Neural circuitry mediating inflammation-induced central pain amplification in human experimental endotoxemia

[1]  S. Elsenbruch,et al.  Inflammation-induced pain sensitization in men and women: does sex matter in experimental endotoxemia? , 2015, Pain.

[2]  M. Lekander,et al.  Modality and sex differences in pain sensitivity during human endotoxemia , 2015, Brain, Behavior, and Immunity.

[3]  S. Elsenbruch,et al.  Inflammation-induced hyperalgesia: Effects of timing, dosage, and negative affect on somatic pain sensitivity in human experimental endotoxemia , 2014, Brain, Behavior, and Immunity.

[4]  M. Hutchinson.  Want more pain? Just add a dash of endotoxin to enhance your clinical pain model , 2014, Brain, Behavior, and Immunity.

[5]  L. Chang,et al.  Cytokine imbalance in irritable bowel syndrome: a systematic review and meta‐analysis , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[6]  O. Wolf,et al.  Experimental human endotoxemia enhances brain activity during social cognition. , 2014, Social cognitive and affective neuroscience.

[7]  M. Forsting,et al.  Placebo analgesia in patients with functional and organic abdominal pain: a fMRI study in IBS, UC and healthy volunteers , 2014, Gut.

[8]  J. Houtveen,et al.  Biological and psychological predictors of visceral pain sensitivity in healthy premenopausal women , 2014, European journal of pain.

[9]  S. Maier,et al.  Pathological pain and the neuroimmune interface , 2014, Nature Reviews Immunology.

[10]  M. Forsting,et al.  Towards understanding sex differences in visceral pain: Enhanced reactivation of classically-conditioned fear in healthy women , 2014, Neurobiology of Learning and Memory.

[11]  D. Borsook,et al.  Psychological processing in chronic pain: A neural systems approach , 2014, Neuroscience & Biobehavioral Reviews.

[12]  H. Engler,et al.  Endotoxin-induced experimental systemic inflammation in humans: A model to disentangle immune-to-brain communication , 2014, Brain, Behavior, and Immunity.

[13]  C. S. Hubbard,et al.  Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel syndrome. , 2013, Gastroenterology.

[14]  Noah D. Brenowitz,et al.  Integrated strategy for improving functional connectivity mapping using multiecho fMRI , 2013, Proceedings of the National Academy of Sciences.

[15]  M. Hutchinson,et al.  Low-dose endotoxin potentiates capsaicin-induced pain in man: Evidence for a pain neuroimmune connection , 2013, Brain, Behavior, and Immunity.

[16]  J. Scholz,et al.  White matter integrity of the descending pain modulatory system is associated with interindividual differences in placebo analgesia , 2012, PAIN®.

[17]  A. Masclee,et al.  Revisiting concepts of visceral nociception in irritable bowel syndrome , 2012, European journal of pain.

[18]  S. Elsenbruch,et al.  Experimental endotoxemia as a model to study neuroimmune mechanisms in human visceral pain , 2012, Annals of the New York Academy of Sciences.

[19]  J. Andrews,et al.  Sensory neuro-immune interactions differ between Irritable Bowel Syndrome subtypes , 2012, Gut.

[20]  Wen-Ming Luh,et al.  Differentiating BOLD and non-BOLD signals in fMRI time series using multi-echo EPI , 2012, NeuroImage.

[21]  S. Elsenbruch,et al.  Acute experimental endotoxemia induces visceral hypersensitivity and altered pain evaluation in healthy humans , 2012, PAIN®.

[22]  L. Watkins,et al.  Toll-like receptors in chronic pain , 2012, Experimental Neurology.

[23]  J. Groeger,et al.  Gut memories: Towards a cognitive neurobiology of irritable bowel syndrome , 2012, Neuroscience & Biobehavioral Reviews.

[24]  O. Wolf,et al.  Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans , 2011, PloS one.

[25]  J. Mogil,et al.  Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice , 2011, The Journal of Neuroscience.

[26]  C. Wilder-Smith.  The balancing act: endogenous modulation of pain in functional gastrointestinal disorders , 2011, Gut.

[27]  Sigrid Elsenbruch,et al.  Abdominal pain in Irritable Bowel Syndrome: A review of putative psychological, neural and neuro-immune mechanisms , 2011, Brain, Behavior, and Immunity.

[28]  J. Labus,et al.  Advances in imaging the brain-gut axis: functional gastrointestinal disorders. , 2011, Gastroenterology.

[29]  E. Mayer,et al.  The brain-gut axis in abdominal pain syndromes. , 2011, Annual review of medicine.

[30]  Kirsten Tillisch,et al.  Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. , 2011, Gastroenterology.

[31]  O. Wolf,et al.  Lipopolysaccharide-induced experimental immune activation does not impair memory functions in humans , 2010, Neurobiology of Learning and Memory.

[32]  M. Forsting,et al.  Patients with irritable bowel syndrome have altered emotional modulation of neural responses to visceral stimuli. , 2010, Gastroenterology.

[33]  P. Scully,et al.  Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity , 2010, The American Journal of Gastroenterology.

[34]  U. Baumgärtner,et al.  Multiple somatotopic representations of heat and mechanical pain in the operculo-insular cortex: a high-resolution fMRI study. , 2010, Journal of neurophysiology.

[35]  L. Öhman,et al.  Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions , 2010, Nature Reviews Gastroenterology &Hepatology.

[36]  M Forsting,et al.  Affective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: an fMRI study , 2009, Gut.

[37]  Benedikt A. Poser,et al.  Investigating the benefits of multi-echo EPI for fMRI at 7 T , 2009, NeuroImage.

[38]  Henry C. Lin,et al.  Immune activation and gut microbes in irritable bowel syndrome. , 2009, Gut and liver.

[39]  Irene Tracey,et al.  Imaging CNS modulation of pain in humans. , 2008, Physiology.

[40]  T. Dinan,et al.  Enhanced Cholinergic-Mediated Increase in the Pro-Inflammatory Cytokine IL-6 in Irritable Bowel Syndrome: Role of Muscarinic Receptors , 2008, The American Journal of Gastroenterology.

[41]  A. S. Andreasen,et al.  Human endotoxemia as a model of systemic inflammation. , 2008, Current medicinal chemistry.

[42]  J. Bueller,et al.  Reduced Brainstem Inhibition during Anticipated Pelvic Visceral Pain Correlates with Enhanced Brain Response to the Visceral Stimulus in Women with Irritable Bowel Syndrome , 2008, The Journal of Neuroscience.

[43]  P. McDonald,et al.  Brain, Behavior and Immunity in Cancer , 2008 .

[44]  M. Osterman.  Immune Activation in Patients With Irritable Bowel Syndrome , 2008 .

[45]  Irene Tracey,et al.  The Cerebral Signature for Pain Perception and Its Modulation , 2007, Neuron.

[46]  J. Brooks,et al.  Attentional modulation of visceral and somatic pain , 2007, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[47]  Thomas Bauermann,et al.  Cerebral activation in patients with somatoform pain disorder exposed to pain and stress: An fMRI study , 2007, NeuroImage.

[48]  W. Guo,et al.  Glial–Cytokine–Neuronal Interactions Underlying the Mechanisms of Persistent Pain , 2007, The Journal of Neuroscience.

[49]  F. Birklein,et al.  Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference values , 2006, PAIN.

[50]  Simon B. Eickhoff,et al.  Segregation of visceral and somatosensory afferents: An fMRI and cytoarchitectonic mapping study , 2006, NeuroImage.

[51]  D. Norris,et al.  BOLD contrast sensitivity enhancement and artifact reduction with multiecho EPI: Parallel‐acquired inhomogeneity‐desensitized fMRI , 2006, Magnetic resonance in medicine.

[52]  P. Scully,et al.  Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? , 2006, Gastroenterology.

[53]  I. Tracey,et al.  Cortical processing of visceral and somatic stimulation: Differentiating pain intensity from unpleasantness , 2005, Neuroscience.

[54]  Qasim Aziz,et al.  A Comparison of Visceral and Somatic Pain Processing in the Human Brainstem Using Functional Magnetic Resonance Imaging , 2005, The Journal of Neuroscience.

[55]  S. Maier,et al.  Immune regulation of central nervous system functions: from sickness responses to pathological pain , 2005, Journal of internal medicine.

[56]  David Thompson,et al.  Functional bowel disorders , 2005, Digestive Diseases and Sciences.

[57]  Walter Magerl,et al.  Neurogenic hyperalgesia versus painful hypoalgesia: two distinct mechanisms of neuropathic pain , 2002, Pain.

[58]  Markus Heinrichs,et al.  Der Mehrdimensionale Befindlichkeitsfragebogen (MDBF) , 2002 .

[59]  L. Buéno,et al.  Systemic lipopolysaccharide influences rectal sensitivity in rats: role of mast cells, cytokines, and vagus nerve. , 2000, American journal of physiology. Gastrointestinal and liver physiology.

[60]  L. Buéno,et al.  Brain interleukin-1β and tumor necrosis factor-α are involved in lipopolysaccharide-induced delayed rectal allodynia in awake rats , 2000, Brain Research Bulletin.

[61]  I. Tracey,et al.  Cortical Processing of Human Somatic and Visceral Sensation , 1999, The Journal of Neuroscience.

[62]  Steven F. Maier,et al.  Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states , 1995, Pain.