Discovery of (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): an oral calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine.
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J. Macor | R. Schartman | G. Tong | G. Dubowchik | Laura J. Signor | R. Denton | K. Lentz | K. Santone | Guanglin Luo | Deborah Keavy | Ling Chen | J. Houston | W. Kostich | Charles M. Conway | M. Browning