Embryo development and ageing in birds and mammals

The rate of ageing is a genetically influenced feature of an individual's life history that responds to selection on lifespan. Various costs presumably constrain the evolution of prolonged life, but these have not been well characterized and their general nature is unclear. The analyses presented here demonstrate a correlation among birds and mammals between rates of embryonic growth and ageing-related mortality, which are quantified by the exponents of fitted power functions. This relationship suggests that rapid early development leads to accelerated ageing, presumably by influencing some aspect of the quality of the adult individual. Although the mechanisms linking embryo growth rate and ageing are not known, a simple model of life-history optimization shows that the benefits of longer life can be balanced by connected costs of extended development.

[1]  L. Partridge,et al.  Evolution of aging: Testing the theory usingDrosophila , 1993, Genetica.

[2]  S. Gerson,et al.  DNA repair defects in stem cell function and aging. , 2005, Annual review of medicine.

[3]  R. Ricklefs,et al.  Embryonic development period and the prevalence of avian blood parasites. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[4]  G. Martin,et al.  The genetics of aging. , 2003, Annual review of genomics and human genetics.

[5]  R. Ricklefs.  Sibling Competition, Hatching Asynchrony, Incubation Period, and Lifespan in Altricial Birds , 1993 .

[6]  R. Ricklefs,et al.  Comparison of aging-related mortality among birds and mammals , 2001, Experimental Gerontology.

[7]  G. Barja.  Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production–DNA damage mechanism? , 2004, Biological reviews of the Cambridge Philosophical Society.

[8]  M. Doebeli,et al.  Experimental evolution of aging, growth, and reproduction in fruitflies. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[9]  The experimental evolution of aging in fruitflies , 1998, Experimental Gerontology.

[10]  R. Wood.  DNA repair in eukaryotes. , 1996, Annual review of biochemistry.

[11]  J. Morrison,et al.  Impact and mechanisms of fetal physiological programming. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

[12]  B. Zwaan.  The evolutionary genetics of ageing and longevity , 1999, Heredity.

[13]  Thomas E. Johnson,et al.  Evolutionary biology of aging , 1990 .

[14]  Eileen M. Crimmins,et al.  Inflammatory Exposure and Historical Changes in Human Life-Spans , 2004, Science.

[15]  T. Kirkwood,et al.  The evolution of ageing and longevity , 1979, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[16]  A. Huggett,et al.  The relationship between mammalian foetal weight and conception age , 1951, The Journal of physiology.

[17]  R. Ricklefs.  Evolutionary Theories of Aging: Confirmation of a Fundamental Prediction, with Implications for the Genetic Basis and Evolution of Life Span , 1998, The American Naturalist.

[18]  D. Promislow,et al.  Genetic variation and aging. , 1995, Annual review of genetics.

[19]  P. Armitage,et al.  Multistage models of carcinogenesis. , 1985, Environmental health perspectives.

[20]  R. Ricklefs,et al.  Biological implications of the Weibull and Gompertz models of aging. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

[21]  R. Ricklefs.  Prolonged Incubation in Pelagic Seabirds: A Comment on Boersma's Paper , 1984, The American Naturalist.

[22]  A. Sancar.  DNA repair in humans. , 1995, Annual review of genetics.

[23]  P. Abrams.  DOES INCREASED MORTALITY FAVOR THE EVOLUTION OF MORE RAPID SENESCENCE? , 1993, Evolution; international journal of organic evolution.

[24]  J. Wilmoth,et al.  Age patterns of the life table aging rate for major causes of death in Japan, 1951-1990. , 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.

[25]  B. Ames,et al.  The free radical theory of aging matures. , 1998, Physiological reviews.

[26]  S. Austad,et al.  Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials. , 1991, Journal of gerontology.

[27]  George C. Williams,et al.  PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE , 1957, Science of Aging Knowledge Environment.

[28]  W. Hamilton.  The moulding of senescence by natural selection. , 1966, Journal of theoretical biology.

[29]  Deborah A. Roach.  The Biology Of Life Span , 1992 .

[30]  V. Kannisto,et al.  The Biology of Life Span: A Quantitative Approach , 1992 .

[31]  D. Promislow.  SENESCENCE IN NATURAL POPULATIONS OF MAMMALS: A COMPARATIVE STUDY , 1991, Evolution; international journal of organic evolution.

[32]  L. Gavrilov,et al.  The reliability theory of aging and longevity. , 2001, Journal of theoretical biology.

[33]  Pat Monaghan,et al.  Growth versus lifespan: perspectives from evolutionary ecology , 2003, Experimental Gerontology.

[34]  H. Rahn,et al.  The Avian Egg: Incubation Time and Water Loss , 1974 .

[35]  R. Ricklefs.  Comparative analysis of avian embryonic growth. , 1987, The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry.

[36]  R. Ricklefs.  Intrinsic aging-related mortality in birds , 2000 .

[37]  J. Tainer,et al.  DNA repair mechanisms for the recognition and removal of damaged DNA bases. , 1999, Annual review of biophysics and biomolecular structure.