Opening Up the Optical Imaging Window Using Nano-Luciferin

[1]  K. Chopra,et al.  Curcumin loaded solid lipid nanoparticles: an efficient formulation approach for cerebral ischemic reperfusion injury in rats. , 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[2]  E. Alsberg,et al.  Imaging early stage osteogenic differentiation of mesenchymal stem cells , 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[3]  B. Connolly,et al.  Visualization of Mitotic Arrest of Cell Cycle with Bioluminescence Imaging in Living Animals , 2013, Molecular Imaging and Biology.

[4]  F. Ahmad,et al.  Nanocarrier based formulation of Thymoquinone improves oral delivery: stability assessment, in vitro and in vivo studies. , 2013, Colloids and surfaces. B, Biointerfaces.

[5]  Qiang Zhang,et al.  Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. , 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[6]  Christian E Badr,et al.  Bioluminescence imaging: progress and applications. , 2011, Trends in biotechnology.

[7]  Ning Zhang,et al.  Monitoring tumor metastases and osteolytic lesions with bioluminescence and micro CT imaging. , 2011, Journal of visualized experiments : JoVE.

[8]  Bhupinder Singh,et al.  Developing micro-/nanoparticulate drug delivery systems using “design of experiments” , 2011, International journal of pharmaceutical investigation.

[9]  A. Guermazi,et al.  Gastroenteropancreatic neuroendocrine tumors: multimodality imaging features with pathological correlation , 2011, Japanese Journal of Radiology.

[10]  R. Patlolla,et al.  Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[11]  Katherine W Ferrara,et al.  Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[12]  P. Lassota,et al.  A Spontaneous Acinar Cell Carcinoma Model for Monitoring Progression of Pancreatic Lesions and Response to Treatment Through Noninvasive Bioluminescence Imaging , 2009, Clinical Cancer Research.

[13]  S. Gambhir,et al.  Molecular Imaging of Phosphorylation Events for Drug Development , 2009, Molecular Imaging and Biology.

[14]  Kshitij D Modi,et al.  In vivo Bioluminescent Imaging of Mammary Tumors Using IVIS Spectrum , 2009, Journal of visualized experiments : JoVE.

[15]  C. Ling,et al.  Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia. , 2009, Neoplasia.

[16]  Lawrence H. Schwartz,et al.  Imaging Surrogates of Tumor Response to Therapy: Anatomic and Functional Biomarkers* , 2009, Journal of Nuclear Medicine.

[17]  J. Pardeike,et al.  Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. , 2009, International journal of pharmaceutics.

[18]  S. Gambhir,et al.  Uptake kinetics and biodistribution of 14C-d-luciferin—a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging , 2008, European Journal of Nuclear Medicine and Molecular Imaging.

[19]  J. Willmann,et al.  Molecular imaging in drug development , 2008, Nature Reviews Drug Discovery.

[20]  L. Rizza,et al.  Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation. , 2008, International journal of pharmaceutics.

[21]  Weibo Cai,et al.  Multimodality Molecular Imaging of Tumor Angiogenesis , 2008, Journal of Nuclear Medicine.

[22]  E. Reiman,et al.  Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias , 2008, Journal of Nuclear Medicine.

[23]  R. Hargreaves,et al.  The Role of Molecular Imaging in Drug Discovery and Development , 2008, Clinical pharmacology and therapeutics.

[24]  R. Coleman,et al.  The National Oncologic PET Registry (NOPR): Design and Analysis Plan , 2007, Journal of Nuclear Medicine.

[25]  S. Moore,et al.  Clinical Myocardial Perfusion PET/CT* , 2007, Journal of Nuclear Medicine.

[26]  Zhirong Zhang,et al.  Lung-targeting delivery of dexamethasone acetate loaded solid lipid nanoparticles , 2007, Archives of pharmacal research.

[27]  E. Herzog,et al.  Continuous Delivery of D-Luciferin by Implanted Micro-osmotic Pumps Enables True Real-Time Bioluminescence Imaging of Luciferase Activity in Vivo , 2007, Molecular imaging.

[28]  M. Geusz,et al.  Imaging gene expression in live transgenic mice after providing luciferin in drinking water , 2006, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[29]  David Piwnica-Worms,et al.  Real-time imaging of ligand-induced IKK activation in intact cells and in living mice , 2005, Nature Methods.

[30]  C. Contag,et al.  Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. , 2005, Journal of biomedical optics.

[31]  R. Müller,et al.  Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. , 2004, International journal of pharmaceutics.

[32]  V. Venkateswarlu,et al.  Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[33]  C. Contag,et al.  It's not just about anatomy: In vivo bioluminescence imaging as an eyepiece into biology , 2002, Journal of magnetic resonance imaging : JMRI.

[34]  R. Müller,et al.  Nanostructured lipid matrices for improved microencapsulation of drugs. , 2002, International journal of pharmaceutics.

[35]  S. Gambhir,et al.  Optical imaging of Renilla luciferase reporter gene expression in living mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[36]  David K. Stevenson,et al.  Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression , 2001, Transgenic Research.

[37]  Gregory R. Siragusa,et al.  Real-Time Monitoring of Escherichia coliO157:H7 Adherence to Beef Carcass Surface Tissues with a Bioluminescent Reporter , 1999, Applied and Environmental Microbiology.

[38]  Schwarz,et al.  Freeze-drying of drug-free and drug-loaded solid lipid nanoparticles (SLN). , 1997, International journal of pharmaceutics.

[39]  K. Nealson,et al.  Cloning, organization, and expression of the bioluminescence genes of Xenorhabdus luminescens , 1990, Journal of bacteriology.

[40]  R Fisher,et al.  Design of Experiments , 1936 .

[41]  Xiaoyuan Chen,et al.  Has Molecular and Cellular Imaging Enhanced Drug Discovery and Drug Development? , 2008, Drugs in R&D.

[42]  Casey Weaver,et al.  Noninvasive bioluminescence imaging in small animals. , 2008, ILAR journal.

[43]  T. Blackwell,et al.  Bioluminescence imaging. , 2005, Proceedings of the American Thoracic Society.

[44]  D. Piwnica-Worms,et al.  Spying on cancer: molecular imaging in vivo with genetically encoded reporters. , 2005, Cancer cell.