A protocol for a randomized trial on pain neuroscience education vs. routine physical therapy in people with chronic neck pain

The aim of this study is to investigate the effects of combining routine physical therapy with pain neuroscience education (PNE) on psychosocial factors, physical performance, and the experienced pain in patients with chronic neck pain (CNP). This study is a double-blind randomized clinical trial in which patients will be randomly allocated to two groups, routine physical therapy with and without PNE. Patients will be assessed at the baseline, post intervention, and three months later. The results of this research will be used to establish effectiveness of treatment strategies for CNP. Due to the rigorous scientific methods used in this research, the suggested interventions would be clinically applicable in the health care systems.

[1]  S. Jaberzadeh,et al.  Psychometric properties of the Persian version of the brief illness questionnaire in Iranian with non-specific chronic neck pain. , 2021, Journal of bodywork and movement therapies.

[2]  S. Kahrizi,et al.  Cross-cultural adaptation and psychometric validation of the Persian version of the central sensitization inventory. , 2020, Musculoskeletal science & practice.

[3]  Anabela G. Silva,et al.  Pressure pain thresholds in university students with undertreated neck pain: comparison with asymptomatic individuals, reliability and measurement error , 2020, European Journal of Physiotherapy.

[4]  R. Gatchel,et al.  Central Sensitization in Chronic Musculoskeletal Pain Disorders in Different Populations: A Cross-Sectional Study. , 2020, Pain medicine.

[5]  Anabela G. Silva,et al.  Pain neuroscience education plus exercise compared with exercise in university students with chronic idiopathic neck pain , 2019, International Journal of Therapy and Rehabilitation.

[6]  S. Lack,et al.  Pressure pain thresholds in adults with patellofemoral pain and patellofemoral joint osteoarthritis: a case-control study , 2019, Scandinavian journal of pain.

[7]  B. Cagnie,et al.  Effect of Pain Neuroscience Education Combined With Cognition-Targeted Motor Control Training on Chronic Spinal Pain: A Randomized Clinical Trial , 2018, JAMA neurology.

[8]  C. Cook,et al.  Measurement Properties of the Central Sensitization Inventory: A Systematic Review , 2018, Pain practice : the official journal of World Institute of Pain.

[9]  J. Pool,et al.  Clinical Practice Guideline for Physical Therapy Assessment and Treatment in Patients With Nonspecific Neck Pain , 2018, Physical therapy.

[10]  J. Luciano,et al.  Dimensionality and Reliability of the Central Sensitization Inventory in a Pooled Multicountry Sample. , 2017, The journal of pain : official journal of the American Pain Society.

[11]  T. Mayer,et al.  Use of the Central Sensitization Inventory (CSI) as a treatment outcome measure for patients with chronic spinal pain disorder in a functional restoration program. , 2017, The spine journal : official journal of the North American Spine Society.

[12]  Z. Rahmati,et al.  A Study of the Psychometric Properties of the Pain Catastrophizing Scale Amongst Iranian Patients with Chronic Persistent Pain , 2017 .

[13]  R. Buchbinder,et al.  Consensus on Exercise Reporting Template (CERT): Explanation and Elaboration Statement , 2016, British Journal of Sports Medicine.

[14]  E. Broadbent,et al.  A systematic review and meta-analysis of the Brief Illness Perception Questionnaire , 2015, Psychology & health.

[15]  L. Bisset,et al.  Reliability of 2 protocols for assessing pressure pain threshold in healthy young adults. , 2015, Journal of manipulative and physiological therapeutics.

[16]  G. Vanderstraeten,et al.  Efficacy of a modern neuroscience approach versus usual care evidence-based physiotherapy on pain, disability and brain characteristics in chronic spinal pain patients: protocol of a randomized clinical trial , 2014, BMC Musculoskeletal Disorders.

[17]  J. Wyatt,et al.  Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide , 2014, BMJ : British Medical Journal.

[18]  B. Cagnie,et al.  A Modern Neuroscience Approach to Chronic Spinal Pain: Combining Pain Neuroscience Education With Cognition-Targeted Motor Control Training , 2014, Physical Therapy.

[19]  G. Moseley,et al.  How good is the neurophysiology of pain questionnaire? A Rasch analysis of psychometric properties. , 2013, The journal of pain : official journal of the American Pain Society.

[20]  D. Rennie,et al.  SPIRIT 2013 statement: defining standard protocol items for clinical trials. , 2013, Annals of internal medicine.

[21]  D. Turk,et al.  Evaluation of the psychometric properties of the revised short-form McGill Pain Questionnaire. , 2012, The journal of pain : official journal of the American Pain Society.

[22]  C. P. van Wilgen,et al.  The sensitization model to explain how chronic pain exists without tissue damage. , 2012, Pain management nursing : official journal of the American Society of Pain Management Nurses.

[23]  M. V. van Ittersum,et al.  How to explain central sensitization to patients with 'unexplained' chronic musculoskeletal pain: practice guidelines. , 2011, Manual therapy.

[24]  M. Meeus,et al.  Pain physiology education improves pain beliefs in patients with chronic fatigue syndrome compared with pacing and self-management education: a double-blind randomized controlled trial. , 2010, Archives of physical medicine and rehabilitation.

[25]  R. Oostendorp,et al.  Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice. , 2010, Manual therapy.

[26]  R. Melzack,et al.  Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2) , 2009, PAIN®.

[27]  Elizabeth Broadbent,et al.  The brief illness perception questionnaire. , 2006, Journal of psychosomatic research.

[28]  Arash Pooya,et al.  Validity and Reliability of the Short Form- 36 Items Questionnaire as a Measure of Quality of Life in Elderly Iranian Population , 2006 .

[29]  B. Gandek,et al.  The Short Form Health Survey (SF-36): Translation and validation study of the Iranian version , 2005, Quality of Life Research.

[30]  Paul W. Hodges,et al.  A Randomized Controlled Trial of Intensive Neurophysiology Education in Chronic Low Back Pain , 2004, The Clinical journal of pain.

[31]  A. Chaudhuri,et al.  Exercise lowers pain threshold in chronic fatigue syndrome , 2004, Pain.

[32]  H. Picavet,et al.  Musculoskeletal pain in the Netherlands: prevalences, consequences and risk groups, the DMC3-study , 2003, Pain.

[33]  C. Chapman,et al.  Pain measurement: an overview , 1985, Pain.