382: β2 Intergrins Separates Graft-versus-host Disease and Graft-versus-leukemia Effect

[1]  C. Abraham,et al.  CD18 Is Required for Intestinal T Cell Responses at Multiple Immune Checkpoints1 , 2007, The Journal of Immunology.

[2]  Chen Dong,et al.  Opposing Effects of ICOS on Graft-versus-Host Disease Mediated by CD4 and CD8 T Cells1 , 2006, The Journal of Immunology.

[3]  E. Butcher,et al.  Short-term homing assay reveals a critical role for lymphocyte function-associated antigen-1 in the hepatic recruitment of lymphocytes in graft-versus-host disease. , 2006, Journal of hepatology.

[4]  C. Anasetti,et al.  T regulatory cells as an immunotherapy for transplantation , 2006, Expert opinion on biological therapy.

[5]  C. Anasetti,et al.  Alloantigen Affinity and CD4 Help Determine Severity of Graft-versus-Host Disease Mediated by CD8 Donor T Cells1 , 2006, The Journal of Immunology.

[6]  D. Ostanin,et al.  Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis. , 2006, International immunology.

[7]  C. Abraham,et al.  CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells1 , 2005, The Journal of Immunology.

[8]  G. Bumgardner,et al.  Targeting LFA-1 and CD154 Suppresses the In Vivo Activation and Development of Cytolytic (CD4-Independent) CD8+ T Cells12 , 2005, The Journal of Immunology.

[9]  P. Ward,et al.  A Role for CD54 (Intercellular Adhesion Molecule-1) in Leukocyte Recruitment to the Lung During the Development of Experimental Idiopathic Pneumonia Syndrome , 2005, Transplantation.

[10]  A. Gebert,et al.  Naive, Effector, and Memory T Lymphocytes Efficiently Scan Dendritic Cells In Vivo: Contact Frequency in T Cell Zones of Secondary Lymphoid Organs Does Not Depend on LFA-1 Expression and Facilitates Survival of Effector T Cells1 , 2005, The Journal of Immunology.

[11]  C. Anasetti,et al.  CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. , 2004, The Journal of clinical investigation.

[12]  Y. Shimizu,et al.  Integrins and T cell-mediated immunity. , 2004, Annual review of immunology.

[13]  N. Chao,et al.  Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. , 2004, Blood.

[14]  Werner Müller,et al.  CD4+ T Cell-Associated Pathophysiology Critically Depends on CD18 Gene Dose Effects in a Murine Model of Psoriasis 1 , 2003, The Journal of Immunology.

[15]  C. Fathman,et al.  CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation , 2003, Nature Medicine.

[16]  Michael Loran Dustin,et al.  The immunological synapse: integrins take the stage , 2002, Immunological reviews.

[17]  Jiang Zhu,et al.  Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease. , 2002, The Journal of clinical investigation.

[18]  G. Pendl,et al.  Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells. , 2002, The Journal of clinical investigation.

[19]  I. Y. Haddad,et al.  Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplantation. , 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[20]  F. Appelbaum,et al.  Haematopoietic cell transplantation as immunotherapy , 2001, Nature.

[21]  Li Zhang,et al.  Ligand Binding to Integrins* , 2000, The Journal of Biological Chemistry.

[22]  F. Bendjelloul,et al.  Intercellular adhesion molecule‐1 (ICAM‐1) deficiency protects mice against severe forms of experimentally induced colitis , 2000, Clinical and experimental immunology.

[23]  N. Chao,et al.  Pathophysiologic mechanisms of acute graft-vs.-host disease. , 1999, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[24]  M. V. D. van den Brink,et al.  IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation. , 1999, The Journal of clinical investigation.

[25]  A. Beaudet,et al.  Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice , 1998, The Journal of experimental medicine.

[26]  T. Mak,et al.  Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. , 1997, Immunity.

[27]  L. Lefrançois,et al.  Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment. , 1996, Immunity.

[28]  G. Gray,et al.  Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts. , 1995, Blood.

[29]  D. Blanchard,et al.  Restoration of lytic function in a human natural killer cell line by gene transfection. , 1994, Cellular immunology.

[30]  C. Meijer,et al.  Induction of homotypic T cell adhesion by triggering of leukocyte function‐associated antigen‐1α (CD11a): differential effects on resting and activated T cells , 1992, European journal of immunology.

[31]  M. Isobe,et al.  Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. , 1992, Science.

[32]  F. Takei,et al.  REDUCTION IN THE SEVERITY OF GRAFT‐VERSUS-HOST DISEASE AND INCREASED SURVIVAL IN ALLOGENEIC MICE BY TREATMENT WITH MONOCLONAL ANTIBODIES TO CELL ADHESION ANTIGENS LFA‐lα AND MALA‐2 , 1991, Transplantation.

[33]  T. Springer,et al.  Heterogeneous mutations in the β subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency , 1987, Cell.

[34]  G. Murphy,et al.  Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease. , 1986, The Journal of investigative dermatology.

[35]  E. Scarpini,et al.  RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. , 2004, Immunity.