Current carried by the Slc26 family member prestin does not flow through the transporter pathway

[1]  C. Rose,et al.  Glutamate transporter‐associated anion channels adjust intracellular chloride concentrations during glial maturation , 2017, Glia.

[2]  B. Byrne,et al.  Transporter oligomerization: form and function , 2016, Biochemical Society transactions.

[3]  J. Santos-Sacchi,et al.  Chloride Anions Regulate Kinetics but Not Voltage-Sensor Qmax of the Solute Carrier SLC26a5. , 2016, Biophysical journal.

[4]  A. Armstrong,et al.  Structure of eukaryotic purine/H+ symporter UapA suggests a role for homodimerization in transport activity , 2016, Nature Communications.

[5]  R. Henderson,et al.  Acquisition of Multidimensional NMR Data on GST-Fused Proteins , 2016 .

[6]  Lily S. Cheung,et al.  Structure of a eukaryotic SWEET transporter in a homotrimeric complex , 2015, Nature.

[7]  R. Dutzler,et al.  Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family , 2015, Nature Structural &Molecular Biology.

[8]  M. Reith,et al.  Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities , 2015, Journal of neurochemistry.

[9]  B. L. de Groot,et al.  Mechanisms of Anion Conduction by Coupled Glutamate Transporters , 2015, Cell.

[10]  J. Santos-Sacchi,et al.  Chloride-driven electromechanical phase lags at acoustic frequencies are generated by SLC26a5, the outer hair cell motor protein. , 2014, Biophysical journal.

[11]  M. Sturlese,et al.  Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters , 2014, Nature Communications.

[12]  J. Santos-Sacchi,et al.  Real Time Measures of Prestin Charge and Fluorescence during Plasma Membrane Trafficking Reveal Sub-Tetrameric Activity , 2013, PloS one.

[13]  A. Carruthers,et al.  Sequence Determinants of GLUT1 Oligomerization , 2013, The Journal of Biological Chemistry.

[14]  J. Santos-Sacchi,et al.  Disparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5 , 2013, Proceedings of the National Academy of Sciences.

[15]  J. Ashmore,et al.  Mammalian prestin is a weak Cl−/HCO3− electrogenic antiporter , 2012, The Journal of physiology.

[16]  Dennis C Harrison Form and function , 2012, Canadian Medical Association Journal.

[17]  C. Fahlke,et al.  Anion transport by the cochlear motor protein prestin , 2012, The Journal of physiology.

[18]  N. Yan,et al.  Structure and mechanism of the uracil transporter UraA , 2011, Nature.

[19]  I. So,et al.  Determinants of coupled transport and uncoupled current by the electrogenic SLC26 transporters , 2011, The Journal of general physiology.

[20]  J. Santos-Sacchi,et al.  A highly expressing Tet-inducible cell line recapitulates in situ developmental changes in prestin's Boltzmann characteristics and reveals early maturational events. , 2010, American journal of physiology. Cell physiology.

[21]  J. Santos-Sacchi,et al.  Conformational state-dependent anion binding in prestin: evidence for allosteric modulation. , 2010, Biophysical journal.

[22]  J. Santos-Sacchi,et al.  Prestin's anion transport and voltage-sensing capabilities are independent. , 2009, Biophysical journal.

[23]  Joseph Santos-Sacchi,et al.  Anion control of voltage sensing by the motor protein prestin in outer hair cells. , 2008, Biophysical journal.

[24]  Shmuel Muallem,et al.  The solute carrier 26 family of proteins in epithelial ion transport. , 2008, Physiology.

[25]  D. Oliver,et al.  Nonmammalian orthologs of prestin (SLC26A5) are electrogenic divalent/chloride anion exchangers , 2007, Proceedings of the National Academy of Sciences.

[26]  S. Muallem,et al.  Coupling Modes and Stoichiometry of Cl−/HCO3 − Exchange by slc26a3 and slc26a6 , 2006, The Journal of general physiology.

[27]  Joseph Santos-Sacchi,et al.  Control of Mammalian Cochlear Amplification by Chloride Anions , 2006, The Journal of Neuroscience.

[28]  J. Santos-Sacchi,et al.  On the temperature and tension dependence of the outer hair cell lateral membrane conductance GmetL and its relation to prestin , 2006, Pflügers Archiv.

[29]  J. Santos-Sacchi,et al.  On membrane motor activity and chloride flux in the outer hair cell: lessons learned from the environmental toxin tributyltin. , 2005, Biophysical journal.

[30]  M. Romero,et al.  The SLC26 gene family of multifunctional anion exchangers , 2004, Pflügers Archiv.

[31]  T. DeCoursey,et al.  Properties of Single Voltage-gated Proton Channels in Human Eosinophils Estimated by Noise Analysis and by Direct Measurement , 2003, The Journal of general physiology.

[32]  Joseph Santos-Sacchi,et al.  Cl− flux through a non‐selective, stretch‐sensitive conductance influences the outer hair cell motor of the guinea‐pig , 2003, The Journal of physiology.

[33]  Osvaldo Alvarez,et al.  Counting channels: a tutorial guide on ion channel fluctuation analysis. , 2002, Advances in physiology education.

[34]  M. Charles Liberman,et al.  Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier , 2002, Nature.

[35]  J. Santos-Sacchi,et al.  Temperature dependence of non-linear capacitance in human embryonic kidney cells transfected with prestin, the outer hair cell motor protein , 2001, Neuroscience Letters.

[36]  P Dallos,et al.  Intracellular Anions as the Voltage Sensor of Prestin, the Outer Hair Cell Motor Protein , 2001, Science.

[37]  A. Gummer,et al.  Reciprocal electromechanical properties of rat prestin: The motor molecule from rat outer hair cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[38]  J. Santos-Sacchi,et al.  Effects of membrane potential and tension on prestin, the outer hair cell lateral membrane motor protein , 2001, The Journal of physiology.

[39]  Jing Zheng,et al.  Prestin is the motor protein of cochlear outer hair cells , 2000, Nature.

[40]  G. Rudnick,et al.  Oligomerization of serotonin transporter and its functional consequences. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[41]  W Hemmert,et al.  Limiting dynamics of high-frequency electromechanical transduction of outer hair cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[42]  M. Kavanaugh,et al.  Macroscopic and Microscopic Properties of a Cloned Glutamate Transporter/Chloride Channel , 1998, The Journal of Neuroscience.

[43]  J. Santos-Sacchi,et al.  Effects of Salicylate and Lanthanides on Outer Hair Cell Motility and Associated Gating Charge , 1996, The Journal of Neuroscience.

[44]  F. Werblin,et al.  Noise analysis of the glutamate-activated current in photoreceptors. , 1996, Biophysical journal.

[45]  M. Kavanaugh,et al.  Ion fluxes associated with excitatory amino acid transport , 1995, Neuron.

[46]  J. Ashmore,et al.  Action of salicylate on membrane capacitance of outer hair cells from the guinea‐pig cochlea. , 1995, The Journal of physiology.

[47]  J. Santos-Sacchi,et al.  Mapping the distribution of the outer hair cell motility voltage sensor by electrical amputation. , 1993, Biophysical journal.

[48]  G. Giebisch,et al.  Effects of formate and oxalate on volume absorption in rat proximal tubule. , 1992, The American journal of physiology.

[49]  Craig C. Bader,et al.  Evoked mechanical responses of isolated cochlear outer hair cells. , 1985, Science.

[50]  Hallowell Davis,et al.  An active process in cochlear mechanics , 1983, Hearing Research.

[51]  F. Sigworth The variance of sodium current fluctuations at the node of Ranvier , 1980, The Journal of physiology.

[52]  J. Carver,et al.  Inhibition of Cl− binding to anion transport protein of the red blood cell by dids (4,4′-diisothiocyano-2,2′-stilbene disulfonic acid) measured by [35Cl]NMR , 1977 .

[53]  K. Beisel,et al.  From zebrafish to mammal: functional evolution of prestin, the motor protein of cochlear outer hair cells. , 2011, Journal of neurophysiology.

[54]  S. Alper The band 3-related anion exchanger (AE) gene family. , 1991, Annual review of physiology.

[55]  J. Carver,et al.  Inhibition of C1- binding to anion transport protein of the red blood cell by DIDS (4, 4'-diisothiocyano-2, 2'-stilbene disulfonic acid) measured by [35C1]NMR. , 1976, Biochemical and biophysical research communications.