GIANT CELL REPARATIVE GRANULOMA ASSOCIATED WITH MANDIBULAR FRACTURE IN AN ELDERLY EDENTULOUS PATIENT : CASE

Giant cell reparative granuloma (GCRG) is a benign reactive intraosseous tumour in the head and neck region, characterized by the presence of multi-nucleated giant cells. It often arises in the first 3 decades of life, with a peak in the second and third decades. However initial presentation of GCRG in elderly patients is rare. The majority of patients are asymptomatic and, in some patients, the lesions are incidentally discovered during radiologic examinations. Presentation with pathologic fractures is rare. The treatment of GCRG is usually surgical, but treatment procedures vary depending on the case. The case reported here describes an elderly edentulous female with a pathologic fracture in the anterior mandibular region. Attention has been focused on the dental findings by computed tomography and surgical treatment of GCRG.

[1]  Somit Mittal,et al.  Multifocal giant cell reparative granuloma involving maxilla and mandible: a rare entity , 2015, Annals of Saudi medicine.

[2]  A. Demirbaş,et al.  The Peripheral Giant Cell Granuloma in Edentulous Patients: Report of Three Unique Cases , 2010, European journal of dentistry.

[3]  B. Erdoğan,et al.  Idiopathic bilateral central giant cell reparative granuloma of jaws: a case report and literature review. , 2010, International journal of pediatric otorhinolaryngology.

[4]  G. Paludetti,et al.  Advanced giant cell reparative granuloma of the mandible: radiological features and surgical treatment. , 2006, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[5]  M. Giansanti,et al.  Giant cell granuloma of the maxilla: case report. , 2004, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[6]  M. A. Rawashdeh,et al.  The surgical treatment of central giant cell granuloma of the mandible. , 2002, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[7]  J. Medina,et al.  Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids , 2000, Head & neck.

[8]  M. Harris Central giant cell granulomas of the jaws regress with calcitonin therapy. , 1993, The British journal of oral & maxillofacial surgery.

[9]  E. Masson,et al.  Parathyroid carcinoma presenting with a brown tumour of the mandible in a young man. , 1993, The British journal of oral & maxillofacial surgery.

[10]  C. Waldron,et al.  Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study. , 1993, Oral surgery, oral medicine, and oral pathology.

[11]  A. Marrogi,et al.  Multifocal central giant cell lesions of the maxillofacial skeleton: a case report. , 1990, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[12]  A. Greenberg,et al.  Bilateral giant cell granulomata of the mandible: report of case. , 1988, Journal of the American Dental Association.

[13]  L. Eisenbud,et al.  Central giant cell granuloma of the jaws: experiences in the management of thirty-seven cases. , 1988, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[14]  L. Kaban,et al.  Central giant cell lesions of the mandible and maxilla: a clinicopathologic and cytometric study. , 1987, Oral surgery, oral medicine, and oral pathology.

[15]  H. Jaffe Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-oseous) dysplasia of the jawbones. , 1953, Oral surgery, oral medicine, and oral pathology.