appendage-time for a new look at an old problem. , 2017, Annals of translational medicine.

[12]  S. Themistoclakis,et al.  Left Atrial Appendage Isolation in Patients With Longstanding Persistent AF Undergoing Catheter Ablation: BELIEF Trial. , 2016, Journal of the American College of Cardiology.

[13]  P. McCarthy,et al.  A randomized, prospective pilot comparison of 3 atrial appendage elimination techniques: Internal ligation, stapled excision, and surgical excision. , 2016, The Journal of thoracic and cardiovascular surgery.

[14]  E. Pokushalov,et al.  Effect of left atrial appendage excision on procedure outcome in patients with persistent atrial fibrillation undergoing surgical ablation. , 2016, Heart rhythm.

[15]  R. Virmani,et al.  Left Atrial Appendage Electrical Isolation and Concomitant Device Occlusion to Treat Persistent Atrial Fibrillation: A First-in-Human Safety, Feasibility, and Efficacy Study , 2016, Circulation. Arrhythmia and electrophysiology.

[16]  Y. Liao,et al.  Intensity of Left Atrial Spontaneous Echo Contrast as a Correlate for Stroke Risk Stratification in Patients with Nonvalvular Atrial Fibrillation , 2016, Scientific Reports.

[17]  M. Price,et al.  Clinical Implications of Leaks Following Left Atrial Appendage Ligation With the LARIAT Device. , 2016, JACC. Cardiovascular interventions.

[18]  V. Reddy,et al.  Left Atrial Appendage and Closure: Who, When, and How. , 2016, Circulation. Cardiovascular interventions.

[19]  S. Choo,et al.  Long-Term Outcomes of the Maze Procedure Combined With Mitral Valve Repair: Risk of Thromboembolism Without Anticoagulation Therapy. , 2015, The Annals of thoracic surgery.

[20]  S. Themistoclakis,et al.  Pulmonary Vein Isolation to Reduce Future Risk of Atrial Fibrillation in Patients Undergoing Typical Flutter Ablation: Results from a Randomized Pilot Study (REDUCE AF) , 2015, Journal of cardiovascular electrophysiology.

[21]  S. Asirvatham,et al.  A Review Of The Relevant Embryology, Pathohistology, And Anatomy Of The Left Atrial Appendage For The Invasive Cardiac Electrophysiologist. , 2015, Journal of atrial fibrillation.

[22]  A. Natale,et al.  Left Atrial Appendage Ligation and Ablation for Persistent Atrial Fibrillation: The LAALA-AF Registry. , 2015, JACC. Clinical electrophysiology.

[23]  E. Kretov,et al.  Does left atrial appendage closure improve the success of pulmonary vein isolation? Results of a randomized clinical trial , 2015, Journal of Interventional Cardiac Electrophysiology.

[24]  R. Damiano,et al.  Surgical ablation for atrial fibrillation: techniques, indications, and results , 2015, Current opinion in cardiology.

[25]  Reza Arsanjani,et al.  The left atrial appendage: anatomy, function, and noninvasive evaluation. , 2014, JACC. Cardiovascular imaging.

[26]  J. Kasprzak,et al.  Prognostic significance of spontaneous echocardiographic contrast detected by transthoracic and transesophageal echocardiography in the era of harmonic imaging , 2013, Archives of medical science : AMS.

[27]  A. Massumi,et al.  Initial experience with a novel percutaneous left atrial appendage exclusion device in patients with atrial fibrillation, increased stroke risk, and contraindications to anticoagulation. , 2013, The American journal of cardiology.

[28]  R. Kasliwal,et al.  Echocardiography for left atrial appendage structure and function. , 2012, Indian heart journal.

[29]  Ashok J. Shah,et al.  Localized reentry within the left atrial appendage: arrhythmogenic role in patients undergoing ablation of persistent atrial fibrillation. , 2011, Heart rhythm.

[30]  Sanghamitra Mohanty,et al.  Left Atrial Appendage: An Underrecognized Trigger Site of Atrial Fibrillation , 2010, Circulation.

[31]  P. Vardas,et al.  Mechanisms of Arrhythmia Recurrence After Video‐Assisted Thoracoscopic Surgery for the Treatment of Atrial Fibrillation: Insights from Electrophysiological Mapping and Ablation , 2009, Cardiovascular Electrophysiology.

[32]  J. Healey,et al.  Left Atrial Appendage Occlusion Does Not Eliminate the Need for Warfarin , 2009, Circulation.

[33]  J. Dodd,et al.  Ectopic focus in an accessory left atrial appendage: radiofrequency ablation of refractory atrial fibrillation. , 2009, Circulation.

[34]  E. Blackstone,et al.  Success of surgical left atrial appendage closure: assessment by transesophageal echocardiography. , 2008, Journal of the American College of Cardiology.

[35]  G. Kay,et al.  Electrophysiologic and electrocardiographic characteristics and radiofrequency catheter ablation of focal atrial tachycardia originating from the left atrial appendage. , 2007, Heart rhythm.

[36]  I. Black.  Spontaneous Echo Contrast: Where There's Smoke There's Fire , 2000, Echocardiography.

[37]  R. Hauer,et al.  Abnormal Automaticity as Mechanism of Atrial Tachycardia in the Human Heart—Electrophysiologic and Histologic Correlation: , 1994, Journal of cardiovascular electrophysiology.

[38]  S. Bolling,et al.  The Society of Thoracic Surgeons 2017 Clinical Practice Guidelines for the Surgical Treatment of Atrial Fibrillation. , 2017, The Annals of thoracic surgery.

[39]  O. Alfieri,et al.  Electrophysiological findings and long-term outcomes of percutaneous ablation of atrial arrhythmias after surgical ablation for atrial fibrillation†. , 2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[40]  H. Alkadhi,et al.  Safe, effective and durable epicardial left atrial appendage clip occlusion in patients with atrial fibrillation undergoing cardiac surgery: first long-term results from a prospective device trial. , 2014, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[41]  Y. Hashizume,et al.  Successful surgical treatment of left atrial tachycardia. , 1985, American heart journal.