Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice.

[1]  Y. Konishi,et al.  Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. , 1997, Cancer research.

[2]  H. Ochi,et al.  Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model. , 1997, Laboratory investigation; a journal of technical methods and pathology.

[3]  S. Toyokuni,et al.  8-hydroxy-2'-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure. , 1996, The Journal of investigative dermatology.

[4]  Y. Hirouchi,et al.  AN IMMUNOHISTOCHEMICAL STUDY ON THE PROLIFERATIVE, PRENEOPLASTIC AND NEOPLASTIC HEPATOCELLULAR LESIONS BY SHORT-AND MID-TERM EXPERIMENTS IN MICE EXPOSED TO HEPATOCARCINOGENS , 1996 .

[5]  R. Cattley,et al.  CURRENT STATUS OF INTERNATIONAL STANDARDIZATION OF NOMENCLATURE AND DIAGNOSTIC CRITERIA FOR PROLIFERATIVE LESIONS OF THE LIVER IN THE MOUSE , 1996 .

[6]  T. Umemura,et al.  Oxidative DNA damage and cell proliferation in the livers of B6C3F1 mice exposed to pentachlorophenol in their diet. , 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[7]  A. Parkinson An Overview of Current Cytochrome P450 Technology for Assessing the Safety and Efficacy of New Materials , 1996, Toxicologic pathology.

[8]  J. Ward,et al.  Emerging Issues in Mouse Liver Carcinogenesis , 1996, Toxicologic pathology.

[9]  W C Willett,et al.  The causes and prevention of cancer. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[10]  J. Ward,et al.  Rapid development of hepatic tumors in transforming growth factor alpha transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by N-nitrosodiethylamine and promoted by phenobarbital. , 1994, Carcinogenesis.

[11]  J M Ward,et al.  Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. , 1994, Journal of the National Cancer Institute.

[12]  W. Haschek,et al.  Handbook of toxicologic pathology , 1991 .

[13]  B. Ames,et al.  Assays for 8-hydroxy-2'-deoxyguanosine: a biomarker of in vivo oxidative DNA damage. , 1991, Free radical biology & medicine.

[14]  T. Umemura,et al.  Formation of 8-hydroxydeoxyguanosine (8-OH-dG) in rat kidney DNA after intraperitoneal administration of ferric nitrilotriacetate (Fe-NTA). , 1990, Carcinogenesis.

[15]  D. Beer,et al.  Biological markers characterizing the development of preneoplastic and neoplastic lesions in rodent liver. , 1987, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

[16]  C. Short,et al.  Subacute toxicity of several ring-substituted dialkylanilines in the rat. , 1983, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[17]  D. Sarma,et al.  Role of acute hepatic necrosis in the induction of early steps in liver carcinogenesis by diethylnitrosamine. , 1981, Cancer research.

[18]  R. Albrecht Development of antibacterial agents of the nalidixic acid type. , 1977, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.