Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2
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K. Lam | C. Shoemaker | J. Tremblay | K. Perry | G. Yao | Pyung-Gang Lee | Nadja Krez | A. Rummel | M. Dong | Zheng Liu | Sicai Zhang | Hao Liu | Adina Przykopanski | Peng Chen | Rongsheng Jin | N. Krez
[1] G. Masuyer,et al. Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E , 2021, International journal of molecular sciences.
[2] Yoshiki Narimatsu,et al. Global view of human protein glycosylation pathways and functions , 2020, Nature Reviews Molecular Cell Biology.
[3] K. Lam,et al. Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells , 2020, Toxins.
[4] K. Lam,et al. Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function , 2020, Toxins.
[5] K. Lam,et al. Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins , 2020, Cell reports.
[6] M. Volteau,et al. Safety and pharmacodynamics of a novel recombinant botulinum toxin E (rBoNT-E): Results of a phase 1 study in healthy male subjects compared with abobotulinumtoxinA (Dysport®) , 2019, Journal of the Neurological Sciences.
[7] G. Schneider,et al. Structural Insights Into The Interaction Of Botulinum Neurotoxin A With Its Neuronal Receptor SV2C. , 2019, Toxicon : official journal of the International Society on Toxinology.
[8] Eric A. Johnson,et al. Botulinum neurotoxins A, B, C, E, and F preferentially enter cultured human motor neurons compared to other cultured human neuronal populations , 2019, FEBS letters.
[9] G. Masuyer,et al. Botulinum and Tetanus Neurotoxins. , 2019, Annual review of biochemistry.
[10] H. Hammad,et al. Protein crystallization promotes type 2 immunity and is reversible by antibody treatment , 2019, Science.
[11] J. Novak,et al. Glycosylation in health and disease , 2019, Nature Reviews Nephrology.
[12] Mark Elliott,et al. Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models , 2019, Science Advances.
[13] J. Krupp,et al. The Expanding Therapeutic Utility of Botulinum Neurotoxins , 2018, Toxins.
[14] G. Masuyer,et al. Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding , 2018, Toxins.
[15] K. Lam,et al. A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding , 2017, Scientific Reports.
[16] J. Krupp,et al. Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors , 2017, Nature Communications.
[17] R. Franzen,et al. Puzzling Out Synaptic Vesicle 2 Family Members Functions , 2017, Front. Mol. Neurosci..
[18] C. Montecucco,et al. Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology , 2017, Pharmacological Reviews.
[19] Martin A. Schärer,et al. Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C , 2017, Scientific Reports.
[20] K. Lam,et al. N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A , 2016, Nature Structural &Molecular Biology.
[21] D. Stern,et al. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin , 2016, Toxins.
[22] R. Zeleny,et al. Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test , 2015, Toxins.
[23] H. Bigalke,et al. Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN) , 2015, Toxins.
[24] K. Lam,et al. Architecture of the botulinum neurotoxin complex: a molecular machine for protection and delivery. , 2015, Current opinion in structural biology.
[25] K. Lam,et al. Diverse binding modes, same goal: The receptor recognition mechanism of botulinum neurotoxin. , 2015, Progress in biophysics and molecular biology.
[26] C. Montecucco,et al. Botulinum neurotoxins: genetic, structural and mechanistic insights , 2014, Nature Reviews Microbiology.
[27] Xavier Robert,et al. Deciphering key features in protein structures with the new ENDscript server , 2014, Nucleic Acids Res..
[28] J. Marks,et al. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A , 2014, FEBS letters.
[29] K. Acharya,et al. Engineered botulinum neurotoxins as new therapeutics. , 2014, Annual review of pharmacology and toxicology.
[30] T. Ceska,et al. Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A , 2013, Nature.
[31] Lei Jin,et al. Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity , 2013, PLoS pathogens.
[32] R. Berntsson,et al. Structure of dual receptor binding to botulinum neurotoxin B , 2013, Nature Communications.
[33] M. Caleo,et al. Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons , 2012, PLoS pathogens.
[34] B. Antonsson,et al. Differences in the glycosylation of recombinant proteins expressed in HEK and CHO cells. , 2012, Journal of biotechnology.
[35] D. Covas,et al. Human cells: new platform for recombinant therapeutic protein production. , 2012, Protein expression and purification.
[36] C. Shoemaker,et al. Botulinum Neurotoxin Is Shielded by NTNHA in an Interlocked Complex , 2012, Science.
[37] Eric A. Johnson,et al. Botulinum Neurotoxin D Uses Synaptic Vesicle Protein SV2 and Gangliosides as Receptors , 2011, PLoS pathogens.
[38] Eric A. Johnson,et al. SV2 Mediates Entry of Tetanus Neurotoxin into Central Neurons , 2010, PLoS pathogens.
[39] B. Spiegelman,et al. Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons , 2010, Development.
[40] Mauricio Montal,et al. Botulinum neurotoxin: a marvel of protein design. , 2010, Annual review of biochemistry.
[41] R. Jahn,et al. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation‐dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor , 2009, Journal of neurochemistry.
[42] J. Barbieri,et al. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. , 2009, Biochemistry.
[43] J. Navaza,et al. Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation. , 2008, Journal of molecular biology.
[44] Edwin R Chapman,et al. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. , 2008, Molecular biology of the cell.
[45] J. Marth,et al. Mammalian glycosylation in immunity , 2008, Nature Reviews Immunology.
[46] R. Stevens,et al. Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction , 2008, PLoS pathogens.
[47] R. Stevens,et al. Structural basis of cell surface receptor recognition by botulinum neurotoxin B , 2006, Nature.
[48] Axel T. Brunger,et al. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity , 2006, Nature.
[49] W. Jost,et al. Botulinum toxin: clinical use. , 2006, Parkinsonism & related disorders.
[50] Eric A. Johnson,et al. SV2 Is the Protein Receptor for Botulinum Neurotoxin A , 2006, Science.
[51] B. Davletov,et al. The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves , 2006, FEBS letters.
[52] G. Schiavo,et al. Presynaptic receptor arrays for clostridial neurotoxins. , 2004, Trends in microbiology.
[53] J. Jankovic,et al. Botulinum toxin in clinical practice , 2004, Journal of Neurology, Neurosurgery & Psychiatry.
[54] J. Keller,et al. Uptake of botulinum neurotoxin into cultured neurons. , 2004, Biochemistry.
[55] R. Stevens,et al. Crystal structure of botulinum neurotoxin type A and implications for toxicity , 1998, Nature Structural Biology.
[56] F. Corpet. Multiple sequence alignment with hierarchical clustering. , 1988, Nucleic acids research.
[57] C. Montecucco. How do tetanus and botulinum toxins bind to neuronal membranes , 1986 .
[58] J. Skehel,et al. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. , 2000, Annual review of biochemistry.
[59] A. Brünger. Free R value: a novel statistical quantity for assessing the accuracy of crystal structures , 1992, Nature.