White matter development in adolescence: a DTI study.

Adolescence is a unique period of physical and cognitive development that includes concurrent pubertal changes and sex-based vulnerabilities. While diffusion tensor imaging (DTI) studies show white matter maturation throughout the lifespan, the state of white matter integrity specific to adolescence is not well understood as are the contributions of puberty and sex. We performed whole-brain DTI studies of 114 children, adolescents, and adults to identify age-related changes in white matter integrity that characterize adolescence. A distinct set of regions across the brain were found to have decreasing radial diffusivity across age groups. Region of interest analyses revealed that maturation was attained by adolescence in broadly distributed association and projection fibers, including those supporting cortical and brain stem integration that may underlie known enhancements in reaction time during this period. Maturation after adolescence included association and projection tracts, including prefrontal-striatal connections, known to support top-down executive control of behavior and interhemispheric connectivity. Maturation proceeded in parallel with pubertal changes to the postpubertal stage, suggesting hormonal influences on white matter development. Females showed earlier maturation of white matter integrity compared with males. Together, these findings suggest that white matter connectivity supporting executive control of behavior is still immature in adolescence.

[1]  L. Westlye,et al.  Brain maturation in adolescence and young adulthood: regional age-related changes in cortical thickness and white matter volume and microstructure. , 2010, Cerebral cortex.

[2]  B. Luna,et al.  What has fMRI told us about the Development of Cognitive Control through Adolescence? , 2010, Brain and Cognition.

[3]  N. De Stefano,et al.  Longitudinal changes in grey and white matter during adolescence , 2010, NeuroImage.

[4]  B. Luna,et al.  The maturation of incentive processing and cognitive control , 2009, Pharmacology Biochemistry and Behavior.

[5]  Jonathan D. Power,et al.  Functional Brain Networks Develop from a “Local to Distributed” Organization , 2009, PLoS Comput. Biol..

[6]  T. Paus,et al.  Why do many psychiatric disorders emerge during adolescence? , 2008, Nature Reviews Neuroscience.

[7]  M. E. Wheeler,et al.  Maturational changes in anterior cingulate and frontoparietal recruitment support the development of error processing and inhibitory control. , 2008, Cerebral cortex.

[8]  Alain Pitiot,et al.  Growth of White Matter in the Adolescent Brain: Role of Testosterone and Androgen Receptor , 2008, The Journal of Neuroscience.

[9]  Alan C. Evans,et al.  Cerebral White Matter in Early Puberty Is Associated with Luteinizing Hormone Concentrations , 2022 .

[10]  Vincent J Schmithorst,et al.  Developmental differences in white matter architecture between boys and girls , 2008, Human brain mapping.

[11]  Alexander Leemans,et al.  Microstructural maturation of the human brain from childhood to adulthood , 2008, NeuroImage.

[12]  C. Zahn-Waxler,et al.  Disorders of childhood and adolescence: gender and psychopathology. , 2008, Annual review of clinical psychology.

[13]  Heidi Johansen-Berg,et al.  Changes in white matter microstructure during adolescence , 2008, NeuroImage.

[14]  Peter A. Calabresi,et al.  Tract probability maps in stereotaxic spaces: Analyses of white matter anatomy and tract-specific quantification , 2008, NeuroImage.

[15]  Khader M Hasan,et al.  Quantitative diffusion tensor tractography of association and projection fibers in normally developing children and adolescents. , 2007, Cerebral cortex.

[16]  M. Brammer,et al.  Linear age‐correlated functional development of right inferior fronto‐striato‐cerebellar networks during response inhibition and anterior cingulate during error‐related processes , 2007, Human brain mapping.

[17]  Heather L. Urry,et al.  Failure to Regulate: Counterproductive Recruitment of Top-Down Prefrontal-Subcortical Circuitry in Major Depression , 2007, The Journal of Neuroscience.

[18]  S. Petersen,et al.  Development of distinct control networks through segregation and integration , 2007, Proceedings of the National Academy of Sciences.

[19]  Paul M. Thompson,et al.  Sexual dimorphism of brain developmental trajectories during childhood and adolescence , 2007, NeuroImage.

[20]  Nadim Joni Shah,et al.  Visuospatial working memory and changes of the point of view in 3D space , 2007, NeuroImage.

[21]  Cheuk Y. Tang,et al.  Diffusion Tensor Anisotropy in Adolescents and Adults , 2007, Neuropsychobiology.

[22]  Timothy Edward John Behrens,et al.  Discordant white matter N-acetylasparate and diffusion MRI measures suggest that chronic metabolic dysfunction contributes to axonal pathology in multiple sclerosis , 2007, NeuroImage.

[23]  Khader M. Hasan,et al.  White matter development during late adolescence in healthy males: A cross-sectional diffusion tensor imaging study , 2007, NeuroImage.

[24]  Beatriz Luna,et al.  Circuitry underlying temporally extended spatial working memory , 2007, NeuroImage.

[25]  C. Genovese,et al.  Remapping in human visual cortex. , 2007, Journal of neurophysiology.

[26]  David Bonekamp,et al.  Diffusion tensor imaging in children and adolescents: Reproducibility, hemispheric, and age-related differences , 2007, NeuroImage.

[27]  Beatriz Luna,et al.  Cognitive processes in the development of TOL performance , 2006, Neuropsychologia.

[28]  M. Brammer,et al.  Progressive increase of frontostriatal brain activation from childhood to adulthood during event‐related tasks of cognitive control , 2006, Human brain mapping.

[29]  P. Ellen Grant,et al.  Developmental neural networks in children performing a Categorical N-Back Task , 2006, NeuroImage.

[30]  Dinggang Shen,et al.  Puberty-related influences on brain development , 2006, Molecular and Cellular Endocrinology.

[31]  Daniel Rueckert,et al.  Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data , 2006, NeuroImage.

[32]  Beatriz Luna,et al.  Brain Basis of Developmental Change in Visuospatial Working Memory , 2006, Journal of Cognitive Neuroscience.

[33]  G. Shulman,et al.  Evidence for separate perceptual reactivation and search processes during remembering. , 2006, Cerebral cortex.

[34]  Jesper Tegnér,et al.  Brain activity related to working memory and distraction in children and adults. , 2006, Cerebral cortex.

[35]  Carter Wendelken,et al.  Neurocognitive development of the ability to manipulate information in working memory. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Kristina M. Visscher,et al.  A Core System for the Implementation of Task Sets , 2006, Neuron.

[37]  K. R. Ridderinkhof,et al.  Switching between tasks and responses: a developmental study. , 2006, Developmental science.

[38]  C. Curtis.  Prefrontal and parietal contributions to spatial working memory , 2006, Neuroscience.

[39]  C. Liston,et al.  Frontostriatal microstructure modulates efficient recruitment of cognitive control. , 2006, Cerebral cortex.

[40]  N. Logothetis,et al.  Negative functional MRI response correlates with decreases in neuronal activity in monkey visual area V1 , 2006, Nature Neuroscience.

[41]  D. Pandya,et al.  Fiber Pathways of the Brain , 2006 .

[42]  P. Szeszko,et al.  MRI atlas of human white matter , 2006 .

[43]  A. Toga,et al.  Mapping brain maturation , 2006, Trends in Neurosciences.

[44]  P. Poulet,et al.  Brain dysmyelination and recovery assessment by noninvasive in vivo diffusion tensor magnetic resonance imaging , 2006, Journal of neuroscience research.

[45]  Hangyi Jiang,et al.  Pediatric diffusion tensor imaging: Normal database and observation of the white matter maturation in early childhood , 2006, NeuroImage.

[46]  V. Menon,et al.  White matter development during childhood and adolescence: a cross-sectional diffusion tensor imaging study. , 2005, Cerebral cortex.

[47]  Hoi Pang Low,et al.  Myelination and long diffusion times alter diffusion-tensor-imaging contrast in myelin-deficient shiverer mice , 2005, NeuroImage.

[48]  C. Sisk,et al.  Pubertal hormones organize the adolescent brain and behavior , 2005, Frontiers in Neuroendocrinology.

[49]  Michael G. Hardin,et al.  Triadic model of the neurobiology of motivated behavior in adolescence , 2005, Psychological Medicine.

[50]  Susan F Tapert,et al.  fMRI reveals alteration of spatial working memory networks across adolescence , 2005, Journal of the International Neuropsychological Society.

[51]  M. Brammer,et al.  Abnormal brain activation during inhibition and error detection in medication-naive adolescents with ADHD. , 2005, The American journal of psychiatry.

[52]  Jun Yoshino,et al.  Demyelination increases radial diffusivity in corpus callosum of mouse brain , 2005, NeuroImage.

[53]  S. Wakana,et al.  MRI Atlas of Human White Matter , 2005 .

[54]  Catalina J. Hooper,et al.  The development of nonverbal working memory and executive control processes in adolescents. , 2005, Child development.

[55]  Sandra Jazbec,et al.  Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents , 2005, NeuroImage.

[56]  D. Heeger,et al.  Topographic organization for delayed saccades in human posterior parietal cortex. , 2005, Journal of neurophysiology.

[57]  John E. Desmond,et al.  Load- and practice-dependent increases in cerebro-cerebellar activation in verbal working memory: an fMRI study , 2005, NeuroImage.

[58]  Mark W. Woolrich,et al.  Advances in functional and structural MR image analysis and implementation as FSL , 2004, NeuroImage.

[59]  Jens Schwarzbach,et al.  Control of object-based attention in human cortex. , 2004, Cerebral cortex.

[60]  C. Sisk,et al.  The neural basis of puberty and adolescence , 2004, Nature Neuroscience.

[61]  Robert M. Roth,et al.  The neural circuitry of reward and its relevance to psychiatric disorders , 2004, Current psychiatry reports.

[62]  G. Bohlin,et al.  Executive Functions in Children Aged 6 to 13: A Dimensional and Developmental Study , 2004, Developmental neuropsychology.

[63]  N. Lazar,et al.  Maturation of cognitive processes from late childhood to adulthood. , 2004, Child development.

[64]  T. Klingberg,et al.  Maturation of White Matter is Associated with the Development of Cognitive Functions during Childhood , 2004, Journal of Cognitive Neuroscience.

[65]  R. Dahl.  Adolescent Brain Development: A Period of Vulnerabilities and Opportunities. Keynote Address , 2004, Annals of the New York Academy of Sciences.

[66]  J. Sweeney,et al.  The Emergence of Collaborative Brain Function: fMRI Studies of the Development of Response Inhibition , 2004, Annals of the New York Academy of Sciences.

[67]  Thomas F. Nugent,et al.  Dynamic mapping of human cortical development during childhood through early adulthood. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[68]  Clayton E. Curtis,et al.  Maintenance of Spatial and Motor Codes during Oculomotor Delayed Response Tasks , 2004, The Journal of Neuroscience.

[69]  K. D. Singh,et al.  Negative BOLD in the visual cortex: Evidence against blood stealing , 2004, Human brain mapping.

[70]  K. A. Il’yasov,et al.  Fast quantitative diffusion-tensor imaging of cerebral white matter from the neonatal period to adolescence , 2004, Neuroradiology.

[71]  B. Ambridge,et al.  The structure of working memory from 4 to 15 years of age. , 2004, Developmental psychology.

[72]  Brian Knutson,et al.  Incentive-Elicited Brain Activation in Adolescents: Similarities and Differences from Young Adults , 2004, The Journal of Neuroscience.

[73]  Beatriz Luna,et al.  Eye movements in neurodevelopmental disorders , 2004, Current opinion in neurology.

[74]  L. Lotspeich,et al.  White matter structure in autism: preliminary evidence from diffusion tensor imaging , 2004, Biological Psychiatry.

[75]  Ravi S. Menon,et al.  Comparison of memory- and visually guided saccades using event-related fMRI. , 2004, Journal of neurophysiology.

[76]  T. Klingberg,et al.  Combined analysis of DTI and fMRI data reveals a joint maturation of white and grey matter in a fronto-parietal network. , 2003, Brain research. Cognitive brain research.

[77]  Derek K. Jones,et al.  Occipito-temporal connections in the human brain. , 2003, Brain : a journal of neurology.

[78]  C. Genovese,et al.  Spatial Updating in Human Parietal Cortex , 2003, Neuron.

[79]  JaneR . Taylor,et al.  Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. , 2003, The American journal of psychiatry.

[80]  C. Pantelis,et al.  Normative Data From the Cantab. I: Development of Executive Function Over the Lifespan , 2003, Journal of clinical and experimental neuropsychology.

[81]  Suzanne E. Welcome,et al.  Mapping cortical change across the human life span , 2003, Nature Neuroscience.

[82]  John Russell,et al.  Dysmyelination Revealed through MRI as Increased Radial (but Unchanged Axial) Diffusion of Water , 2002, NeuroImage.

[83]  Stephen M Smith,et al.  Fast robust automated brain extraction , 2002, Human brain mapping.

[84]  V. Menon,et al.  Maturation of brain function associated with response inhibition. , 2002, Journal of the American Academy of Child and Adolescent Psychiatry.

[85]  David C. Van Essen,et al.  Windows on the brain: the emerging role of atlases and databases in neuroscience , 2002, Current Opinion in Neurobiology.

[86]  V. Menon,et al.  Neural basis of protracted developmental changes in visuo-spatial working memory , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[87]  P. Strick,et al.  Basal-ganglia 'projections' to the prefrontal cortex of the primate. , 2002, Cerebral cortex.

[88]  Dae-Shik Kim,et al.  Origin of Negative Blood Oxygenation Level—Dependent fMRI Signals , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[89]  R. Passingham,et al.  Active maintenance in prefrontal area 46 creates distractor-resistant memory , 2002, Nature Neuroscience.

[90]  J. Gabrieli,et al.  Immature Frontal Lobe Contributions to Cognitive Control in Children Evidence from fMRI , 2002, Neuron.

[91]  T. Jernigan,et al.  Development of cortical and subcortical brain structures in childhood and adolescence: a structural MRI study , 2002, Developmental medicine and child neurology.

[92]  B. McEwen.  Invited review: Estrogens effects on the brain: multiple sites and molecular mechanisms. , 2001, Journal of applied physiology.

[93]  A. Toga,et al.  Mapping Continued Brain Growth and Gray Matter Density Reduction in Dorsal Frontal Cortex: Inverse Relationships during Postadolescent Brain Maturation , 2001, The Journal of Neuroscience.

[94]  J. Shimony,et al.  Normal brain maturation during childhood: developmental trends characterized with diffusion-tensor MR imaging. , 2001, Radiology.

[95]  M. Raichle,et al.  Searching for a baseline: Functional imaging and the resting human brain , 2001, Nature Reviews Neuroscience.

[96]  David C. Van Essen,et al.  Application of Information Technology: An Integrated Software Suite for Surface-based Analyses of Cerebral Cortex , 2001, J. Am. Medical Informatics Assoc..

[97]  Michael S. Beauchamp,et al.  A Parametric fMRI Study of Overt and Covert Shifts of Visuospatial Attention , 2001, NeuroImage.

[98]  M. Keshavan,et al.  Sex differences in brain maturation during childhood and adolescence. , 2001, Cerebral cortex.

[99]  P. Basser,et al.  Water Diffusion Changes in Wallerian Degeneration and Their Dependence on White Matter Architecture , 2000 .

[100]  Stephen M. Smith,et al.  A global optimisation method for robust affine registration of brain images , 2001, Medical Image Anal..

[101]  N. Minshew,et al.  Maturation of Widely Distributed Brain Function Subserves Cognitive Development , 2001, NeuroImage.

[102]  G. Elder,et al.  Pubertal transition, stressful life events, and the emergence of gender differences in adolescent depressive symptoms. , 2001, Developmental psychology.

[103]  J. Jonides,et al.  Overlapping mechanisms of attention and spatial working memory , 2001, Trends in Cognitive Sciences.

[104]  V. Anderson,et al.  Assessment and Development of Organizational Ability: The Rey Complex Figure Organizational Strategy Score (RCF-OSS)* , 2001, The Clinical neuropsychologist.

[105]  R. Dahl.  Affect Regulation, Brain Development, and Behavioral/Emotional Health in Adolescence , 2001, CNS Spectrums.

[106]  B. Postle,et al.  Activity in Human Frontal Cortex Associated with Spatial Working Memory and Saccadic Behavior , 2000, Journal of Cognitive Neuroscience.

[107]  L. Spear.  The adolescent brain and age-related behavioral manifestations , 2000, Neuroscience & Biobehavioral Reviews.

[108]  Nick Fogt,et al.  The Neurology of Eye Movements, 3rd ed. , 2000 .

[109]  B. Postle,et al.  Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies , 2000, Experimental Brain Research.

[110]  E. Bullmore,et al.  Functional frontalisation with age: mapping neurodevelopmental trajectories with fMRI , 2000, Neuroscience & Biobehavioral Reviews.

[111]  D. Gitelman,et al.  Neuroanatomic Overlap of Working Memory and Spatial Attention Networks: A Functional MRI Comparison within Subjects , 1999, NeuroImage.

[112]  Alan C. Evans,et al.  Brain development during childhood and adolescence: a longitudinal MRI study , 1999, Nature Neuroscience.

[113]  A. Toga,et al.  In vivo evidence for post-adolescent brain maturation in frontal and striatal regions , 1999, Nature Neuroscience.

[114]  Douglas C. Noll,et al.  A Developmental Functional MRI Study of Spatial Working Memory , 1999, NeuroImage.

[115]  H. Lee Swanson,et al.  What develops in working memory? A life span perspective. , 1999, Developmental psychology.

[116]  Jagath C. Rajapakse,et al.  Development of the human corpus callosum during childhood and adolescence: A longitudinal MRI study , 1999, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[117]  Alan C. Evans,et al.  Structural maturation of neural pathways in children and adolescents: in vivo study. , 1999, Science.

[118]  M. Corbetta,et al.  A Common Network of Functional Areas for Attention and Eye Movements , 1998, Neuron.

[119]  S. Everling,et al.  The antisaccade: a review of basic research and clinical studies , 1998, Neuropsychologia.

[120]  P. Basser,et al.  A simplified method to measure the diffusion tensor from seven MR images , 1998, Magnetic resonance in medicine.

[121]  C. Nelson,et al.  The functional emergence of prefrontally-guided working memory systems in four- to eight-year-old children , 1998, Neuropsychologia.

[122]  D. Collins,et al.  A large sex difference on a two-dimensional mental rotation task. , 1997, Behavioral neuroscience.

[123]  S. Hale,et al.  Processing Speed, Working Memory, and Fluid Intelligence: Evidence for a Developmental Cascade , 1996 .

[124]  G. Prieto,et al.  Sex differences in visuospatial ability: Do performance factors play such an important role? , 1996, Memory & cognition.

[125]  D. Heeger,et al.  Linear Systems Analysis of Functional Magnetic Resonance Imaging in Human V1 , 1996, The Journal of Neuroscience.

[126]  T. Paus.  Location and function of the human frontal eye-field: A selective review , 1996, Neuropsychologia.

[127]  A. Diamond,et al.  Development of an aspect of executive control: development of the abilities to remember what I said and to "do as I say, not as I do". , 1996, Developmental psychobiology.

[128]  J C Rajapakse,et al.  A quantitative MRI study of the corpus callosum in children and adolescents. , 1996, Brain research. Developmental brain research.

[129]  Douglas C. Noll,et al.  Activation of Prefrontal Cortex in Children during a Nonspatial Working Memory Task with Functional MRI , 1995, NeuroImage.

[130]  E. Lynd-Balta,et al.  The orbital and medial prefrontal circuit through the primate basal ganglia , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[131]  D. Mathalon,et al.  A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. , 1994, Archives of neurology.

[132]  D. Kennedy,et al.  The young adult human brain: an MRI-based morphometric analysis. , 1994, Cerebral cortex.

[133]  F. Benes,et al.  Myelination of a key relay zone in the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood. , 1994, Archives of general psychiatry.

[134]  H. Reinherz,et al.  Ages of onset of psychiatric disorders in a community population of older adolescents. , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[135]  S. Nolen-Hoeksema,et al.  The emergence of gender differences in depression during adolescence. , 1994, Psychological bulletin.

[136]  B. J. Casey,et al.  Quantitative magnetic resonance imaging of human brain development: ages 4-18. , 1996, Cerebral cortex.

[137]  R. Kail,et al.  Processing time decreases globally at an exponential rate during childhood and adolescence. , 1993, Journal of experimental child psychology.

[138]  A Capdevila,et al.  When does human brain development end? Evidence of corpus callosum growth up to adulthood , 1993, Annals of neurology.

[139]  A. Scheibel,et al.  Fiber composition of the human corpus callosum , 1992, Brain Research.

[140]  J. Arnett.  Reckless behavior in adolescence: A developmental perspective , 1992 .

[141]  Patricia S. Goldman-Rakic,et al.  The prefrontal cortex and internally generated motor acts , 1992, Current Opinion in Neurobiology.

[142]  Donald T. Stuss,et al.  Biological and psychological development of executive functions , 1992, Brain and Cognition.

[143]  Ravi S. Menon,et al.  Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[144]  R. Turner,et al.  Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[145]  P. Huttenlocher.  Morphometric study of human cerebral cortex development , 1990, Neuropsychologia.

[146]  Karl H. Pribram,et al.  Stages of Brain and Cognitive Maturation , 1990 .

[147]  S Hale,et al.  A global developmental trend in cognitive processing speed. , 1990, Child development.

[148]  P. Goldman-Rakic,et al.  Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. , 1989, Journal of neurophysiology.

[149]  P. Goldman-Rakic,et al.  Longitudinal topography and interdigitation of corticostriatal projections in the rhesus monkey , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[150]  R. Wurtz,et al.  Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses. , 1983, Journal of neurophysiology.

[151]  I. Litt,et al.  Adolescents' self-assessment of sexual maturation. , 1980, Pediatrics.

[152]  N. M. Morris,et al.  Validation of a self-administered instrument to assess stage of adolescent development , 1980, Journal of youth and adolescence.

[153]  R B Daroff,et al.  Corrective movements following refixation saccades: type and control system analysis. , 1972, Vision research.

[154]  J M Tanner,et al.  Variations in the Pattern of Pubertal Changes in Boys , 1970, Archives of disease in childhood.

[155]  J M Tanner,et al.  Variations in pattern of pubertal changes in girls. , 1969, Archives of disease in childhood.

[156]  A. Minkowski,et al.  Regional Development of the Brain in Early Life , 1968 .

[157]  P. Yakovlev,et al.  The myelogenetic cycles of regional maturation of the brain , 1967 .

[158]  B. Luna.  The Maturation of Cognitive Control and the Adolescent Brain , 2009 .

[159]  Beatriz Luna,et al.  Development of working memory maintenance. , 2009, Journal of neurophysiology.

[160]  D. Cosmelli,et al.  From attention to goal-directed behavior : neurodynamical, methodological and clinical trends , 2009 .

[161]  B. Douglas Ward,et al.  Deconvolution Analysis of FMRI Time Series Data , 2006 .

[162]  P. Goldman-Rakic,et al.  Comparison of human infants and rhesus monkeys on Piaget's AB task: evidence for dependence on dorsolateral prefrontal cortex , 2004, Experimental Brain Research.

[163]  Marko Wilke,et al.  Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study. , 2002, Radiology.

[164]  A. Demetriou,et al.  The development of mental processing: efficiency, working memory, and thinking. , 2002, Monographs of the Society for Research in Child Development.

[165]  Hans Forssberg,et al.  Increased Brain Activity in Frontal and Parietal Cortex Underlies the Development of Visuospatial Working Memory Capacity during Childhood , 2002, Journal of Cognitive Neuroscience.

[166]  L. S. Liben,et al.  The developmental course of gender differentiation: conceptualizing, measuring, and evaluating constructs and pathways. , 2002, Monographs of the Society for Research in Child Development.

[167]  J. Sweeney,et al.  Studies of brain and cognitive maturation through childhood and adolescence: a strategy for testing neurodevelopmental hypotheses. , 2001, Schizophrenia bulletin.

[168]  E. Stice,et al.  Relation of early menarche to depression, eating disorders, substance abuse, and comorbid psychopathology among adolescent girls. , 2001, Developmental psychology.

[169]  E. Rolls,et al.  Abstract reward and punishment representations in the human orbitofrontal cortex , 2001, Nature Neuroscience.

[170]  Christopher S. Monk,et al.  Functional neuroanatomy of spatial working memory in children. , 2000, Developmental psychology.

[171]  A M Dale,et al.  Optimal experimental design for event‐related fMRI , 1999, Human brain mapping.

[172]  David H. Zald,et al.  The development of spatial working memory abilities , 1998 .

[173]  A. Dale,et al.  Selective averaging of rapidly presented individual trials using fMRI , 1997, Human brain mapping.

[174]  S. Yantis,et al.  Visual attention: control, representation, and time course. , 1997, Annual review of psychology.

[175]  R. Case.  MODELING THE PROCESS OF CONCEPTUAL CHANGE IN A CONTINUOUSLY EVOLVING HIERARCHICAL SYSTEM , 1996 .

[176]  M. Mintun,et al.  Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. , 1996, Journal of neurophysiology.

[177]  K. Lloyd.  Do As I Say, Not As I Do , 1994, The Behavior analyst.

[178]  F. N. Dempster,et al.  Resistance to Interference: Developmental Changes in a Basic Processing Mechanism , 1993 .

[179]  J. Fletcher,et al.  Developmental changes in performance on tests of purported frontal lobe functioning , 1991 .

[180]  F. Benes,et al.  Myelination of cortical-hippocampal relays during late adolescence. , 1989, Schizophrenia bulletin.

[181]  P. Goldman-Rakic.  Topography of cognition: parallel distributed networks in primate association cortex. , 1988, Annual review of neuroscience.