BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages
暂无分享,去创建一个
Weiguo Zou | A. Lin | J. Xiang | Demin Wang | Hongyan Wang | Liansheng Zhang | Yongwei Zheng | Q. Liang | Rui Shao | Jie Li | W. Yu | Weida Yu
[1] Friedrich Paulsen,et al. Locally renewing resident synovial macrophages provide a protective barrier for the joint , 2019, Nature.
[2] E. Andreakos,et al. The many facets of macrophages in rheumatoid arthritis. , 2019, Biochemical pharmacology.
[3] R. Germain,et al. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage , 2019, Cell.
[4] J. Aguillón,et al. Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies , 2019, Front. Immunol..
[5] H. Zhang,et al. The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock , 2018, Cell Research.
[6] Wei Wei,et al. Bcl-XL and Mcl-1 upregulation by calreticulin promotes apoptosis resistance of fibroblast-like synoviocytes via activation of PI3K/Akt and STAT3 pathways in rheumatoid arthritis. , 2018, Clinical and experimental rheumatology.
[7] G. Kollias,et al. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts , 2018, Nature Communications.
[8] N. Danial,et al. BAD knockout provides metabolic seizure resistance in a genetic model of epilepsy with sudden unexplained death in epilepsy , 2018, Epilepsia.
[9] G. Haines,et al. Association of Increased F4/80high Macrophages With Suppression of Serum‐Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells , 2017, Arthritis & rheumatology.
[10] B. Ni,et al. Tumor Necrosis Factor Alpha Promotes Osteoclast Formation Via PI3K/Akt Pathway‐Mediated Blimp1 Expression Upregulation , 2017, Journal of cellular biochemistry.
[11] Leonie S. Taams,et al. MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis , 2017, Journal of autoimmunity.
[12] D. Hwang,et al. Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis , 2017, The Journal of clinical investigation.
[13] G. Firestein,et al. Immunopathogenesis of Rheumatoid Arthritis. , 2017, Immunity.
[14] C. Tsatsanis,et al. Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization , 2017, The Journal of Immunology.
[15] A. Mantovani,et al. Macrophage heterogeneity in the context of rheumatoid arthritis , 2016, Nature Reviews Rheumatology.
[16] S. Tas,et al. Targeting of proangiogenic signalling pathways in chronic inflammation , 2016, Nature Reviews Rheumatology.
[17] M. Hattori,et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis , 2015, Nature Communications.
[18] K. Jang,et al. Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation , 2016, Experimental & Molecular Medicine.
[19] L. Garrett-Sinha,et al. Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-induced arthritis , 2014, Bone Research.
[20] F. Marincola,et al. Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells , 2014, Cell Death and Differentiation.
[21] E. Hwang,et al. Platelet-derived Growth Factor-C (PDGF-C) Induces Anti-apoptotic Effects on Macrophages through Akt and Bad Phosphorylation* , 2014, The Journal of Biological Chemistry.
[22] C. King,et al. IL-21–Producing Th Cells in Immunity and Autoimmunity , 2013, The Journal of Immunology.
[23] C. Bao,et al. Deficiency of β-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation , 2013, Proceedings of the National Academy of Sciences.
[24] P. V. Schouwenburg,et al. Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis , 2013, Nature Reviews Rheumatology.
[25] Jiyan Zhang,et al. Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation , 2013, Cell.
[26] P. Tak,et al. Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis , 2012, Arthritis Research & Therapy.
[27] M. Bogyo,et al. Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model. , 2012, Arthritis and rheumatism.
[28] Georg Schett,et al. The pathogenesis of rheumatoid arthritis. , 2011, The New England journal of medicine.
[29] M. Kool,et al. A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis , 2011, Nature Genetics.
[30] D. Veale,et al. Macrophages in Synovial Inflammation , 2011, Front. Immun..
[31] S. Gay,et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis , 2011, Proceedings of the National Academy of Sciences.
[32] Zhinan Yin,et al. The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice , 2011, Science.
[33] Hong-shan Wang,et al. The adaptor protein CIKS/ACT1 is necessary for collagen-induced arthritis, and it contributes to the production of collagen-specific antibody. , 2010, Arthritis and rheumatism.
[34] K. Toellner,et al. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism , 2010, The Journal of experimental medicine.
[35] R. Hotchkiss,et al. Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. , 2010, Arthritis and rheumatism.
[36] B. Bresnihan,et al. Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers , 2009, The Journal of Rheumatology.
[37] G. Ciliberto,et al. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells , 2009, The Journal of experimental medicine.
[38] N. Danial. BAD: undertaker by night, candyman by day , 2008, Oncogene.
[39] S. R. Datta,et al. Dual role of proapoptotic BAD in insulin secretion and beta cell survival , 2008, Nature Medicine.
[40] A. Finnegan,et al. Expression of CD80/86 on B Cells Is Essential for Autoreactive T Cell Activation and the Development of Arthritis1 , 2007, The Journal of Immunology.
[41] J. Hutcheson,et al. Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis , 2007, Arthritis research & therapy.
[42] A. Koch,et al. Macrophages and their products in rheumatoid arthritis , 2007, Current opinion in rheumatology.
[43] Bo Shi,et al. Regulation of Mcl-1 expression in rheumatoid arthritis synovial macrophages. , 2006, Arthritis and rheumatism.
[44] J. Hutcheson,et al. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis. , 2006, Arthritis and rheumatism.
[45] S. Snapper,et al. A crucial role for macrophages in the pathology of K/B × N serum‐induced arthritis , 2005, European journal of immunology.
[46] Shi Wei,et al. IL-1 mediates TNF-induced osteoclastogenesis. , 2005, The Journal of clinical investigation.
[47] A. Zwinderman,et al. Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis , 2004, Annals of the rheumatic diseases.
[48] Jing Liu,et al. JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. , 2004, Molecular cell.
[49] E. Schwarz,et al. The TNF-α transgenic mouse model of inflammatory arthritis , 2003, Springer Seminars in Immunopathology.
[50] S. R. Datta,et al. Bad-deficient mice develop diffuse large B cell lymphoma , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[51] E. Clark,et al. Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF. , 2003, Blood.
[52] G. Firestein. Evolving concepts of rheumatoid arthritis , 2003, Nature.
[53] S. R. Datta,et al. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. , 2002, Developmental cell.
[54] R. Pope. Apoptosis as a therapeutic tool in rheumatoid arthritis , 2002, Nature Reviews Immunology.
[55] V. Taneja,et al. CD4 and CD8 T Cells in Susceptibility/Protection to Collagen-Induced Arthritis in HLA-DQ8-Transgenic Mice: Implications for Rheumatoid Arthritis1 , 2002, The Journal of Immunology.
[56] H. Perlman,et al. Constitutively Activated Akt-1 Is Vital for the Survival of Human Monocyte-Differentiated Macrophages , 2001, The Journal of experimental medicine.
[57] B. Bresnihan,et al. The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis. , 2000, Arthritis and rheumatism.
[58] J. Beijnen,et al. Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. , 2000, Arthritis and rheumatism.
[59] I. Wicks,et al. Collagen‐induced arthritis in C57BL/6 (H‐2b) mice: new insights into an important disease model of rheumatoid arthritis , 2000, European journal of immunology.
[60] P. Richards,et al. Liposomal clodronate eliminates synovial macrophages, reduces inflammation and ameliorates joint destruction in antigen-induced arthritis. , 1999, Rheumatology.
[61] R. Holmdahl,et al. B cell‐deficient mice do not develop type II collagen‐induced arthritis (CIA) , 1998, Clinical and experimental immunology.
[62] S. R. Datta,et al. Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery , 1997, Cell.
[63] F. Breedveld,et al. Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity. , 1997, Arthritis and rheumatism.
[64] E. Gravallese,et al. Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65. , 1995, Arthritis and rheumatism.
[65] S. Korsmeyer,et al. Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death , 1995, Cell.
[66] D. Kioussis,et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. , 1991, The EMBO journal.
[67] R. Maini,et al. Morphometric comparison of synovium from patients with osteoarthritis and rheumatoid arthritis. , 1988, Journal of clinical pathology.
[68] Samir Guglani. Death , 1890, The Lancet.
[69] John D. Isaacs,et al. Cytokines in rheumatoid arthritis — shaping the immunological landscape , 2016, Nature Reviews Rheumatology.
[70] Richard O. Williams,et al. Protocol for the induction of arthritis in C57BL/6 mice , 2008, Nature Protocols.
[71] T. Myers,et al. Expression and location of pro-apoptotic Bcl-2 family protein BAD in normal human tissues and tumor cell lines. , 1998, The American journal of pathology.
[72] R. Pemberton. Treatment of arthritis. , 1949, Pennsylvania medical journal.