Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-Scale RNAi Research

Part I. RNAi HTS and Data Analysis: 1. Introduction to genome-scale RNAi research 2. Experimental designs 3. Data display and normalization 4. Quality control in genome-scale RNAi screens 5. Hit selection in genome-scale RNAi screens without replicates 6. Hit selection in genome-scale RNAi screens with replicates Part II. Methodological Development for Analyzing RNAi HTS Screens: 7. Statistical methods for group comparison 8. Statistical methods for assessing the size of siRNA effects.