Src kinases: a hub for NMDA receptor regulation

[1]  J. T. Hackett,et al.  Regulation of the Neuronal Nicotinic Acetylcholine Receptor by Src Family Tyrosine Kinases* , 2004, Journal of Biological Chemistry.

[2]  S. Grant,et al.  Identification of PSD-93 as a Substrate for the Src Family Tyrosine Kinase Fyn* , 2003, Journal of Biological Chemistry.

[3]  M. Salter,et al.  Interactions between Src family protein tyrosine kinases and PSD-95 , 2003, Neuropharmacology.

[4]  C L Galli,et al.  Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases , 2003, The Journal of Neuroscience.

[5]  L. Teves,et al.  Inhibition of protein kinase C reduces ischemia‐induced tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor , 2003, Journal of neurochemistry.

[6]  C. Parsons,et al.  Expression of Polyglutamine-expanded Huntingtin Induces Tyrosine Phosphorylation of N-Methyl-D-aspartate Receptors* , 2003, Journal of Biological Chemistry.

[7]  O. Arancio,et al.  Receptor protein tyrosine phosphatase α is essential for hippocampal neuronal migration and long‐term potentiation , 2003 .

[8]  J. Roder,et al.  Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons* , 2003, Journal of Biological Chemistry.

[9]  C. Thornton,et al.  H-Ras Modulates N-Methyl-D-aspartate Receptor Function via Inhibition of Src Tyrosine Kinase Activity* , 2003, Journal of Biological Chemistry.

[10]  G. Lynch,et al.  Integrins regulate NMDA receptor-mediated synaptic currents. , 2003, Journal of neurophysiology.

[11]  S. McMahon,et al.  EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing , 2003, Nature Neuroscience.

[12]  D. Ron,et al.  Pituitary Adenylate Cyclase-activating Polypeptide (PACAP(1–38)) Enhances N-Methyl-d-aspartate Receptor Function and Brain-derived Neurotrophic Factor Expression via RACK1* , 2003, The Journal of Biological Chemistry.

[13]  D. Chuang,et al.  Lithium‐induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N‐methyl‐D‐aspartate receptor‐mediated excitotoxicity , 2003, FEBS letters.

[14]  U. Gerber,et al.  Two Distinct Signaling Pathways Upregulate NMDA Receptor Responses via Two Distinct Metabotropic Glutamate Receptor Subtypes , 2002, The Journal of Neuroscience.

[15]  Ting-Fang Wang,et al.  pp60 c-src Is a Negative Regulator of Laminin-1-Mediated Neurite Outgrowth in Chick Sensory Neurons , 2002, Molecular and Cellular Neuroscience.

[16]  W. Guo,et al.  Tyrosine Phosphorylation of the NR2B Subunit of the NMDA Receptor in the Spinal Cord during the Development and Maintenance of Inflammatory Hyperalgesia , 2002, The Journal of Neuroscience.

[17]  M. Behrens,et al.  Metabotropic Glutamate Receptor 1-Induced Upregulation of NMDA Receptor Current: Mediation through the Pyk2/Src-Family Kinase Pathway in Cortical Neurons , 2002, The Journal of Neuroscience.

[18]  C. L. Kwan,et al.  Gain control of N‐methyl‐D‐aspartate receptor activity by receptor‐like protein tyrosine phosphatase α , 2002, The EMBO journal.

[19]  A. Bonci,et al.  NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1 , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[20]  Rand Askalan,et al.  Tyrosine Phosphatase STEP Is a Tonic Brake on Induction of Long-Term Potentiation , 2002, Neuron.

[21]  A. Irving,et al.  Leptin Enhances NMDA Receptor Function and Modulates Hippocampal Synaptic Plasticity , 2001, The Journal of Neuroscience.

[22]  N. Milgram,et al.  Seizure activity results in increased tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the hippocampus. , 2001, Brain research. Molecular brain research.

[23]  M. Baudry,et al.  Tyrosine phosphorylation of ionotropic glutamate receptors by Fyn or Src differentially modulates their susceptibility to calpain and enhances their binding to spectrin and PSD‐95 , 2001, Journal of neurochemistry.

[24]  K. Roche,et al.  Molecular determinants of NMDA receptor internalization , 2001, Nature Neuroscience.

[25]  P. Reddy,et al.  Polyglutamine-expanded Huntingtin Promotes Sensitization of N-Methyl-d-aspartate Receptors via Post-synaptic Density 95* , 2001, The Journal of Biological Chemistry.

[26]  G. Westbrook,et al.  A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux , 2001, Nature Neuroscience.

[27]  M. Salter,et al.  NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity , 2001, Current Opinion in Neurobiology.

[28]  J. Leonard,et al.  Identification of mouse NMDA receptor subunit NR2A C‐terminal tyrosine sites phosphorylated by coexpression with v‐Src , 2001, Journal of neurochemistry.

[29]  Elena Cattaneo,et al.  Loss of normal huntingtin function: new developments in Huntington's disease research , 2001, Trends in Neurosciences.

[30]  J. Roder,et al.  CAKβ/Pyk2 Kinase Is a Signaling Link for Induction of Long-Term Potentiation in CA1 Hippocampus , 2001, Neuron.

[31]  Shoji Komai,et al.  Characterization of Fyn-mediated Tyrosine Phosphorylation Sites on GluRε2 (NR2B) Subunit of theN-Methyl-d-aspartate Receptor* , 2001, The Journal of Biological Chemistry.

[32]  J. Bjorge,et al.  Identification of Protein-tyrosine Phosphatase 1B as the Major Tyrosine Phosphatase Activity Capable of Dephosphorylating and Activating c-Src in Several Human Breast Cancer Cell Lines* , 2000, The Journal of Biological Chemistry.

[33]  Michael E Greenberg,et al.  EphB Receptors Interact with NMDA Receptors and Regulate Excitatory Synapse Formation , 2000, Cell.

[34]  M. Brunelli,et al.  PACAP-38 enhances excitatory synaptic transmission in the rat hippocampal CA1 region. , 2000, Learning & memory.

[35]  Xin-Yun Huang,et al.  Src Tyrosine Kinase Is a Novel Direct Effector of G Proteins , 2000, Cell.

[36]  M. Baudry,et al.  Src-mediated Tyrosine Phosphorylation of NR2 Subunits of N-Methyl-d-Aspartate Receptors Protects from Calpain-mediated Truncation of Their C-terminal Domains* , 2000, The Journal of Biological Chemistry.

[37]  G. Siggins,et al.  A role for Src kinase in spontaneous epileptiform activity in the CA3 region of the hippocampus. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[38]  S. Grant,et al.  Proteomic analysis of NMDA receptor–adhesion protein signaling complexes , 2000, Nature Neuroscience.

[39]  C. Woolf,et al.  Neuronal plasticity: increasing the gain in pain. , 2000, Science.

[40]  H. Vaudry,et al.  Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. , 2000, Pharmacological reviews.

[41]  M. Mishina,et al.  The Protein-tyrosine Phosphatase PTPMEG Interacts with Glutamate Receptor δ2 and ε Subunits* , 2000, The Journal of Biological Chemistry.

[42]  H. Rauvala,et al.  High‐frequency synaptic stimulation induces association of fyn and c‐src to distinct phosphorylated components , 2000, Neuroreport.

[43]  M. Katsuki,et al.  Regulation of Long-Term Potentiation by H-Ras through NMDA Receptor Phosphorylation , 2000, The Journal of Neuroscience.

[44]  G. Superti-Furga,et al.  Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src , 2000, Nature Structural Biology.

[45]  L. Teves,et al.  Altered Association of Protein Tyrosine Kinases with Postsynaptic Densities after Transient Cerebral Ischemia in the Rat Brain , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[46]  J. Roder,et al.  Src Potentiation of NMDA Receptors in Hippocampal and Spinal Neurons Is Not Mediated by Reducing Zinc Inhibition , 1999, The Journal of Neuroscience.

[47]  C. Hisatsune,et al.  Phosphorylation–dependent interaction of the N‐methyl‐ d‐aspartate receptor ε2 subunit with phosphatidylinositol 3‐kinase , 1999 .

[48]  R. Nicoll,et al.  Long-term potentiation--a decade of progress? , 1999, Science.

[49]  L. Teves,et al.  The Effect of Transient Global Ischemia on the Interaction of Src and Fyn with the N-Methyl-d-Aspartate Receptor and Postsynaptic Densities: Possible Involvement of Src Homology 2 Domains , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[50]  M Marsh,et al.  The structural era of endocytosis. , 1999, Science.

[51]  M. Salter,et al.  Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[52]  I. Black,et al.  Brain-derived neurotrophic factor enhances association of protein tyrosine phosphatase PTP1D with the NMDA receptor subunit NR2B in the cortical postsynaptic density. , 1999, Brain research. Molecular brain research.

[53]  K. Lim,et al.  Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn , 1999, Current Biology.

[54]  S. Harrison,et al.  Crystal structures of c-Src reveal features of its autoinhibitory mechanism. , 1999, Molecular cell.

[55]  Wei Yang Lu,et al.  G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors , 1999, Nature Neuroscience.

[56]  A. Doyle.  Structure Functions , 1998, hep-ex/9812029.

[57]  Xian-Min Yu,et al.  Gain control of NMDA-receptor currents by intracellular sodium , 1998, Nature.

[58]  B. Orser,et al.  Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. , 1998, Molecular pharmacology.

[59]  J. Peacock,et al.  Protein-tyrosine Phosphatase α Regulates Src Family Kinases and Alters Cell-Substratum Adhesion* , 1998, The Journal of Biological Chemistry.

[60]  E. Kandel,et al.  Higher seizure susceptibility and enhanced tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit 2B in fyn transgenic mice. , 1998, Learning & memory.

[61]  M. Salter.  Src, N-methyl-D-aspartate (NMDA) receptors, and synaptic plasticity. , 1998, Biochemical pharmacology.

[62]  A. Levey,et al.  Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[63]  S. Traynelis,et al.  Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition , 1998, Nature Neuroscience.

[64]  C. Cartwright,et al.  RACK1, a Receptor for Activated C Kinase and a Homolog of the β Subunit of G Proteins, Inhibits Activity of Src Tyrosine Kinases and Growth of NIH 3T3 Cells , 1998, Molecular and Cellular Biology.

[65]  K. Lim,et al.  Physical and Functional Interactions between Receptor-like Protein-tyrosine Phosphatase α and p59 fyn * , 1998, The Journal of Biological Chemistry.

[66]  I. Black,et al.  BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. , 1998, Brain research. Molecular brain research.

[67]  J. Roder,et al.  Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. , 1998, Science.

[68]  R. Skoda,et al.  Leptin Receptor Immunoreactivity in Chemically Defined Target Neurons of the Hypothalamus , 1998, The Journal of Neuroscience.

[69]  J. Gurd,et al.  Transient Ischemia Differentially Increases Tyrosine Phosphorylation of NMDA Receptor Subunits 2A and 2B , 1997, Journal of neurochemistry.

[70]  I. Levitan,et al.  Tyrosine phosphorylation modulates current amplitude and kinetics of a neuronal voltage-gated potassium channel. , 1997, Journal of neurophysiology.

[71]  G. Mills,et al.  Src Kinase Activity Is Regulated by the SHP-1 Protein-tyrosine Phosphatase* , 1997, The Journal of Biological Chemistry.

[72]  K. Chung,et al.  Differentiation of central nervous system neuronal cells by fibroblast-derived growth factor requires at least two signaling pathways: roles for Ras and Src , 1997, Molecular and cellular biology.

[73]  J. Gurd,et al.  The N‐Methyl‐d‐Aspartate Receptor Subunits NR2A and NR2B Bind to the SH2 Domains of Phospholipase C‐γ , 1997 .

[74]  Michael J. Eck,et al.  Three-dimensional structure of the tyrosine kinase c-Src , 1997, Nature.

[75]  Xian-Min Yu,et al.  NMDA Channel Regulation by Channel-Associated Protein Tyrosine Kinase Src , 1997, Science.

[76]  S. Lev,et al.  A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation , 1996, Nature.

[77]  Y. Dudai,et al.  Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[78]  T. Bliss,et al.  Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[79]  Shu-Jen Chen,et al.  Protein Tyrosine Kinase‐Mediated Potentiation of Currents from Cloned NMDA Receptors , 1996, Journal of neurochemistry.

[80]  M. Cataldi,et al.  Protein-tyrosine Kinases Activate while Protein-tyrosine Phosphatases Inhibit L-type Calcium Channel Activity in Pituitary GH Cells (*) , 1996, The Journal of Biological Chemistry.

[81]  P. Seeburg,et al.  Subtype‐specific regulation of recombinant NMDA receptor‐channels by protein tyrosine kinases of the src family. , 1996, The Journal of physiology.

[82]  M. Salter,et al.  Ca(2+)-independent reduction of N-methyl-D-aspartate channel activity by protein tyrosine phosphatase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[83]  M. Greenberg,et al.  Ca2+-Dependent Routes to Ras: Mechanisms for Neuronal Survival, Differentiation, and Plasticity? , 1996, Neuron.

[84]  J. Hanke,et al.  Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor , 1996, The Journal of Biological Chemistry.

[85]  T. Nishi,et al.  Immunocytochemical localization of the striatal enriched protein tyrosine phosphatase in the rat striatum: A light and electron microscopic study with a complementary DNA-generated polyclonal antibody , 1995, Neuroscience.

[86]  C. Cartwright,et al.  Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. , 1995, Oncogene.

[87]  Takayoshi Suzuki,et al.  NMDA Receptor Subunits ϵ1 (NR2A) and ϵ2 (NR2B) Are Substrates for Fyn in the Postsynaptic Density Fraction Isolated from the Rat Brain , 1995 .

[88]  E. Kandel,et al.  Fyn tyrosine kinase is required for normal amygdala kindling , 1995, Epilepsy Research.

[89]  Stephen J. Moss,et al.  Modulation of GABAA receptors by tyrosine phosphorylation , 1995, Nature.

[90]  S. Fumagalli,et al.  Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division. , 1995, Science.

[91]  R. Huganir,et al.  Differential Tyrosine Phosphorylation of N-Methyl-D-aspartate Receptor Subunits (*) , 1995, The Journal of Biological Chemistry.

[92]  I. Black,et al.  Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[93]  M. Roussel,et al.  DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases , 1995, Molecular and cellular biology.

[94]  P. Wahle,et al.  Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[95]  H. Hanafusa,et al.  Comparative study of three protein-tyrosine phosphatases. Chicken protein-tyrosine phosphatase lambda dephosphorylates c-Src tyrosine 527. , 1994, The Journal of biological chemistry.

[96]  C. McBain,et al.  N-methyl-D-aspartic acid receptor structure and function. , 1994, Physiological reviews.

[97]  Yu Tian Wang,et al.  Regulation of NMDA receptors by tyrosine kinases and phosphatases , 1994, Nature.

[98]  M. Kennedy,et al.  The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[99]  J. Fargnoli,et al.  Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[100]  M. Resh.  Interaction of tyrosine kinase oncoproteins with cellular membranes. , 1993, Biochimica et biophysica acta.

[101]  G. Superti-Furga,et al.  Csk inhibition of c‐Src activity requires both the SH2 and SH3 domains of Src. , 1993, The EMBO journal.

[102]  T. Pawson,et al.  Regulation of c-Src tyrosine kinase activity by the Src SH2 domain. , 1993, Oncogene.

[103]  P Cicchetti,et al.  Identification of a ten-amino acid proline-rich SH3 binding site. , 1993, Science.

[104]  E. Kandel,et al.  Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. , 1992, Science.

[105]  Xinyang Zheng,et al.  Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase , 1992, Nature.

[106]  E. Kandel,et al.  Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors , 1991, Nature.

[107]  T Pawson,et al.  Src homology region 2 domains direct protein-protein interactions in signal transduction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[108]  M. Okada,et al.  A protein tyrosine kinase involved in regulation of pp60c-src function. , 1989, The Journal of biological chemistry.

[109]  T Pawson,et al.  A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps , 1986, Molecular and cellular biology.

[110]  Jonathan A. Cooper,et al.  Tyr527 is phosphorylated in pp60c-src: implications for regulation. , 1986, Science.

[111]  H. Oppermann,et al.  Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src). , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[112]  H. Varmus,et al.  DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA , 1976, Nature.

[113]  Tiffany Lyle,et al.  Modulation of NMDA Receptor-Dependent Calcium Influx and Gene Expression Through EphB Receptors , 2005 .

[114]  R. Juliano,et al.  Integrin Signaling , 2005, Cancer and Metastasis Reviews.

[115]  C. Thornton,et al.  H-Ras modulates NMDA receptor function via inhibition of Src tyrosine kinase activity , 2003 .

[116]  S. Coultrap,et al.  LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1 , 2002, Nature Neuroscience.

[117]  J. Gurd,et al.  Tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor by exogenous and postsynaptic density‐associated Src‐family kinases , 2001, Journal of neurochemistry.

[118]  I. Módy.  Synaptic plasticity in kindling. , 1999, Advances in neurology.

[119]  C. Hisatsune,et al.  Phosphorylation-dependent interaction of the N-methyl-D-aspartate receptor epsilon 2 subunit with phosphatidylinositol 3-kinase. , 1999, Genes to cells : devoted to molecular & cellular mechanisms.

[120]  Mingjun Fang B.S..  Modulation of GABAA Receptor Function by Tyrosine Phosphorylation , 1998 .

[121]  G. Tong.  Excitatory synaptic transmission in hippocampal neurons , 1994 .