Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter
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R. Reynolds | N. Mazarakis | J. van Horssen | A. Jayaraman | R. James | C. Picón | M. Witte | Catriona Beck | Patricia Gallego
[1] Junying Yuan,et al. Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target , 2020, Nature Reviews Drug Discovery.
[2] W. Brück,et al. Molecular signature of slowly expanding lesions in progressive multiple sclerosis. , 2020, Brain : a journal of neurology.
[3] R. Reynolds,et al. The CSF profile linked to cortical damage predicts Multiple Sclerosis activity. , 2020, Annals of Neurology.
[4] R. Reynolds,et al. Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration , 2020, Acta Neuropathologica Communications.
[5] R. Reynolds,et al. Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration , 2020, Acta Neuropathologica Communications.
[6] David F. Boyd,et al. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis , 2020, Cell.
[7] C. Wegner,et al. Extensive subpial cortical demyelination is specific to multiple sclerosis , 2020, Brain pathology.
[8] T. Forsthuber,et al. TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells. , 2019, JCI insight.
[9] B. de Strooper,et al. Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer’s disease , 2019, Acta Neuropathologica.
[10] P. Durrenberger,et al. Meningeal inflammation changes the balance of TNF signalling in cortical grey matter in multiple sclerosis , 2019, Journal of Neuroinflammation.
[11] M. Maes,et al. Tumor necrosis factor alpha (TNF-α) and its soluble receptors are associated with disability, disability progression and clinical forms of multiple sclerosis , 2019, Inflammation Research.
[12] Richard Reynolds,et al. Neuronal vulnerability and multilineage diversity in multiple sclerosis , 2019, Nature.
[13] J. Pollard,et al. Central nervous system regeneration is driven by microglia necroptosis and repopulation , 2019, Nature Neuroscience.
[14] C. Hetz,et al. The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease , 2019, Cell Death & Differentiation.
[15] Junying Yuan,et al. Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases , 2018, Nature Reviews Neuroscience.
[16] Stephen E. Jones,et al. Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study , 2018, The Lancet Neurology.
[17] R. Reynolds,et al. MRI of cortical lesions and its use in studying their role in MS pathogenesis and disease course , 2018, Brain pathology.
[18] F. Facchiano,et al. Inflammatory intrathecal profiles and cortical damage in multiple sclerosis , 2018, Annals of neurology.
[19] E. Bézard,et al. Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models , 2018, Cell reports.
[20] C. V. van Eden,et al. Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis , 2018, Acta Neuropathologica.
[21] P. Vandenabeele,et al. Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis , 2018, Communications Biology.
[22] Chuan-Qi Zhong,et al. RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis , 2018, Nature Cell Biology.
[23] C. Vanhove,et al. TNFR1 inhibition with a Nanobody protects against EAE development in mice , 2017, Scientific Reports.
[24] Winnie S. Liang,et al. Necroptosis activation in Alzheimer's disease , 2017, Nature Neuroscience.
[25] Chuan-Qi Zhong,et al. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome , 2017, Nature Communications.
[26] D. Szymkowski,et al. Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination , 2016, The Journal of Neuroscience.
[27] W. Brück,et al. The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain , 2016, Brain : a journal of neurology.
[28] Snehashis Roy,et al. Association of Cortical Lesion Burden on 7-T Magnetic Resonance Imaging With Cognition and Disability in Multiple Sclerosis. , 2015, JAMA neurology.
[29] L. Probert. TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects , 2015, Neuroscience.
[30] Manuel A. Friese,et al. Immunopathology of multiple sclerosis , 2015, Nature Reviews Immunology.
[31] D. Wallach,et al. Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it , 2015, Cell Death and Differentiation.
[32] Junying Yuan,et al. Activation of necroptosis in multiple sclerosis. , 2015, Cell reports.
[33] O. Ciccarelli,et al. Exploring the origins of grey matter damage in multiple sclerosis , 2015, Nature Reviews Neuroscience.
[34] M. Bertrand,et al. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. , 2014, Cell reports.
[35] Mackenzie W. Mathis,et al. Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS , 2014, Neuron.
[36] Jiahuai Han,et al. Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death , 2013, Cell Research.
[37] Richard Reynolds,et al. Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats. , 2013, Brain : a journal of neurology.
[38] Junying Yuan,et al. Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death , 2013, Nature Reviews Molecular Cell Biology.
[39] F. Chan,et al. CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis , 2013, PloS one.
[40] Simon Hametner,et al. Disease-specific molecular events in cortical multiple sclerosis lesions , 2013, Brain : a journal of neurology.
[41] M. Santello,et al. TNFα in synaptic function: switching gears , 2012, Trends in Neurosciences.
[42] M. Calabrese,et al. Cortical lesion load associates with progression of disability in multiple sclerosis. , 2012, Brain : a journal of neurology.
[43] Samira N. Kashefi,et al. Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study , 2012, Acta Neuropathologica.
[44] Kenta Moriwaki,et al. The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis , 2012, Cell.
[45] A. Ting,et al. NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death , 2012, Immunologic Research.
[46] Xiaodong Wang,et al. Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase , 2012, Cell.
[47] Chuan-Qi Zhong,et al. Programmed necrosis: backup to and competitor with apoptosis in the immune system , 2011, Nature Immunology.
[48] R. Reynolds,et al. Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. , 2011, Brain : a journal of neurology.
[49] Theodore V. Tselios,et al. Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB. , 2011, Brain : a journal of neurology.
[50] R. Reynolds,et al. The neuropathological basis of clinical progression in multiple sclerosis , 2011, Acta Neuropathologica.
[51] R. Hakem,et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice , 2011, Nature.
[52] M. Komada,et al. Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis , 2010, Journal of neuropathology and experimental neurology.
[53] R. Reynolds,et al. A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis , 2010, Annals of neurology.
[54] P. Vandenabeele,et al. Molecular mechanisms of necroptosis: an ordered cellular explosion , 2010, Nature Reviews Molecular Cell Biology.
[55] Vishva Dixit,et al. Death receptor signal transducers: nodes of coordination in immune signaling networks , 2009, Nature Immunology.
[56] Hans Lassmann,et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains , 2009, Brain : a journal of neurology.
[57] R. Rudick,et al. Gray matter atrophy in multiple sclerosis: A longitudinal study , 2008, Annals of neurology.
[58] David H. Miller,et al. Gray matter atrophy is related to long‐term disability in multiple sclerosis , 2008, Annals of neurology.
[59] Hans Lassmann,et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. , 2005, Brain : a journal of neurology.
[60] Wolfgang Brück,et al. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. , 2002, Brain : a journal of neurology.
[61] V. Dixit,et al. Identification of a Novel Homotypic Interaction Motif Required for the Phosphorylation of Receptor-interacting Protein (RIP) by RIP3* , 2002, The Journal of Biological Chemistry.
[62] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[63] J. Ting,et al. TNFα promotes proliferation of oligodendrocyte progenitors and remyelination , 2001, Nature Neuroscience.
[64] B. Trapp,et al. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions , 2001, Annals of neurology.
[65] M. Sharief,et al. Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis , 1991 .
[66] W. Brück,et al. Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis. , 2016, Brain : a journal of neurology.
[67] F. Quintana,et al. [Immunopathology of multiple sclerosis]. , 2014, Medicina.
[68] R. Reynolds,et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. , 2007, Brain : a journal of neurology.
[69] Thomas D. Schmittgen,et al. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method , 2022 .