Structural analysis of spherical water-soluble dendrimer by SANS

Abstract Small-angle neutron scattering (SANS) data for aqueous solutions of the fifth-generation poly(amido amine) dendrimer with hydroxyl end groups have been analyzed on the basis of the dendrimer geometry and the SANS theory. The calculation using a five-layer model with water penetration was the best fit with the observed one. At the exterior region in the dendrimer, the segment chains were extended, and the segment density was smaller. Therefore, the solvent-filled void was larger there.