The discovery of novel openers of Ca2+-dependent large-conductance potassium channels: Pharmacophore search and physiological evaluation of flavonoids

[1]  V. Gribkoff,et al.  N-Benzylated benzimidazol-2-one derivatives: activators of large-conductance Ca2+-dependent K+ channels , 1996 .

[2]  V. Gribkoff,et al.  Effects of channel modulators on cloned large-conductance calcium-activated potassium channels. , 1996, Molecular pharmacology.

[3]  V. Gribkoff,et al.  Cloning and expression of a human large-conductance calcium-activated potassium channel. , 1994, Brain research. Molecular brain research.

[4]  I. Kubo,et al.  Tyrosinase inhibitory flavonoids fromheterotheca inuloides and their structural functions , 1994 .

[5]  V. Gribkoff,et al.  Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004. , 1994, Journal of neurophysiology.

[6]  S. Olesen,et al.  Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone. , 1994, European journal of pharmacology.

[7]  D. Koh,et al.  Effect of the flavoid phloretin on Ca2+-activated K+ channels in myelinated nerve fibres of Xenopus laevis , 1994, Neuroscience Letters.

[8]  L. Salkoff,et al.  mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. , 1993, Science.

[9]  O. McManus,et al.  An activator of calcium-dependent potassium channels isolated from a medicinal herb. , 1993, Biochemistry.

[10]  P. Bonnet,et al.  Evaluation of the relaxant effects of SCA40, a novel charybdotoxin‐sensitive potassium channel opener, in guinea‐pig isolated trachealis , 1993, British journal of pharmacology.

[11]  P. Erhardt,et al.  A topographical model for the c-AMP phosphodiesterase III active site. , 1991, Life sciences.

[12]  R Latorre,et al.  Varieties of calcium-activated potassium channels. , 1989, Annual review of physiology.

[13]  M. Sabio,et al.  Cardiotonic agents. 3. A topographical model of the cardiac cAMP phosphodiesterase receptor. , 1988, Molecular pharmacology.

[14]  C. Humblet,et al.  Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity. , 1987, Journal of medicinal chemistry.