Cloning and characterization of mouse 5'-AMP-activated protein kinase γ3 subunit

Naturally occurring mutations in the regulatory γ-subunit of 5′-AMP-activated protein kinase (AMPK) can result in pronounced pathological changes that may stem from increases in muscle glycogen lev...

[1]  N. Jessen,et al.  Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles. , 2003, Journal of applied physiology.

[2]  P. Neufer,et al.  AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle. , 2002, American journal of physiology. Endocrinology and metabolism.

[3]  J. Zierath,et al.  Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction. , 2002, Diabetes.

[4]  W. Winder,et al.  Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle. , 2002, Journal of applied physiology.

[5]  B. Kemp,et al.  Role of 5′AMP‐activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease , 2002, The Journal of physiology.

[6]  Y. Hellsten,et al.  Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle. , 2002, American journal of physiology. Endocrinology and metabolism.

[7]  B. Canny,et al.  Progressive increase in human skeletal muscle AMPKalpha2 activity and ACC phosphorylation during exercise. , 2002, American journal of physiology. Endocrinology and metabolism.

[8]  Y. Hellsten,et al.  Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. , 2002, Diabetes.

[9]  J. Seidman,et al.  Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. , 2002, The Journal of clinical investigation.

[10]  Young-Bum Kim,et al.  Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase , 2002, Nature.

[11]  D. Hardie,et al.  AMP‐activated protein kinase: the energy charge hypothesis revisited , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.

[12]  L. Fananapazir,et al.  Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. , 2001, The New England journal of medicine.

[13]  M. Rothschild,et al.  Evidence for new alleles in the protein kinase adenosine monophosphate-activated gamma(3)-subunit gene associated with low glycogen content in pig skeletal muscle and improved meat quality. , 2001, Genetics.

[14]  A. Depaoli-Roach,et al.  The Muscle-specific Protein Phosphatase PP1G/RGL(GM) Is Essential for Activation of Glycogen Synthase by Exercise* , 2001, The Journal of Biological Chemistry.

[15]  Wenbo Yang,et al.  Regulation of Transcription by AMP-activated Protein Kinase , 2001, The Journal of Biological Chemistry.

[16]  L. Goodyear,et al.  Increased Adenosine Monophosphate–Activated Protein Kinase Activity in Rat Hearts With Pressure-Overload Hypertrophy , 2001, Circulation.

[17]  W. Winder.  Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle. , 2001, Journal of applied physiology.

[18]  B. Viollet,et al.  Hepatocyte Nuclear Factor-4α Involved in Type 1 Maturity-Onset Diabetes of the Young Is a Novel Target of AMP-Activated Protein Kinase , 2001 .

[19]  M. Bucan,et al.  A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. , 2001, Molecular cell.

[20]  H. Watkins,et al.  Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis. , 2001, Human molecular genetics.

[21]  O. Ljungqvist,et al.  AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. , 2001, Diabetes.

[22]  L. Andersson.  Identification and characterization of AMPK γ3 mutations in the pig , 2001 .

[23]  N. Ruderman,et al.  Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. , 2000, Diabetes.

[24]  O. Ljungqvist,et al.  Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle. , 2000, Biochemical and biophysical research communications.

[25]  L. Goodyear.  AMP‐Activated Protein Kinase: A Critical Signaling Intermediary for Exercise‐Stimulated Glucose Transport? , 2000, Exercise and sport sciences reviews.

[26]  C. Rogel-Gaillard,et al.  A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. , 2000, Science.

[27]  D. Carling,et al.  Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. , 2000, The Biochemical journal.

[28]  D. Carling,et al.  The regulation of AMP-activated protein kinase by phosphorylation. , 2000, The Biochemical journal.

[29]  W. Winder,et al.  Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. , 1999, Journal of applied physiology.

[30]  B. Kemp,et al.  Expression of the AMP‐activated protein kinase β1 and β2 subunits in skeletal muscle , 1999 .

[31]  B. Kemp,et al.  Functional Domains of the α1 Catalytic Subunit of the AMP-activated Protein Kinase* , 1998, The Journal of Biological Chemistry.

[32]  C. Thornton,et al.  Identification of a Novel AMP-activated Protein Kinase β Subunit Isoform That Is Highly Expressed in Skeletal Muscle* , 1998, The Journal of Biological Chemistry.

[33]  D. Carling,et al.  Dual regulation of the AMP‐activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle , 1998, The EMBO journal.

[34]  D. Hardie,et al.  AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. , 1997, American journal of physiology. Endocrinology and metabolism.

[35]  B. Kemp,et al.  Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle* , 1997, The Journal of Biological Chemistry.

[36]  D. Hardie,et al.  Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. , 1997, The American journal of physiology.

[37]  S. Hawley,et al.  Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase* , 1996, The Journal of Biological Chemistry.

[38]  J. Scott,et al.  Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro. , 1996, The Journal of biological chemistry.

[39]  D. Hardie,et al.  Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. , 1996, The American journal of physiology.

[40]  D. Hardie,et al.  5′‐AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP‐activated protein kinase. Studies using bacterially expressed human protein phosphatase‐2Cα and native bovine protein phosphatase‐2Ac , 1995, FEBS letters.

[41]  F. Giorgino,et al.  Effects of contractile activity on tyrosine phosphoproteins and PI 3-kinase activity in rat skeletal muscle. , 1995, The American journal of physiology.

[42]  B. Kemp,et al.  Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. , 1994, The Journal of biological chemistry.

[43]  B. Kemp,et al.  Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. , 1994, The Journal of biological chemistry.

[44]  X. Vignon,et al.  Glycogen hyperaccumulation in white muscle fibres of RN- carrier pigs. A biochemical and ultrastructural study. , 1993, Comparative biochemistry and physiology. B, Comparative biochemistry.

[45]  D. Carling,et al.  Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. , 1989, European journal of biochemistry.

[46]  M. Carlson,et al.  Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase , 1989, Molecular and cellular biology.

[47]  N. Ruderman,et al.  Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. , 1971, The Biochemical journal.

[48]  R. Gordon,et al.  Cystathionine β‐synthase mutations in homocystinuria , 1999 .

[49]  H. Aihara,et al.  Gene transfer into muscle by electroporation in vivo. , 1998, Nature biotechnology.

[50]  A. Bateman.  The structure of a domain common to archaebacteria and the homocystinuria disease protein. , 1997, Trends in biochemical sciences.

[51]  Histochemistry Springer-Verlag.  A Histochemical and Ultrastructural Study , 1983 .

[52]  during exercise in , 2022 .