Transorale Therapiestrategien bei Kopf-Hals-Tumoren

The introduction of transoral endoscopic surgery resulted in a significant reduction of surgical trauma and a paradigm change from transcervical to transoral surgical treatment in head and neck tumors. In selected cases minimally invasive transoral resections allow a reduction of morbidity without deteriorating oncological results. Thus, transoral surgical techniques gained more acceptance, led to an extension of the indications and technologies as well as an improvement of surgical instruments.Depending on the anatomical localization transoral treatment strategies and their indications are described and relevant literature is discussed according to new developments and results.

[1]  Glanz Pathomorphologische Aspekte zur transoralen Resektion von Hypopharynxkarzinomen mit Erhalt des Kehlkopfes1 , 1999 .

[2]  A. J. Maniglia Indications and techniques of midfacial degloving. A 15-year experience. , 1986, Archives of otolaryngology--head & neck surgery.

[3]  G. Allen,et al.  The sublabial approach for extensive nasal and sinus resection , 1981, The Laryngoscope.

[4]  A. J. Maniglia,et al.  Midfacial degloving for the management of nasal, sinus, and skull-base neoplasms. , 1995, Otolaryngologic clinics of North America.

[5]  E. Rosenthal,et al.  Robotic-assisted surgery for primary or recurrent oropharyngeal carcinoma. , 2010, Archives of otolaryngology--head & neck surgery.

[6]  P. Goudet,et al.  Thyroïdectomie endoscopique par une approche médiane avec insufflation gazeuse : analyse des 100 premiers patients , 2007 .

[7]  R. K. Davis,et al.  Treatment of hypopharyngeal carcinoma: A 10‐year review of 1, 362 cases , 1987, The Laryngoscope.

[8]  D. Brasnu,et al.  Organ preservation surgery for laryngeal squamous cell carcinoma: Low incidence of thyroid cartilage invasion , 2010, The Laryngoscope.

[9]  M. Kron,et al.  Transoral carbon dioxide laser microsurgery for recurrent glottic carcinoma after radiotherapy , 2004, Head & neck.

[10]  G. Tartaro,et al.  CO(2) laser surgery in the treatment of glottic cancer. , 2005, Head & neck.

[11]  S. Zeitels,et al.  Voice and Treatment Outcome from Phonosurgical Management of Early Glottic Cancer , 2002, The Annals of otology, rhinology & laryngology. Supplement.

[12]  H. Christiansen,et al.  Organ Preserving Transoral Laser Microsurgery for Cancer of the Hypopharynx , 2008, The Laryngoscope.

[13]  P. Bradley,et al.  Primary treatment of the anterior vocal commissure squamous carcinoma , 2006, European Archives of Oto-Rhino-Laryngology and Head & Neck.

[14]  G. Weinstein,et al.  Transoral robotic surgery: does the ends justify the means? , 2009, Current opinion in otolaryngology & head and neck surgery.

[15]  G. Weinstein,et al.  Selective neck dissection and deintensified postoperative radiation and chemotherapy for oropharyngeal cancer: A subset analysis of the university of pennsylvania transoral robotic surgery trial , 2010, The Laryngoscope.

[16]  J. Choe,et al.  Postauricular and Axillary Approach Endoscopic Neck Surgery: A New Technique , 2009, World Journal of Surgery.

[17]  P. Ambrosch The role of laser microsurgery in the treatment of laryngeal cancer , 2007, Current opinion in otolaryngology & head and neck surgery.

[18]  J. Werner,et al.  Transoral laser microsurgery in carcinomas of the oral cavity, pharynx, and larynx. , 2002, Cancer control : journal of the Moffitt Cancer Center.

[19]  J. Shah,et al.  Combined Surgery and Radiation Therapy for Squamous Cell Carcinoma of the Hypopharynx , 1997, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[20]  C. Piazza,et al.  Phonosurgery after endoscopic cordectomies , 2007, European Archives of Oto-Rhino-Laryngology.

[21]  R. Ferris,et al.  Elective Neck Dissection and Survival in Patients With Squamous Cell Carcinoma of the Oral Cavity and Oropharynx , 2004, The Laryngoscope.

[22]  R. Esclamado,et al.  Primary Radiation Therapy for Early Glottic Cancer , 2001, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[23]  M. Kron,et al.  Organ Preservation by Transoral Laser Microsurgery in Piriform Sinus Carcinoma , 2001, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[24]  H. Iro,et al.  T1 and T2 hypopharyngeal cancer treatment with laser microsurgery , 2010, Journal of surgical oncology.

[25]  H. Eckel,et al.  Surgical Treatment for Hypopharynx Carcinoma: Feasibility, Mortality, and Results , 2001, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[26]  H. Christiansen,et al.  Long-term follow-up after transoral laser microsurgery and adjuvant radiotherapy for advanced recurrent squamous cell carcinoma of the head and neck. , 2006, International journal of radiation oncology, biology, physics.

[27]  P. Bradley,et al.  Current trends in initial management of hypopharyngeal cancer: The declining use of open surgery , 2012, Head & neck.

[28]  S. Stoeckli,et al.  Outcome of patients after treatment for a squamous cell carcinoma of the oropharynx , 2009, The Laryngoscope.

[29]  M. Strong,et al.  Laser Surgery in the Larynx Early Clinical Experience with Continuous Co2 Laser , 1972, The Annals of otology, rhinology, and laryngology.

[30]  D. Noh,et al.  Endoscopic Thyroidectomy Using a New Bilateral Axillo-Breast Approach , 2007, World Journal of Surgery.

[31]  L. Wirth,et al.  Cetuximab and radiotherapy for head and neck cancer. , 2006, The New England journal of medicine.

[32]  A. Berghaus [Midfacial degloving]. , 1990, HNO.

[33]  W. Thorstad,et al.  Transoral laser microsurgery (TLM) ± adjuvant therapy for advanced stage oropharyngeal cancer , 2009, The Laryngoscope.

[34]  H. Tideman Multiple synchronous and metachronous cancers of the upper aerodigestive tract: A nine-year study , 1990 .

[35]  G. Snow,et al.  Parapharyngeal tumours: a review of 23 cases. , 1989, Clinical otolaryngology and allied sciences.

[36]  D. Brasnu,et al.  Evidence‐based review of treatment options for patients with glottic cancer , 2011, Head & neck.

[37]  T. Gupta,et al.  Squamous cell carcinoma of the hypopharynx: Single-institution outcome analysis of a large cohort of patients treated with primary non-surgical approaches , 2009, Acta oncologica.

[38]  S. Blaugrund,et al.  Degloving approach for total excision of inverted papilloma , 1984, The Laryngoscope.

[39]  H. Christiansen,et al.  Adjuvant radiotherapy after transoral laser microsurgery for advanced squamous carcinoma of the head and neck. , 2005, International journal of radiation oncology, biology, physics.

[40]  P. Ambrosch 6 Laser im oberen Aerodigestivtrakt bei bösartigen Erkrankungen , 2003 .

[41]  H. Honda,et al.  Chemoradiation therapy with or without salvage surgery for early squamous cell carcinoma of the hypopharynx. , 2005, International journal of radiation oncology, biology, physics.

[42]  Robert E. Hillman,et al.  Stroboscopic Assessment of Vocal Fold Keratosis and Glottic Cancer , 2001, The Annals of otology, rhinology, and laryngology.

[43]  C. Gourin,et al.  Primary surgery for oropharyngeal cancer , 2010, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[44]  B. Wollenberg,et al.  Chirurgie der parapharyngealen Adenome , 2007, HNO.

[45]  P. Nicolai,et al.  Transoral CO2 laser treatment for Tis–T3 glottic cancer: The University of Brescia experience on 595 patients , 2009, Head & neck.

[46]  H. Rudert,et al.  Erfahrungen mit dem CO2-Laser unter besonderer Berücksichtigung der Therapie von Stimmbandkarzinomen , 1983 .

[47]  C. Snyderman,et al.  Minimally invasive techniques for head and neck malignancies: current indications, outcomes and future directions , 2011, European Archives of Oto-Rhino-Laryngology.

[48]  G. Kleinrensink,et al.  Natural orifice surgery on thyroid gland: totally transoral video-assisted thyroidectomy (TOVAT): report of first experimental results of a new surgical method , 2009, Surgical Endoscopy.

[49]  G. Poissonnet,et al.  T1-T2 NO oropharyngeal cancers treated with surgery alone. A GETTEC study , 2004, European Archives of Oto-Rhino-Laryngology and Head & Neck.

[50]  J. R. Chandler,et al.  Transoral excision of lateral parapharyngeal space tumors presenting intraorally , 1988, The Laryngoscope.

[51]  Marc Remacle,et al.  Transoral robotic surgery for the management of head and neck tumors: learning curve , 2011, European Archives of Oto-Rhino-Laryngology.

[52]  W. Thumfart,et al.  Transoral laser resection with staged discontinuous neck dissection for oral cavity and oropharynx squamous cell carcinoma , 1995, The Laryngoscope.

[53]  J. H. Brandenburg,et al.  Clinical underestimation of laryngeal cancer. Predictive indicators. , 1993, Archives of otolaryngology--head & neck surgery.

[54]  W. Lawson,et al.  Tumors of the Parapharyngeal Space Preoperative Evaluation, Diagnosis and Surgical Approaches , 1981, The Annals of otology, rhinology & laryngology. Supplement.

[55]  G. Barbash,et al.  New technology and health care costs--the case of robot-assisted surgery. , 2010, The New England journal of medicine.

[56]  G. H. Yeung Endoscopic thyroid surgery today: a diversity of surgical strategies. , 2002, Thyroid : official journal of the American Thyroid Association.

[57]  D. Kennedy,et al.  The versatile midface degloving approach , 1988, The Laryngoscope.

[58]  E. Myers,et al.  Primary surgery as treatment for early squamous cell carcinoma of the tonsil , 2000, Head and Neck.

[59]  W. Steiner Experience in endoscopic laser surgery of malignant tumours of the upper aero-digestive tract. , 1988, Advances in oto-rhino-laryngology.

[60]  Jonathan R. Clark,et al.  Outcomes of primary surgical treatment of T1 and T2 carcinomas of the oropharynx , 2009, The Laryngoscope.

[61]  S. Stoeckli,et al.  Quality of life after different treatment modalities for carcinoma of the oropharynx , 2003, The Laryngoscope.

[62]  A. Dietz,et al.  Organerhalt bei Larynx-Hypopharynx-Karzinomen , 2007, Der Onkologe.

[63]  H. Iro,et al.  Evaluation of available surgical management options for early supraglottic cancer , 2009, Head & neck.

[64]  E. Genden,et al.  Transoral Robotic Surgery Using a Carbon Dioxide Flexible Laser for Tumors of the Upper Aerodigestive Tract , 2008, The Laryngoscope.

[65]  William C. Perry,et al.  Transoral laser microsurgery for recurrent laryngeal and pharyngeal cancer , 2008, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[66]  H. Iro,et al.  Ergebnisse der transoralen Laserresektion bei T1-2 Karzinomen von Oropharynx, Hypopharynx und Larynx , 2011, Laryngo-Rhino-Otologie.

[67]  G. Funk,et al.  The National Cancer Data Base report on cancer of the head and neck. , 1998, Archives of otolaryngology--head & neck surgery.

[68]  W. Steiner,et al.  Carbon Dioxide Laser Microsurgery for Early Supraglottic Carcinoma , 1998, The Annals of otology, rhinology, and laryngology.

[69]  E. Rosenthal,et al.  Functional Outcomes after Transoral Robotic Surgery for Head and Neck Cancer , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[70]  R. Rödel,et al.  Endoscopic laser surgery of early glottic cancer: Involvement of the anterior commissure , 2009, Head & neck.

[71]  G. Weinstein,et al.  Transoral robotic surgery and human papillomavirus status: Oncologic results , 2011, Head & neck.

[72]  M. Bernal-Sprekelsen,et al.  Transoral laser microsurgery for T3 laryngeal tumors: Prognostic factors , 2009, Head & neck.

[73]  P. O'dwyer,et al.  Endoscopic , 2021 .

[74]  B. O'Sullivan,et al.  The Natural History of Patients With Squamous Cell Carcinoma of the Hypopharynx , 2008, The Laryngoscope.

[75]  H. Schardey,et al.  Invisible Scar Endoscopic Dorsal Approach Thyroidectomy: A Clinical Feasibility Study , 2010, World Journal of Surgery.

[76]  T. Wilhelm,et al.  Ultrasound studies on the shift of cervical tissues in different head and neck positions--impact on transoral endoscopic, minimally invasive and conventional thyroid surgery. , 2011, Ultrasound in medicine & biology.

[77]  K. Ang,et al.  National Cancer Database report on cancer of the head and neck: 10‐Year update , 2009, Head & neck.

[78]  W. Thumfart,et al.  Transoral laser surgery for early glottic carcinoma , 2000, European Archives of Oto-Rhino-Laryngology.

[79]  H. Rudert,et al.  Transoral carbon-dioxide laser resection of hypopharyngeal carcinoma , 2003, European Archives of Oto-Rhino-Laryngology.

[80]  E. Rosenthal,et al.  Robot-assisted surgery for upper aerodigestive tract neoplasms. , 2009, Archives of otolaryngology--head & neck surgery.

[81]  J. Werner,et al.  Transoral Carbon Dioxide Laser Resection of Supraglottic Carcinoma , 1999, The Annals of otology, rhinology, and laryngology.

[82]  E. Abraham,et al.  Pleomorphic adenoma of minor salivary gland in the parapharyngeal space , 2003, World journal of surgical oncology.

[83]  G. Weinstein,et al.  Transoral Robotic Surgery: Supraglottic Partial Laryngectomy , 2007, The Annals of otology, rhinology, and laryngology.

[84]  W P WORK,et al.  TUMORS OF THE PARAPHARYNGEAL SPACE. , 1969, Transactions of the Pacific Coast Oto-Ophthalmological Society annual meeting.

[85]  M. Kron,et al.  Transoral laser microsurgery for squamous cell carcinoma of the base of the tongue. , 2003, Archives of otolaryngology--head & neck surgery.

[86]  L. Turek,et al.  Human Papillomavirus Type 16 (HPV-16) Genomes Integrated in Head and Neck Cancers and in HPV-16-Immortalized Human Keratinocyte Clones Express Chimeric Virus-Cell mRNAs Similar to Those Found in Cervical Cancers , 2010, Journal of Virology.

[87]  Giorgio Peretti,et al.  ‘Biologic endoscopy’: optimization of upper aerodigestive tract cancer evaluation , 2011, Current opinion in otolaryngology & head and neck surgery.

[88]  K. Olsen,et al.  Transoral resection of tonsillar squamous cell carcinoma , 2009, The Laryngoscope.

[89]  G. Litynski Endoscopic Surgery: The History, the Pioneers , 2014, World Journal of Surgery.

[90]  R. Hayden,et al.  Transoral laser microsurgery for advanced laryngeal cancer. , 2007, Archives of otolaryngology--head & neck surgery.

[91]  W. Han,et al.  Endoscopic Thyroidectomy for Thyroid Malignancies: Comparison with Conventional Open Thyroidectomy , 2007, World Journal of Surgery.

[92]  E. Genden,et al.  Transoral robotic resection and reconstruction for head and neck cancer , 2011, The Laryngoscope.

[93]  H. Stein,et al.  Transoral access for endoscopic thyroid resection , 2008, Surgical Endoscopy.

[94]  S. Preuß,et al.  Humane Papillomviren und Oropharynxkarzinome , 2009, HNO.

[95]  U. Vorwerk,et al.  Fortschritte der endoskopischen Diagnostik von Dysplasien und Karzinomen des Larynx , 2012, HNO.

[96]  K. Olsen,et al.  Transoral robotic surgery for oropharyngeal squamous cell carcinoma: A prospective study of feasibility and functional outcomes , 2009, The Laryngoscope.

[97]  J. Rodrigo,et al.  Efficacy of routine bilateral neck dissection in the management of the N0 neck in T1–T2 unilateral supraglottic cancer , 2006, Head & neck.

[98]  L. Delbridge,et al.  “Scarless” (in the Neck) Endoscopic Thyroidectomy (SET): An Evidence-based Review of Published Techniques , 2008, World Journal of Surgery.

[99]  G. Psychogios,et al.  Effect of repeated laser microsurgical operations on laryngeal cancer prognosis , 2009, Head & neck.

[100]  M. Varvares,et al.  Surgical margin determination in head and neck oncology: Current clinical practice. The results of an International American Head and Neck Society Member Survey , 2005, Head & neck.

[101]  R. Y. Lim,et al.  Transoral laser surgery for supraglottic cancer. , 1995, Clinical laser monthly.

[102]  K. Sesterhenn,et al.  Diagnostik und Zugangswege bei Tumoren des Parapharyngealraums - Eine Übersicht , 2002 .

[103]  M. Strome,et al.  Transoral Robot‐Assisted CO2 Laser Supraglottic Laryngectomy: Experimental and Clinical Data , 2007, The Laryngoscope.

[104]  Hans edmund Eckel Endoscopic Laser Resection of Supraglottic Carcinoma , 1997 .

[105]  W Steiner,et al.  Results of curative laser microsurgery of laryngeal carcinomas. , 1993, American journal of otolaryngology.

[106]  H. Eckel,et al.  Local Recurrences following Transoral Laser Surgery for Early Glottic Carcinoma: Frequency, Management, and Outcome , 2001, The Annals of otology, rhinology, and laryngology.

[107]  S. Stringer,et al.  Squamous cell carcinoma of the oropharynx , 2002, Cancer.

[108]  J. Stockman Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer , 2012 .

[109]  A. Sewnaik,et al.  Treatment of hypopharyngeal carcinoma: analysis of nationwide study in the Netherlands over a 10‐year period , 2005, Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery.

[110]  O. Kleinsasser Die Laryngomikroskopie (Lupenlaryngoskopie) und ihre Bedeutung für die Erkennung der Vorerkrankungen und Frühformen des Stimmlippencarcinoms , 1962, Archiv für Ohren-, Nasen- und Kehlkopfheilkunde.

[111]  T. Loree,et al.  Surgery versus radiation therapy as single‐modality treatment of tonsillar fossa carcinoma: The roswell park cancer institute experience (1971–1991) , 1998, The Laryngoscope.

[112]  R. Firsching,et al.  Tumoren und Pseudotumoren der frontalen Schädelbasis , 1993 .

[113]  J. Converse,et al.  The midface degloving procedure. , 1974, Plastic and reconstructive surgery.

[114]  C. Arens Open Partial Resection for Malignant Glottic Tumors , 2009 .

[115]  W. Thumfart,et al.  Juvenile Nasopharyngeal Angiofibroma: Management and Therapy , 2001, The Laryngoscope.

[116]  D. Heron,et al.  Role of Surgery in Limited (T1‐2, N0‐1) Cancers of the Oropharynx , 2008, The Laryngoscope.

[117]  G. Leschber,et al.  Development of a new trans-oral endoscopic approach for mediastinal surgery based on 'natural orifice surgery': preclinical studies on surgical technique, feasibility, and safety. , 2011, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[118]  V. Lund Surgical management of midfacial tumors: transfacial degloving, midfacial degloving, or endoscopic approach? , 2001 .

[119]  J. Beitler,et al.  Current trends in initial management of laryngeal cancer: the declining use of open surgery , 2009, European Archives of Oto-Rhino-Laryngology.

[120]  C. Gourin,et al.  A contemporary review of indications for primary surgical care of patients with squamous cell carcinoma of the head and neck , 2009, The Laryngoscope.

[121]  M. Csanády,et al.  Transoral CO2 laser management for selected supraglottic tumors and neck dissection , 2011, European Archives of Oto-Rhino-Laryngology.