Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains
暂无分享,去创建一个
[1] C. Lyketsos,et al. Principles and management of neuropsychiatric symptoms in Alzheimer’s dementia , 2015, Alzheimer's Research & Therapy.
[2] M. Sabbagh,et al. Sensitivity to change and prediction of global change for the Alzheimer’s Questionnaire , 2015, Alzheimer's Research & Therapy.
[3] Vootele Voikar,et al. Spontaneous behavior in the social homecage discriminates strains, lesions and mutations in mice , 2014, Journal of Neuroscience Methods.
[4] Paulin Jirkof,et al. Burrowing and nest building behavior as indicators of well-being in mice , 2014, Journal of Neuroscience Methods.
[5] M. Staufenbiel,et al. Changes in Amyloid-β and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein , 2013, Science Translational Medicine.
[6] G. Rogler,et al. Burrowing is a sensitive behavioural assay for monitoring general wellbeing during dextran sulfate sodium colitis in laboratory mice , 2013, Laboratory animals.
[7] D. Borchelt,et al. Normal cognition in transgenic BRI2-Aβ mice , 2013, Molecular Neurodegeneration.
[8] D. Borchelt,et al. Thinking laterally about neurodegenerative proteinopathies. , 2013, The Journal of clinical investigation.
[9] Malaz Boustani,et al. Alzheimer's Association recommendations for operationalizing the detection of cognitive impairment during the Medicare Annual Wellness Visit in a primary care setting , 2013, Alzheimer's & Dementia.
[10] D. Borchelt,et al. Reversible Pathologic and Cognitive Phenotypes in an Inducible Model of Alzheimer-Amyloidosis , 2013, The Journal of Neuroscience.
[11] K. Blennow,et al. Mass spectrometric characterization of amyloid-β species in the 7PA2 cell model of Alzheimer's disease. , 2012, Journal of Alzheimer's disease : JAD.
[12] Jeffrey Cummings,et al. Age and rate of cognitive decline in Alzheimer disease: implications for clinical trials. , 2012, Archives of neurology.
[13] D. Dickson,et al. Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis , 2012, Alzheimer's Research & Therapy.
[14] L. D’Adamio,et al. Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia , 2012, Molecular Neurodegeneration.
[15] L. D’Adamio,et al. Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia , 2012, Molecular Neurodegeneration.
[16] Y. Shitaka,et al. Differential Effects between γ-Secretase Inhibitors and Modulators on Cognitive Function in Amyloid Precursor Protein-Transgenic and Nontransgenic Mice , 2012, The Journal of Neuroscience.
[17] M. Gallagher,et al. Episodic Memory on the Path to Alzheimer's Disease This Review Comes from a Themed Issue on Neurobiology of Disease Edited , 2022 .
[18] Kimberly Scearce-Levie,et al. Animal Models of Alzheimer's Disease: Modeling Targets, Not Disease Accelerating Drug Discovery for Alzheimer's Disease: Best Practices for Preclinical Animal Studies , 2022 .
[19] Marie-Christine Pardon,et al. A detailed analysis of the early context extinction deficits seen in APPswe/PS1dE9 female mice and their relevance to preclinical Alzheimer's disease , 2011, Behavioural Brain Research.
[20] Jiejing Xu,et al. Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease , 2011, Neuroscience Bulletin.
[21] E. Sibille,et al. Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex , 2011, Journal of Neuroscience Methods.
[22] C. Janus,et al. Sex difference in pathology and memory decline in rTg4510 mouse model of tauopathy , 2011, Neurobiology of Aging.
[23] Todd E. Golde,et al. Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift , 2011, Neuron.
[24] B. Hyman,et al. Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice , 2010, Neurobiology of Aging.
[25] K. Zahs,et al. ‘Too much good news’ – are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease? , 2010, Trends in Neurosciences.
[26] Courtney A Miller,et al. Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease , 2010, Neuropsychopharmacology.
[27] D. Dickson,et al. Massive gliosis induced by interleukin‐6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[28] Michael S. Fanselow,et al. From contextual fear to a dynamic view of memory systems , 2010, Trends in Cognitive Sciences.
[29] Phillip B. Jones,et al. A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice , 2009, The Journal of Neuroscience.
[30] C. Eckman,et al. Amyloid β and impairment in multiple memory systems in older transgenic APP TgCRND8 mice , 2009, Genes, brain, and behavior.
[31] Robert Lalonde,et al. Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease , 2009, Brain Research.
[32] T. O'Leary,et al. Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease , 2009, Behavioural Brain Research.
[33] Sylvain Rheims,et al. Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy , 2009, The Journal of Neuroscience.
[34] M. Day,et al. Correlating Efficacy in Rodent Cognition Models with in Vivo 5-Hydroxytryptamine1A Receptor Occupancy by a Novel Antagonist, (R)-N-(2-Methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane Carboxamide (WAY-101405) , 2008, Journal of Pharmacology and Experimental Therapeutics.
[35] G. Frisoni,et al. MRI of hippocampus and entorhinal cortex in mild cognitive impairment: A follow-up study , 2008, Neurobiology of Aging.
[36] Aimée A. Wong,et al. Age-related changes in visual acuity, learning and memory in C57BL/6J and DBA/2J mice , 2007, Neurobiology of Aging.
[37] V. Baumans,et al. Impact of 'living apart together' on postoperative recovery of mice compared with social and individual housing , 2007, Laboratory animals.
[38] J. George,et al. Cognitive assessment in the elderly: a review of clinical methods. , 2007, QJM : monthly journal of the Association of Physicians.
[39] T. Comery,et al. The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease , 2007, Molecular and Cellular Neuroscience.
[40] J. Collinge,et al. Targeting Cellular Prion Protein Reverses Early Cognitive Deficits and Neurophysiological Dysfunction in Prion-Infected Mice , 2007, Neuron.
[41] M. Jung,et al. Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review , 2006, Neuroscience & Biobehavioral Reviews.
[42] Jonathan J. Evans,et al. A review of screening tests for cognitive impairment , 2006, Journal of Neurology, Neurosurgery & Psychiatry.
[43] R. Deacon. Assessing nest building in mice , 2006, Nature Protocols.
[44] Inga Kadish,et al. Deposition of mouse amyloid β in human APP/PS1 double and single AD model transgenic mice , 2006, Neurobiology of Disease.
[45] R. E. Brown,et al. Visual detection, pattern discrimination and visual acuity in 14 strains of mice , 2006, Genes, brain, and behavior.
[46] M. Gallagher,et al. A specific amyloid-β protein assembly in the brain impairs memory , 2006, Nature.
[47] D. Borchelt,et al. Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.
[48] C. Janus. Search strategies used by APP transgenic mice during navigation in the Morris water maze. , 2004, Learning & memory.
[49] Joanna L. Jankowsky,et al. Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase , 2004 .
[50] D. Borchelt,et al. Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease , 2003, Journal of neuropathology and experimental neurology.
[51] S. Noy,et al. The cost of behavioral and psychological symptoms of dementia (BPSD) in community dwelling Alzheimer's disease patients , 2002, International journal of geriatric psychiatry.
[52] K. Ashe. Learning and memory in transgenic mice modeling Alzheimer's disease. , 2001, Learning & memory.
[53] D. Westaway,et al. Transgenic mouse models of Alzheimer's disease , 2001, Physiology & Behavior.
[54] M. Pahor,et al. Assessment of physical function in aging rodents: a strategy for improving preclinical testing. , 2001, Experimental aging research.
[55] M. Albert,et al. Preclinical prediction of AD using neuropsychological tests , 2001, Journal of the International Neuropsychological Society.
[56] D. Borchelt,et al. Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. , 2001, Biomolecular engineering.
[57] Y. Tasaki,et al. β-amyloid deposits in transgenic mice expressing human β-amyloid precursor protein have the same characteristics as those in Alzheimer's disease , 2001, Neuroscience.
[58] M. Staufenbiel,et al. Comparative Analysis of Amyloid-β Chemical Structure and Amyloid Plaque Morphology of Transgenic Mouse and Alzheimer's Disease Brains* , 2001, The Journal of Biological Chemistry.
[59] Glen T Prusky,et al. Reduced visual acuity impairs place but not cued learning in the Morris water task , 2000, Behavioural Brain Research.
[60] R. Douglas,et al. Behavioral assessment of visual acuity in mice and rats , 2000, Vision Research.
[61] B. Ott,et al. Cognition and behavior in patients with Alzheimer's disease. , 1999, The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia.
[62] David P. Wolfer,et al. Spatial Memory and Learning in Transgenic Mice: Fact or Artifact? , 1998, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.
[63] R. Petersen,et al. Aging, Memory, and Mild Cognitive Impairment , 1997, International Psychogeriatrics.
[64] J. Powers,et al. Diagnostic Criteria for the Neuropathologic Assessment of Alzheimer’s Disease , 1997, Neurobiology of Aging.
[65] R. Paylor,et al. Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. , 1997, Behavioral neuroscience.
[66] M. Oscar-Berman,et al. Memory deficits in Alzheimer's patients: A comprehensive review , 1992, Neuropsychology Review.
[67] M. Fanselow. Factors governing one-trial contextual conditioning , 1990 .
[68] A. Burns,et al. Psychiatric Phenomena in Alzheimer's Disease. I: Disorders of Thought Content , 1990, British Journal of Psychiatry.
[69] R. Lévy,et al. Psychiatric Phenomena in Alzheimer's Disease. IV: Disorders of Behaviour , 1990, British Journal of Psychiatry.
[70] A. Burns,et al. Psychiatric Phenomena in Alzheimer's Disease. II: Disorders of Perception , 1990, British Journal of Psychiatry.
[71] A. Burns,et al. Psychiatric Phenomena in Alzheimer's Disease. III: Disorders of Mood , 1990, British Journal of Psychiatry.
[72] D. Treit,et al. Thigmotaxis as a test for anxiolytic activity in rats , 1988, Pharmacology Biochemistry and Behavior.
[73] R. Morris. Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.
[74] B. Dudek,et al. Genetic influences on digging behaviors in mice (Mus musculus) in laboratory and seminatural settings. , 1983, Journal of comparative psychology.
[75] F. Vogel,et al. The limbic system in Alzheimer's disease. A neuropathologic investigation. , 1976, The American journal of pathology.
[76] H. Welzl,et al. Mouse models of neurodegenerative diseases: criteria and general methodology. , 2010, Methods in molecular biology.
[77] C. Janus,et al. Plaques, Tangles, and Memory Loss in Mouse Models of Neurodegeneration , 2007, Behavior genetics.
[78] R. Deacon. Burrowing in rodents: a sensitive method for detecting behavioral dysfunction , 2006, Nature Protocols.
[79] Michela Gallagher,et al. A specific amyloid-beta protein assembly in the brain impairs memory. , 2006, Nature.
[80] D. Borchelt,et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. , 2004, Human molecular genetics.
[81] D. German,et al. Mouse Models of Alzheimer's Disease: Insight into Treatment , 2004, Reviews in the neurosciences.
[82] Y. Tasaki,et al. beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease. , 2001, Neuroscience.
[83] Ove Almkvist,et al. Early diagnosis of Alzheimer dementia based on clinical and biological factors , 1999, European Archives of Psychiatry and Clinical Neuroscience.
[84] B. Tabachnick,et al. Using Multivariate Statistics , 1983 .
[85] F. James Rohlf,et al. Biometry: The Principles and Practice of Statistics in Biological Research , 1969 .