论文信息 - Nonlinear Control of Heartbeat Models

Nonlinear Control of Heartbeat Models

This paper presents a novel application of nonlinear control theory to heartbeat models. Existing heartbeat models are investigated and modified by incorporating the control input as a pacemaker to provide the control channel. A nonlinear feedback linearization technique is applied to force the output of the systems to generate artificial electrocardiogram (ECG) signal using discrete data as the reference inputs. The synthetic ECG may serve as a flexible signal source to assess the effectiveness of a diagnostic ECG signal-processing device.

Robert N. K. Loh | Witt Thanom | R. Loh | Witt Thanom

[1] D. S. Jones,et al. Differential Equations and Mathematical Biology , 1983 .

[2] Dale E. Seborg,et al. Nonlinear Process Control , 1996 .

[3] Nahum Shimkin,et al. Nonlinear Control Systems , 2008 .

[4] F. A. Roberge,et al. A cardiac pacemaker model , 2006, Medical & biological engineering.

[5] Marwan A. Simaan,et al. Estimation of systemic vascular bed parameters for artificial heart control , 1998 .

[6] E. C. Zeeman,et al. Differential equations for the heartbeat and nerve impulse , 1973 .

[7] A Ayatollahi,et al. A modified Zeeman model for producing HRV signals and its application to ECG signal generation. , 2007, Journal of theoretical biology.

[8] Jeffrey M. Hausdorff,et al. Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[9] C. M. Lim,et al. Cardiac state diagnosis using adaptive neuro-fuzzy technique. , 2006, Medical engineering & physics.

[10] P. Olver. Nonlinear Systems , 2013 .

[11] A. Isidori,et al. Asymptotic stabilization of minimum phase nonlinear systems , 1991 .

[12] J. R. Boston,et al. A Nonlinear State-Space Model of a Combined Cardiovascular System and a Rotary Pump , 2005, Proceedings of the 44th IEEE Conference on Decision and Control.

[13] Patrick E. McSharry,et al. A dynamical model for generating synthetic electrocardiogram signals , 2003, IEEE Transactions on Biomedical Engineering.