Gene electrotransfer to skin; review of existing literature and clinical perspectives.
暂无分享,去创建一个
[1] J. Gehl,et al. Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice , 2010, Gene Therapy.
[2] J. Gehl,et al. Duration and level of transgene expression after gene electrotransfer to skin in mice , 2010, Gene Therapy.
[3] Richard Heller,et al. Electrically mediated delivery of plasmid DNA to the skin, using a multielectrode array. , 2010, Human gene therapy.
[4] M. Akiyama,et al. Current advances in gene therapy for the treatment of genodermatoses. , 2009, Current gene therapy.
[5] M. Čemažar,et al. Local and systemic antitumor effect of intratumoral and peritumoral IL-12 electrogene therapy on murine sarcoma , 2009, Cancer biology & therapy.
[6] T. Kivisild,et al. Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates. , 2009, Human gene therapy.
[7] J. Timmons,et al. Skin Electroporation: Effects on Transgene Expression, DNA Persistence and Local Tissue Environment , 2009, PloS one.
[8] P. Pisa,et al. Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.
[9] D. Scherman,et al. Skin-specific promoters for genetic immunisation by DNA electroporation. , 2009, Vaccine.
[10] B. Wahrén,et al. Late administration of plasmid DNA by intradermal electroporation efficiently boosts DNA-primed T and B cell responses to carcinoembryonic antigen. , 2009, Vaccine.
[11] G. Vandermeulen,et al. Effect of Tape Stripping and Adjuvants on Immune Response After Intradermal DNA Electroporation , 2009, Pharmaceutical Research.
[12] J. Gehl,et al. In Vivo Imaging of Far-red Fluorescent Proteins after DNA Electrotransfer to Muscle Tissue , 2009, Biological Procedures Online.
[13] D. Coppola,et al. Intradermal Delivery of Plasmid VEGF165 by Electroporation Promotes Wound Healing. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.
[14] Damijan Miklavcic,et al. Non invasive contact electrodes for in vivo localized cutaneous electropulsation and associated drug and nucleic acid delivery. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[15] Richard Heller,et al. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] M. Jaroszeski,et al. Comparison of electrically mediated and liposome-complexed plasmid DNA delivery to the skin , 2008, Genetic vaccines and therapy.
[17] D Miklavcic,et al. Efficiency of high- and low-voltage pulse combinations for gene electrotransfer in muscle, liver, tumor, and skin. , 2008, Human gene therapy.
[18] Julie Gehl,et al. Physiological effects of high- and low-voltage pulse combinations for gene electrotransfer in muscle. , 2008, Human gene therapy.
[19] Huafeng Zhang,et al. Age‐dependent impairment of HIF‐1α expression in diabetic mice: Correction with electroporation‐facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells , 2008, Journal of cellular physiology.
[20] T. Niidome,et al. Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex. , 2008, Cancer letters.
[21] J. L. Eberling,et al. Results from a phase I safety trial of hAADC gene therapy for Parkinson disease , 2008, Neurology.
[22] D. Weiner,et al. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. , 2008, Vaccine.
[23] Gaëlle Vandermeulen,et al. Optimisation of intradermal DNA electrotransfer for immunisation. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[24] E. Alton. Progress and Prospects: Gene Therapy Clinical Trials (Part 1) , 2007, Gene Therapy.
[25] Damijan Miklavčič,et al. A Numerical Model of Skin Electropermeabilization Based on In Vivo Experiments , 2007, Annals of Biomedical Engineering.
[26] D. Doolan,et al. Enhancement of antibody and cellular immune responses to malaria DNA vaccines by in vivo electroporation. , 2007, Vaccine.
[27] D. Shcherbo,et al. Bright far-red fluorescent protein for whole-body imaging , 2007, Nature Methods.
[28] K. Ugen,et al. Enhancement of anti-melanoma activity of a plasmid expressing HIV-1 Vpr delivered through in vivo electroporation , 2007, Cancer biology & therapy.
[29] Yilin Cao,et al. Electroporation-mediated plasmid gene transfer in rat incisional wound. , 2007, Journal of dermatological science.
[30] David Eidelberg,et al. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial , 2007, The Lancet.
[31] C. Menck,et al. On the search for skin gene therapy strategies of xeroderma pigmentosum disease. , 2007, Current gene therapy.
[32] I. Daskalov,et al. Electrochemotherapy of Mycosis fungoides by interferon-α , 2007 .
[33] J. Gehl,et al. Sensitive and precise regulation of haemoglobin after gene transfer of erythropoietin to muscle tissue using electroporation , 2007, Gene Therapy.
[34] Yuhong Xu,et al. Electric pulses applied prior to intramuscular DNA vaccination greatly improve the vaccine immunogenicity. , 2007, Vaccine.
[35] M. Jaroszeski,et al. Optimization of cutaneous electrically mediated plasmid DNA delivery using novel electrode , 2007, Gene Therapy.
[36] D. Dean,et al. Electrotransfer as a non viral method of gene delivery. , 2007, Current gene therapy.
[37] Sihong Song,et al. Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults. , 2006, Human gene therapy.
[38] N. K. Sah,et al. Structural, functional and therapeutic biology of survivin. , 2006, Cancer letters.
[39] J. Hooper,et al. Smallpox DNA vaccine delivered by novel skin electroporation device protects mice against intranasal poxvirus challenge , 2006, Vaccine.
[40] Michele De Luca,et al. Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells , 2006, Nature Medicine.
[41] R. Coombes,et al. A Phase I Study of OncoVEXGM-CSF, a Second-Generation Oncolytic Herpes Simplex Virus Expressing Granulocyte Macrophage Colony-Stimulating Factor , 2006, Clinical Cancer Research.
[42] John R. Mascola,et al. Gene transfer in humans using a conditionally replicating lentiviral vector , 2006, Proceedings of the National Academy of Sciences.
[43] S. Rosenberg,et al. Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes , 2006, Science.
[44] Kathryn L. Parsley,et al. Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[45] G. Marti,et al. Delivery of plasmid DNA expression vector for keratinocyte growth factor‐1 using electroporation to improve cutaneous wound healing in a septic rat model , 2006, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[46] E. Small,et al. A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[47] D. Stewart,et al. Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF121 (AdVEGF121) versus maximum medical treatment , 2006, Gene Therapy.
[48] Y. Glinka,et al. Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases. , 2006, Current gene therapy.
[49] Hui Lu,et al. Inhibitory effect of Ca2+ on in vivo gene transfer by electroporation , 2006, Acta Pharmacologica Sinica.
[50] P. Campochiaro,et al. Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial. , 2006, Human gene therapy.
[51] P. Pisa,et al. Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[52] M. Birnbaum,et al. False-Positive β-Galactosidase Staining in Osteoclasts by Endogenous Enzyme: Studies in Neonatal and Month-Old Wild-Type Mice , 2006, Connective tissue research.
[53] W. Mieler,et al. Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[54] N. Pavselj,et al. DNA electrotransfer into the skin using a combination of one high- and one low-voltage pulse. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[55] M. Hashida,et al. Tissue-Specific Characteristics of in Vivo Electric Gene: Transfer by Tissue and Intravenous Injection of Plasmid DNA , 2005, Pharmaceutical Research.
[56] W. Gerlach,et al. Long‐term survival and concomitant gene expression of ribozyme‐transduced CD4+ T‐lymphocytes in HIV‐infected patients , 2005, The journal of gene medicine.
[57] Jagdish Singh,et al. Skin targeted DNA vaccine delivery using electroporation in rabbits. I: efficacy. , 2005, International journal of pharmaceutics.
[58] R. Guy,et al. Physical methods for gene transfer: improving the kinetics of gene delivery into cells. , 2005, Advanced drug delivery reviews.
[59] H. Bøtker,et al. Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial. , 2005, Journal of the American College of Cardiology.
[60] G. Marti,et al. Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model , 2004, Gene Therapy.
[61] N. Romero,et al. Phase I study of dystrophin plasmid-based gene therapy in Duchenne/Becker muscular dystrophy. , 2004, Human gene therapy.
[62] Masahiro Sato,et al. Nonviral gene transfer to surface skin of mid‐gestational murine embryos by intraamniotic injection and subsequent electroporation , 2004, Molecular reproduction and development.
[63] Leaf Huang,et al. Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice. , 2004, The Journal of investigative dermatology.
[64] R. Malone,et al. Electroporation enhances transfection efficiency in murine cutaneous wounds , 2004, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[65] Lei Zhang,et al. Enhancement of the effectiveness of electroporation-augmented cutaneous DNA vaccination by a particulate adjuvant. , 2004, Bioelectrochemistry.
[66] T. Jensen. Gene transfer into human epidermis as an experimental model for somatic gene therapy. , 2004, Danish medical bulletin.
[67] T. Nishi,et al. THIS ARTICLE HAS BEEN RETRACTED In vivo transfer of a neuronal nitric oxide synthase expression vector into the rat bladder by electroporation , 2004, BJU international.
[68] L. Mir,et al. Evidence of Antiangiogenic and Antimetastatic Activities of the Recombinant Disintegrin Domain of Metargidin , 2004, Cancer Research.
[69] Steven L Jacques,et al. Confocal fluorescence spectroscopy of subcutaneous cartilage expressing green fluorescent protein versus cutaneous collagen autofluorescence. , 2004, Journal of biomedical optics.
[70] J. Clancy,et al. Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. , 2004, Chest.
[71] L. Babiuk,et al. Needle-free topical electroporation improves gene expression from plasmids administered in porcine skin. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.
[72] Brian H Annex,et al. Claudication of Vascular Endothelial Growth Factor 121 in Patients With Disabling Intermittent Disease : A Phase II Randomized , Double-Blind , Controlled Study of Adenoviral Delivery Regional Angiogenesis With Vascular Endothelial Growth Factor in Peripheral Arterial , 2003 .
[73] Cameron S. Osborne,et al. LMO2-Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1 , 2003, Science.
[74] H. Roehl,et al. Phase 1 trial of FVIII gene transfer for severe hemophilia A using a retroviral construct administered by peripheral intravenous infusion. , 2003, Blood.
[75] D. Machado-Aranda,et al. Electroporation as a method for high-level nonviral gene transfer to the lung , 2003, Gene Therapy.
[76] Natalia Vydra,et al. In vivo electroporation of the testis versus transgenic mice model in functional studies of spermatocyte‐specific hst70 gene promoter: A comparative study , 2003, Molecular reproduction and development.
[77] M. A. Liu,et al. DNA vaccines: a review , 2003, Journal of internal medicine.
[78] B. Nardelli,et al. Pharmacokinetic and Pharmacodynamic Studies of a Human Serum Albumin-Interferon-α Fusion Protein in Cynomolgus Monkeys , 2002, Journal of Pharmacology and Experimental Therapeutics.
[79] J. Kanitakis,et al. Anatomy, histology and immunohistochemistry of normal human skin. , 2002, European journal of dermatology : EJD.
[80] S. Ylä-Herttuala,et al. Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.
[81] A. Mortellaro,et al. Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning , 2002, Science.
[82] D. Coppola,et al. IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.
[83] A. Fischer,et al. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. , 2002, The New England journal of medicine.
[84] Gregor Sersa,et al. Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector , 2002, Cancer Gene Therapy.
[85] J. Miyazaki,et al. Skin-targeted gene transfer using in vivo electroporation , 2001, Gene Therapy.
[86] H. Hirai,et al. In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice , 2001, Gene Therapy.
[87] D. Treco,et al. Nonviral transfer of the gene encoding coagulation factor VIII in patients with severe hemophilia A. , 2001, The New England journal of medicine.
[88] M. Hori,et al. Electroporation-mediated gene transfer that targets glomeruli. , 2001, Journal of the American Society of Nephrology : JASN.
[89] M. Jaroszeski,et al. In vivo electroporation using an exponentially enhanced pulse: a new waveform. , 2001, DNA and cell biology.
[90] R. Malone,et al. Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization. , 2001, Molecular therapy : the journal of the American Society of Gene Therapy.
[91] R. Christensen,et al. Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes , 2000, Gene Therapy.
[92] N. Rainov. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. , 2000, Human gene therapy.
[93] F. Cardozo-Pelaez,et al. Article Commentary: The X-gal Caution in Neural Transplantation Studies , 2000, Cell transplantation.
[94] R. Malone,et al. Efficient nonviral cutaneous transfection. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.
[95] D. Gill,et al. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis , 2000, Gene Therapy.
[96] B. Meyrick,et al. Transfection of nasal mucosa with a normal alpha1-antitrypsin gene in alpha1-antitrypsin-deficient subjects: comparison with protein therapy. , 2000, Human gene therapy.
[97] F. Deist,et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. , 2000, Science.
[98] A. Tucker,et al. Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus. , 1999, The Journal of clinical investigation.
[99] M. Bureau,et al. Long-term, high level in vivo gene expression after electric pulse-mediated gene transfer into skeletal muscle. , 1998, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
[100] T. Tüting,et al. DNA immunization targeting the skin: molecular control of adaptive immunity. , 1998, The Journal of investigative dermatology.
[101] M. Rols,et al. In vivo electrically mediated protein and gene transfer in murine melanoma , 1998, Nature Biotechnology.
[102] Darius Moradpour,et al. In vivo gene electroinjection and expression in rat liver , 1996, FEBS letters.
[103] R. Hoffman,et al. Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: an approach to gene therapy of skin aging and other diseases. , 1996, Biochemical and biophysical research communications.
[104] S. Sukharev,et al. In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA. , 1991, Biochimica et biophysica acta.
[105] R. Kiessling,et al. Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma , 2009, Cancer Immunology, Immunotherapy.
[106] Jagdish Singh,et al. Delivery of DNA into skin via electroporation. , 2008, Methods in molecular biology.
[107] P. Pisa,et al. DNA vaccination for prostate cancer. , 2008, Methods in molecular biology.
[108] I. Fichtner,et al. Complete in vivo reversal of the multidrug resistance phenotype by jet-injection of anti-MDR1 short hairpin RNA-encoding plasmid DNA. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[109] G. Marti,et al. KGF-1 for wound healing in animal models. , 2008, Methods in molecular biology.
[110] Muriel Golzio,et al. New anti angiogenesis developments through electro-immunization: optimization by in vivo optical imaging of intradermal electro gene transfer. , 2007, Biochimica et biophysica acta.
[111] M. Foldvari,et al. DNA delivery for vaccination and therapeutics through the skin. , 2006, Current drug delivery.
[112] J. Miyazaki,et al. Epidermis-targeted gene transfer using in vivo electroporation. , 2005, Methods in molecular biology.
[113] J. Wolff,et al. The mechanism of naked DNA uptake and expression. , 2005, Advances in genetics.
[114] Véronique Préat,et al. Topical Gene Transfer into Rat Skin Using Electroporation , 2004, Pharmaceutical Research.
[115] Leaf Huang,et al. Enhanced cutaneous gene delivery following intradermal injection of naked DNA in a high ionic strength solution. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.
[116] D. Dean,et al. High‐level gene transfer to the cornea using electroporation , 2002, The journal of gene medicine.
[117] M. Jaroszeski,et al. Intradermal delivery of interleukin-12 plasmid DNA by in vivo electroporation. , 2001, DNA and cell biology.
[118] S. Masuda,et al. In vivo gene electroporation in skeletal muscle with special reference to the duration of gene expression. , 2001, International journal of molecular medicine.
[119] L. Taichman,et al. Epidermis as a secretory tissue: an in vitro tissue model to study keratinocyte secretion. , 1994, The Journal of investigative dermatology.