Creutzfeldt‐Jakob disease: A case of 16 years' duration

A 46‐year‐old man with Creutzfeldt‐Jakob disease confirmed postmortem had a 16‐year course of very slowly progressing incoordination and mental deterioration, suggesting Alzheimer's disease. The disease course transformed abruptly into a 7‐week terminal phase of florid Creutzfeldt‐Jakob disease. Dementing illnesses of unknown cause were present in the patient's paternal lineage.

[1]  C. Masters,et al.  Syndromes of amyotrophic lateral sclerosis and dementia: Relation to transmissible Creutzfeldt‐Jakob disease , 1983, Annals of neurology.

[2]  P. Daniel,et al.  The pathogenesis of transmissible spongiform encephalopathy: an ultrastructural study. , 1982, Brain : a journal of neurology.

[3]  A. Salazar,et al.  Alzheimer's Disease and Transmissible Virus Dementia (Creutzfeldt‐Jakob Disease) , 1982, Annals of the New York Academy of Sciences.

[4]  C. Masters,et al.  The familial occurrence of Creutzfeldt-Jakob disease and Alzheimer's disease. , 1981, Brain : a journal of neurology.

[5]  J. Chatelain,et al.  Familial Creutzfeldt-Jakob disease Autosomal dominance in 14 members over 3 generations , 1980, Journal of the Neurological Sciences.

[6]  P. Brown,et al.  Creutzfeldt‐Jakob disease in France: II. Clinical characteristics of 124 consecutive verified cases during the decade 1968–1977 , 1979, Annals of neurology.

[7]  H. V. Crevel,et al.  Familial Creutzfeldt-Jakob disease , 1979, Journal of the Neurological Sciences.

[8]  C. Masters,et al.  Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change. , 1978, Brain : a journal of neurology.

[9]  W. J. Brown,et al.  Familial neurological disease associated with spongiform encephalopathy. , 1976, Archives of neurology.

[10]  P. Daniel,et al.  Creutzfeldt-Jakob Disease , 1969 .

[11]  W. May.  CREUTZFELDT‐JAKOB DISEASE; 1. Survey of The Literature and Clinical Diagnosis , 1968 .