Magnetic resonance imaging of controlled release pharmaceutical dosage forms

Magnetic resonance imaging offers us a powerful non-invasive method for picturing events inside controlled-release dosage forms. It allows us to observe, follow and measure important processes, such as hydration and diffusion, that can contribute directly to the process of drug release. The potential of this technique for increasing our understanding of drug release mechanisms, and the behaviour of dosage forms in vitro and in vivo is only beginning to be exploited. The unique information obtained from MRI studies will provide important detailed knowledge in problem solving and formulation development.

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