Surveillance and risk assessment of health screening for vaccine-preventable diseases among international students in Japan: A cross-sectional study in 2020

ABSTRACT We conducted a cross-sectional study using a structured questionnaire in three major Japanese cities from August 03 to 24, 2020 to clarify the current situation of health checkups, including vaccine-preventable diseases (VPDs), among international students at Japanese universities (JUs) and Japanese language schools (JLSs). The total response rate was 36%: 69 JUs (31%) and 137 JLSs (39%). Over 90% of these institutions conducted chest X-ray screening for tuberculosis among their students, whereas only 24.6% of JUs and 15.3% of JLSs performed general blood tests for health screening. Only 14.5% and 2.2% of the JUs and JLSs, respectively, required the submission of vaccination or antibody certificates for admission. The difficulties in requesting vaccination certificates from international students are due to poor legal requirements and concerns about rising costs for schools. From 2017 to 2019, 183 international students, principally from East Asia and Southeast Asia, were infected with VPDs, particularly tuberculosis (99 cases) and varicella (71 cases). Whereas the majority of Japanese educational institutions screen international students for tuberculosis (TB) at admission, only a few institutions request proof of antibody testing relating to other VPDs or of vaccination. These findings will help formulate guidelines for checkups related to vaccination for international students required to protect the educational institutions in Japan from the spread of VPDs. In addition, providing multifaceted social support, including financial compensation for institutions and enhanced international students’ health issues, would be helpful.

[1]  Frank Müller,et al.  Concordance of self-reported varicella history and serology among adolescent and adult refugee patients at a primary care clinic in Toronto, Canada. , 2021, Vaccine.

[2]  M. Ota,et al.  Epidemiology of tuberculosis in foreign students in Japan, 2015–2019: a comparison with the notification rates in their countries of origin , 2021, Epidemiology and Infection.

[3]  S. Jamshed,et al.  Discrepancies and Similarities in Attitudes, Beliefs, and Familiarity with Vaccination Between Religious Studies and Science Students in Malaysia: A Comparison Study , 2021, Journal of Religion and Health.

[4]  B. Zikmund‐Fisher,et al.  Vaccine Hesitancy and Concerns About Vaccine Safety and Effectiveness in Shanghai, China. , 2020, American journal of preventive medicine.

[5]  A. Ohkado,et al.  Trend and treatment outcomes of latent tuberculosis infection among migrant persons in Japan: retrospective analysis of Japan tuberculosis surveillance data , 2020, BMC Infectious Diseases.

[6]  T. Kitano Close the gap for routine mumps vaccination in Japan , 2020, Human vaccines & immunotherapeutics.

[7]  S. Kutsuna,et al.  Conjunctivitis, the key clinical characteristic of adult rubella in Japan during two large outbreaks, 2012–2013 and 2018–2019 , 2020, PloS one.

[8]  L. Wong,et al.  Vaccine hesitancy and the resurgence of vaccine preventable diseases: the way forward for Malaysia, a Southeast Asian country , 2020, Human vaccines & immunotherapeutics.

[9]  H. Nishiura,et al.  Reconstructing the population dynamics of foreign residents in Japan to estimate the prevalence of infection with Mycobacterium tuberculosis. , 2020, Journal of theoretical biology.

[10]  S. Kutsuna,et al.  Varicella in Adult Foreigners at a Referral Hospital, Central Tokyo, Japan, 2012–2016 , 2020, Emerging infectious diseases.

[11]  K. Feemster,et al.  Evaluating Variability in Immunization Requirements and Policy Among U.S. Colleges and Universities. , 2018, The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

[12]  Faseeha Noordeen,et al.  Epidemiology and factors influencing varicella infections in tropical countries including Sri Lanka , 2018, VirusDisease.

[13]  S. Beavers,et al.  US college and university student health screening requirements for tuberculosis and vaccine-preventable diseases, 2012 , 2016, Journal of American college health : J of ACH.

[14]  Kazumi Saito,et al.  [TUBERCULOSIS SCREENING BY CHEST RADIOGRAPHY AMONG INTERNATIONAL STUDENTS AT JAPANESE LANGUAGE SCHOOLS IN OSAKA CITY]. , 2015, Kekkaku : [Tuberculosis].

[15]  J. Boivin,et al.  Risk factors for susceptibility to varicella in newly arrived adult migrants in Canada , 2013, Epidemiology and Infection.

[16]  Y. Kanda,et al.  Investigation of the freely available easy-to-use software ‘EZR' for medical statistics , 2012, Bone Marrow Transplantation.

[17]  E. Walkinshaw Mandatory vaccinations: The Canadian picture , 2011, Canadian Medical Association Journal.

[18]  Lee Review of varicella zoster seroepidemiology in India and South‐east Asia , 1998, Tropical medicine & international health : TM & IH.

[19]  R. Evans European Centre for Disease Prevention and Control. , 2014, Nursing standard (Royal College of Nursing (Great Britain) : 1987).