Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology

[1]  J. Verhaagen,et al.  Recent advances in the therapeutic uses of chondroitinase ABC , 2019, Experimental Neurology.

[2]  H. Okano,et al.  Cell therapy for spinal cord injury using induced pluripotent stem cells , 2019, Regenerative therapy.

[3]  M. Fehlings,et al.  Regeneration of Spinal Cord Connectivity Through Stem Cell Transplantation and Biomaterial Scaffolds , 2019, Front. Cell. Neurosci..

[4]  M. Fehlings,et al.  Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury , 2018, Stem cell reports.

[5]  T. Dick,et al.  Rapid and robust restoration of breathing long after spinal cord injury , 2018, Nature Communications.

[6]  A. Burns,et al.  Transplanted enteric neural stem cells integrate within the developing chick spinal cord: implications for spinal cord repair , 2018, Journal of anatomy.

[7]  G. Barreto,et al.  Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs) , 2018, Glia.

[8]  A. Didangelos,et al.  Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury , 2018, Brain : a journal of neurology.

[9]  K. Anderson,et al.  Emerging Safety of Intramedullary Transplantation of Human Neural Stem Cells in Chronic Cervical and Thoracic Spinal Cord Injury , 2018, Neurosurgery.

[10]  T. Yi,et al.  Transplantation of human bone marrow‐derived clonal mesenchymal stem cells reduces fibrotic scar formation in a rat spinal cord injury model , 2018, Journal of tissue engineering and regenerative medicine.

[11]  J. Uney,et al.  Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury , 2017, PloS one.

[12]  K. Anderson,et al.  Safety of Autologous Human Schwann Cell Transplantation in Subacute Thoracic Spinal Cord Injury. , 2017, Journal of neurotrauma.

[13]  Charles Tator,et al.  Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury , 2017, Biomedical materials.

[14]  H. Ohta,et al.  Fertile offspring from sterile sex chromosome trisomic mice , 2017, Science.

[15]  M. Fehlings,et al.  Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury , 2017, PloS one.

[16]  M. Sofroniew,et al.  Cell biology of spinal cord injury and repair. , 2017, The Journal of clinical investigation.

[17]  D. Natarajan,et al.  Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon , 2017, Nature Communications.

[18]  Xiao Fan,et al.  Stem cell transplantation for spinal cord injury: a meta-analysis of treatment effectiveness and safety , 2017, Neural regeneration research.

[19]  M. Yousefifard,et al.  The combined application of human adipose derived stem cells and Chondroitinase ABC in treatment of a spinal cord injury model , 2017, Neuropeptides.

[20]  A. Goldstein,et al.  Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments , 2017, Pediatric Research.

[21]  P. Tam,et al.  White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies. , 2016, Developmental biology.

[22]  Yoshihide Hayashizaki,et al.  Genomic Instability of iPSCs: Challenges Towards Their Clinical Applications , 2016, Stem Cell Reviews and Reports.

[23]  A. Burns,et al.  In vivo transplantation of fetal human gut‐derived enteric neural crest cells , 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[24]  Mathieu von Joest,et al.  Genomic stability during cellular reprogramming: Mission impossible? , 2016, Mutation research.

[25]  Jeremy S. Biane,et al.  Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration , 2016, Nature Medicine.

[26]  W. Boesmans,et al.  In Vivo Transplantation of Enteric Neural Crest Cells into Mouse Gut; Engraftment, Functional Integration and Long-Term Safety , 2016, PloS one.

[27]  J. Dietrich,et al.  Engraftment of enteric neural progenitor cells into the injured adult brain , 2016, BMC Neuroscience.

[28]  S. Sakiyama-Elbert,et al.  Combination therapy of stem cell derived neural progenitors and drug delivery of anti-inhibitory molecules for spinal cord injury. , 2015, Acta biomaterialia.

[29]  M. Hayashibe,et al.  Locomotor improvement of spinal cord-injured rats through treadmill training by forced plantar placement of hind paws , 2015, Spinal Cord.

[30]  Shuxin Li,et al.  Molecular mechanisms of scar-sourced axon growth inhibitors , 2015, Brain Research.

[31]  J. Verhaagen,et al.  Chondroitinase gene therapy improves upper limb function following cervical contusion injury , 2015, Experimental Neurology.

[32]  Zhen-Hua Qu,et al.  Propofol promotes spinal cord injury repair by bone marrow mesenchymal stem cell transplantation , 2015, Neural regeneration research.

[33]  A. Didangelos,et al.  Regulation of IL-10 by Chondroitinase ABC Promotes a Distinct Immune Response following Spinal Cord Injury , 2014, The Journal of Neuroscience.

[34]  Changlian Zhu,et al.  Transplantation of Enteric Neural Stem/Progenitor Cells into the Irradiated Young Mouse Hippocampus , 2014, Cell transplantation.

[35]  G. Raisman,et al.  Functional Regeneration of Supraspinal Connections in a Patient with Transected Spinal Cord following Transplantation of Bulbar Olfactory Ensheathing Cells with Peripheral Nerve Bridging , 2014, Cell transplantation.

[36]  O. Steward,et al.  Characterization of Ectopic Colonies That Form in Widespread Areas of the Nervous System with Neural Stem Cell Transplants into the Site of a Severe Spinal Cord Injury , 2014, The Journal of Neuroscience.

[37]  A. Burns,et al.  Lentiviral labeling of mouse and human enteric nervous system stem cells for regenerative medicine studies , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[38]  A. Fallah,et al.  Iranian Journal of Basic Medical Sciences Comparison of Human Adipose-derived Stem Cells and Chondroitinase Abc Transplantation on Locomotor Recovery in the Contusion Model of Spinal Cord Injury in Rats , 2022 .

[39]  J. Silver,et al.  Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer , 2014, Current Opinion in Neurobiology.

[40]  A. Burns,et al.  Neural stem cell therapies for enteric nervous system disorders , 2014, Nature Reviews Gastroenterology &Hepatology.

[41]  D. Dinh,et al.  Mesenchymal stem cells in the treatment of spinal cord injuries: A review. , 2014, World journal of stem cells.

[42]  Rafael J. Yáñez-Muñoz,et al.  Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury , 2014, The Journal of Neuroscience.

[43]  F. Biering-Sørensen,et al.  Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: Systematic review with meta-analyses of rat models , 2014, Neurobiology of Disease.

[44]  E. Bradbury,et al.  Review: Manipulating the extracellular matrix and its role in brain and spinal cord plasticity and repair , 2014, Neuropathology and applied neurobiology.

[45]  S. Poser,et al.  Growing neural stem cells from conventional and nonconventional regions of the adult rodent brain. , 2013, Journal of visualized experiments : JoVE.

[46]  R. Xu,et al.  Transplantation of autologous bone marrow mesenchymal stem cells in the treatment of complete and chronic cervical spinal cord injury , 2013, Brain Research.

[47]  A. Harvey,et al.  Tissue sparing, behavioral recovery, supraspinal axonal sparing/regeneration following sub-acute glial transplantation in a model of spinal cord contusion , 2013, BMC Neuroscience.

[48]  G. Raisman,et al.  Transplantation of Autologous Olfactory Ensheathing Cells in Complete Human Spinal Cord Injury , 2013, Cell transplantation.

[49]  Yang Liu,et al.  A self-assembling peptide reduces glial scarring, attenuates post-traumatic inflammation and promotes neurological recovery following spinal cord injury. , 2013, Acta biomaterialia.

[50]  Yoji Sato,et al.  Tumorigenicity studies for human pluripotent stem cell-derived products. , 2013, Biological & pharmaceutical bulletin.

[51]  H. Okano,et al.  Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells , 2012, Cell Research.

[52]  M. Tuszynski,et al.  Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury , 2012, Cell.

[53]  R. Lahesmaa,et al.  Genetic and epigenetic stability of human pluripotent stem cells , 2012, Nature Reviews Genetics.

[54]  N. Boulis,et al.  Stem cell therapy for the spinal cord , 2012, Stem Cell Research & Therapy.

[55]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[56]  K. Ha,et al.  Fate of Transplanted Bone Marrow Derived Mesenchymal Stem Cells Following Spinal Cord Injury in Rats by Transplantation Routes , 2012, Journal of Korean medical science.

[57]  I. Sung,et al.  Long-term results of spinal cord injury therapy using mesenchymal stem cells derived from bone marrow in humans. , 2012, Neurosurgery.

[58]  Xiaohong Kong,et al.  Transplantation of Autologous Activated Schwann Cells in the Treatment of Spinal Cord Injury: Six Cases, more than Five Years of Follow-up , 2012, Cell transplantation.

[59]  S. McMahon,et al.  Conduction Failure following Spinal Cord Injury: Functional and Anatomical Changes from Acute to Chronic Stages , 2011, The Journal of Neuroscience.

[60]  Rafael J. Yáñez-Muñoz,et al.  Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons , 2011, Journal of Neuroscience Methods.

[61]  S. David,et al.  Repertoire of microglial and macrophage responses after spinal cord injury , 2011, Nature Reviews Neuroscience.

[62]  E. Bradbury,et al.  Manipulating the glial scar: Chondroitinase ABC as a therapy for spinal cord injury , 2011, Brain Research Bulletin.

[63]  M. Fehlings,et al.  Synergistic Effects of Transplanted Adult Neural Stem/Progenitor Cells, Chondroitinase, and Growth Factors Promote Functional Repair and Plasticity of the Chronically Injured Spinal Cord , 2010, The Journal of Neuroscience.

[64]  J. Fawcett,et al.  Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells , 2010, Journal of biotechnology.

[65]  J. Houlé,et al.  Administration of chondroitinase ABC rostral or caudal to a spinal cord injury site promotes anatomical but not functional plasticity. , 2009, Journal of neurotrauma.

[66]  A. Stenzl,et al.  Expansion and differentiation of neural progenitors derived from the human adult enteric nervous system. , 2009, Gastroenterology.

[67]  A. Burns,et al.  Enteric nervous system stem cells derived from human gut mucosa for the treatment of aganglionic gut disorders. , 2009, Gastroenterology.

[68]  M. Cheong,et al.  Transplantation of Embryonic Fibroblasts Treated with Platelet-Rich Plasma Induces Osteogenesis in SAMP8 Mice Monitored by Molecular Imaging , 2009, Journal of Nuclear Medicine.

[69]  Charles Tator,et al.  Adult Spinal Cord Stem/Progenitor Cells Transplanted as Neurospheres Preferentially Differentiate into Oligodendrocytes in the Adult Rat Spinal Cord , 2008, Cell transplantation.

[70]  L. Turner-Stokes,et al.  Chronic spinal cord injury: management of patients in acute hospital settings. , 2008, Clinical medicine.

[71]  Michael Unser,et al.  User‐friendly semiautomated assembly of accurate image mosaics in microscopy , 2007, Microscopy research and technique.

[72]  M. Murray,et al.  Transplantation of Neuronal and Glial Restricted Precursors into Contused Spinal Cord Improves Bladder and Motor Functions, Decreases Thermal Hypersensitivity, and Modifies Intraspinal Circuitry , 2005, The Journal of Neuroscience.

[73]  I. Fischer,et al.  Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord , 2005, Experimental Neurology.

[74]  M. Tuszynski,et al.  Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury , 2003, Experimental Neurology.

[75]  H. Okano,et al.  Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats , 2002, Journal of neuroscience research.

[76]  James W. Fawcett,et al.  Chondroitinase ABC promotes functional recovery after spinal cord injury , 2002, Nature.

[77]  J. Mcdonald,et al.  Spinal-cord injury , 2002, The Lancet.

[78]  J. Fawcett,et al.  Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC , 2001, Nature Neuroscience.

[79]  C. Greer,et al.  Olfactory Ensheathing Cells: Bridging the Gap in Spinal Cord Injury , 2000, Neurosurgery.

[80]  L. Noble,et al.  Vascular events after spinal cord injury: contribution to secondary pathogenesis. , 2000, Physical therapy.

[81]  J. Silver,et al.  Injury-Induced Proteoglycans Inhibit the Potential for Laminin-Mediated Axon Growth on Astrocytic Scars , 1995, Experimental Neurology.

[82]  R. U. Margolis,et al.  Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules , 1993, The Journal of cell biology.

[83]  R. Borgens,et al.  Grafting in acute spinal cord injury: Morphological and immunological aspects of transplanted adult rat enteric ganglia , 1993, Neuroscience.

[84]  A. Björklund,et al.  Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord. , 1992, Neuroreport.

[85]  J. Silver,et al.  Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[86]  H J Gundersen,et al.  The efficiency of systematic sampling in stereology and its prediction * , 1987, Journal of microscopy.

[87]  H. M. Geller,et al.  An in vitro model of reactive astrogliosis and its effect on neuronal growth. , 2012, Methods in molecular biology.

[88]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[89]  J. Fawcett,et al.  Chondroitin sulphate proteoglycans in the CNS injury response. , 2002, Progress in brain research.

[90]  J. Fawcett,et al.  Chondroitin sulphate proteoglycans: inhibitory components of the glial scar. , 2001, Progress in brain research.