Association between depression and concurrent Type 2 diabetes outcomes varies by diabetes regimen

Aims  Although depression has weak associations with several Type 2 diabetes mellitus (DM) outcomes, it is possible that these associations are concentrated within certain patient subgroups that are more vulnerable to their effects. This study tested the hypothesis that depression is related to glycaemic control and diabetes‐related quality of life (DQOL) in patients who are prescribed injected insulin, but not those on oral glucose‐lowering agents alone.

[1]  D. Ronis,et al.  BRIEF REPORT: The burden of diabetes therapy , 2005, Journal of General Internal Medicine.

[2]  Irl B Hirsch,et al.  The relationship of depressive symptoms to symptom reporting, self-care and glucose control in diabetes. , 2003, General hospital psychiatry.

[3]  D. Nease,et al.  Adherence to Maintenance-Phase Antidepressant Medication as a Function of Patient Beliefs About Medication , 2005, The Annals of Family Medicine.

[4]  M. Amonkar,et al.  Depression in Patients with Type 2 Diabetes: Impact on Adherence to Oral Hypoglycemic Agents , 2006, The Annals of pharmacotherapy.

[5]  B. Anderson,et al.  Responsiveness of the Problem Areas In Diabetes (PAID) questionnaire , 2003, Diabetic medicine : a journal of the British Diabetic Association.

[6]  R. Rubin,et al.  Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. , 2005, Diabetes care.

[7]  R. B. Singer,et al.  Mortality in co-morbidity (II)--excess death rates derived from a follow-up study on 10,025 subjects divided into 4 groups with or without depression and diabetes mellitus. , 2007, Journal of insurance medicine.

[8]  D. Ronis,et al.  Brief report: the burden of diabetes therapy: implications for the design of effective patient-centered treatment regimens. , 2005, Journal of general internal medicine.

[9]  L. Green,et al.  Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence , 1986, Medical care.

[10]  R. Clouse,et al.  Depression in diabetic patients: the relationship between mood and glycemic control. , 2005, Journal of diabetes and its complications.

[11]  R. Glasgow,et al.  The summary of diabetes self-care activities measure: results from 7 studies and a revised scale. , 2000, Diabetes care.

[12]  S. Vale Clinical Depression Versus Distress Among Patients With Type 2 Diabetes: Not Just a Question of Semantics , 2007, Diabetes Care.

[13]  R. Carney,et al.  Depression and poor glycemic control: a meta-analytic review of the literature. , 2000, Diabetes care.

[14]  R. Spitzer,et al.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. , 1999, JAMA.

[15]  J. Cole,et al.  Daily stress variability, learned resourcefulness, regimen adherence, and metabolic control in type I diabetes mellitus: evaluation of a path model. , 1992, Journal of consulting and clinical psychology.

[16]  P. Pietschmann,et al.  Hormonal and blood glucose responsiveness as an indicator of specific emotional arousal in type 1 diabetics. , 1993, Journal of psychosomatic research.

[17]  K. Freedland,et al.  The prevalence of comorbid depression in adults with diabetes: a meta-analysis. , 2001, Diabetes care.

[18]  W. Polonsky,et al.  Psychological insulin resistance in patients with type 2 diabetes: the scope of the problem. , 2005, Diabetes care.

[19]  S. Norris,et al.  Depressive symptoms and mortality among persons with and without diabetes. , 2005, American journal of epidemiology.

[20]  J. Aikens,et al.  The mediating role of health beliefs in the relationship between depressive symptoms and medication adherence in persons with diabetes. , 2005, Research in social & administrative pharmacy : RSAP.

[21]  B. Bailey Mediators of Depression in Adults with Diabetes , 1996, Clinical nursing research.

[22]  R. E. Warren The stepwise approach to the management of type 2 diabetes. , 2004, Diabetes research and clinical practice.

[23]  S. Erickson,et al.  The Concordance of Self-Report With Other Measures of Medication Adherence: A Summary of the Literature , 2004, Medical care.

[24]  M. Feinglos,et al.  Depressed Mood Is a Factor in Glycemic Control in Type 1 Diabetes , 2001, Psychosomatic medicine.

[25]  J. Aikens,et al.  Patient-reported perceptions of side effects of antihyperglycemic medication and adherence to medication regimens in persons with diabetes mellitus. , 2007, Clinical therapeutics.

[26]  J. Aikens,et al.  Help-seeking for insomnia among adult patients in primary care. , 2005, The Journal of the American Board of Family Practice.

[27]  P. Parekh,et al.  Treatment regimen determines the relationship between depression and glycemic control. , 2005, Diabetes research and clinical practice.