Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention.

The proven benefits of antibiotic stewardship programs (ASPs) for optimizing antibiotic use and minimizing adverse events, such as Clostridium difficile and antibiotic resistance, have prompted the Centers for Disease Control and Prevention (CDC) to recommend that all hospitals have an ASP. This article summarizes Core Elements of Hospital Antibiotic Stewardship Programs, a recently released CDC document focused on defining the infrastructure and practices of coordinated multidisciplinary programs to improve antibiotic use and patient care in US hospitals.

[1]  Edward H. Lee American society of health-system pharmacists. , 2011, P & T : a peer-reviewed journal for formulary management.

[2]  S. Fridkin,et al.  Implementing a strategy for monitoring inpatient antimicrobial use among hospitals in the United States. , 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  C. Ohl,et al.  Antimicrobial stewardship programs in community hospitals: the evidence base and case studies. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[4]  C. Robertson,et al.  Approaching zero: temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum β-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus. , 2013, International journal of antimicrobial agents.

[5]  Jennifer L Czerwinski,et al.  Clinical and economic outcomes from a community hospital's antimicrobial stewardship program. , 2013, American journal of infection control.

[6]  Christoph U. Lehmann,et al.  Sustained Savings from a Longitudinal Cost Analysis of an Internet-Based Preapproval Antimicrobial Stewardship Program , 2013, Infection Control & Hospital Epidemiology.

[7]  R. Fagan,et al.  Vital Signs: Improving Antibiotic Use Among Hospitalized Patients , 2014, MMWR. Morbidity and mortality weekly report.

[8]  J. Burke,et al.  Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship , 2007 .

[9]  O. Dekkers,et al.  Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics. , 2012, The Journal of antimicrobial chemotherapy.

[10]  Jeffrey M. Rohde,et al.  Role of the hospitalist in antimicrobial stewardship: a review of work completed and description of a multisite collaborative. , 2013, Clinical therapeutics.

[11]  C. Ramsay,et al.  Interventions to improve antibiotic prescribing practices for hospital inpatients. , 2013, The Cochrane database of systematic reviews.

[12]  S. Cosgrove,et al.  Antimicrobial stewardship. , 2011, Infectious disease clinics of North America.

[13]  G. Forrest,et al.  Antimicrobial Stewardship at a Large Tertiary Care Academic Medical Center: Cost Analysis Before, During, and After a 7-Year Program , 2012, Infection Control & Hospital Epidemiology.

[14]  Edward Septimus,et al.  Antimicrobial stewardship: a collaborative partnership between infection preventionists and health care epidemiologists. , 2012, American journal of infection control.

[15]  P. Thompson,et al.  Clinical and economic outcomes of a prospective antimicrobial stewardship program. , 2012, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[16]  B. Camins,et al.  Impact of an Antimicrobial Utilization Program on Antimicrobial Use at a Large Teaching Hospital A Randomized Controlled Trial , 2009, Infection Control & Hospital Epidemiology.

[17]  V. Luther,et al.  Show Me the Money: Long-Term Financial Impact of an Antimicrobial Stewardship Program , 2012, Infection Control & Hospital Epidemiology.

[18]  G. Doern,et al.  Antimicrobial Stewardship Programs , 2013, Journal of Clinical Microbiology.

[19]  M. D. Di Pentima,et al.  Impact of Antimicrobial Stewardship Program on Vancomycin Use in a Pediatric Teaching Hospital , 2010, The Pediatric infectious disease journal.

[20]  C. Sprung,et al.  Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012 , 2013, Critical care medicine.

[21]  M. Levy,et al.  Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 , 2007, Intensive Care Medicine.

[22]  J. Jemison,et al.  Implementation of an antimicrobial stewardship program in a rural hospital. , 2012, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[23]  E. Larson,et al.  Development of an Antimicrobial Stewardship Intervention Using a Model of Actionable Feedback , 2012, Interdisciplinary perspectives on infectious diseases.