Is increased arachidonic acid release a cause or a consequence of replicative senescence?

[1]  T. Origitano,et al.  PLA2 activity regulates Ca2+ storage-dependent cellular proliferation. , 1998, Experimental cell research.

[2]  M. J. Mueller,et al.  Transport of arachidonic acid across the neutrophil plasma membrane via a protein-facilitated mechanism. , 1998, Biochemistry.

[3]  J. J. Moreno,et al.  Role of prostaglandin H synthase-2-mediated conversion of arachidonic acid in controlling 3T6 fibroblast growth. , 1997, The American journal of physiology.

[4]  A. Lorenzini,et al.  Age-related changes in essential fatty acid metabolism in cultured rat heart myocytes. , 1997, Prostaglandins, leukotrienes, and essential fatty acids.

[5]  J. J. Moreno.  Regulation of arachidonic acid release and prostaglandin formation by cell-cell adhesive interactions in wound repair , 1996, Pflügers Archiv.

[6]  T. Eling,et al.  Prostaglandin synthase 2 expression in epidermal growth factor-dependent proliferation of mouse keratinocytes. , 1996, Archives of biochemistry and biophysics.

[7]  C. Irons,et al.  Endothelin and PDGF enhance arachidonic acid release and DNA synthesis in vascular smooth muscle cells. , 1996, The American journal of physiology.

[8]  K. Vosseller,et al.  Arachidonic acid metabolism and cell proliferation in rat mammary carcinoma cells treated with indomethacin. , 1996, Biochimica et biophysica acta.

[9]  R. Pignolo,et al.  Molecular markers of senescence in fibroblast-like cultures , 1996, Experimental Gerontology.

[10]  M. Tsujimoto,et al.  Role of ceramide in stimulation of the transcription of cytosolic phospholipase A2 and cyclooxygenase 2. , 1996, Biochemical and biophysical research communications.

[11]  A. Bielawska,et al.  Role of Ceramide in Cellular Senescence (*) , 1995, The Journal of Biological Chemistry.

[12]  D. Raederstorff,et al.  Polyunsaturated fatty acid metabolism of human skin fibroblasts during cellular aging. , 1995, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.

[13]  T. Galeotti,et al.  The role of delta-6- and delta-9-desaturase in the fatty acid metabolism of hepatomas with different growth rate. , 1994, Biochemistry and molecular biology international.

[14]  J. Fayard,et al.  Phospholipase A2 inhibitors regulate the proliferation of normal uterine cells. , 1994, European journal of pharmacology.

[15]  A. Bordoni,et al.  The effect of dietary polyenylphosphatidylcholine on microsomal delta-6-desaturase activity, fatty acid composition, and microviscosity in rat liver under oxidative stress☆ , 1993 .

[16]  L. Heppel,et al.  Stimulation of aged human lung fibroblasts by extracellular ATP via suppression of arachidonate metabolism. , 1993, The Journal of biological chemistry.

[17]  L. L. Lin,et al.  Interleukin-1 alpha induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts. , 1992, The Journal of biological chemistry.

[18]  L. Heppel,et al.  Multiple signal transduction pathways lead to extracellular ATP‐stimulated mitogenesis in mammalian cells: II. A pathway involving arachidonic acid release, prostaglandin synthesis, and cyclic AMP accumulation , 1991, Journal of cellular physiology.

[19]  T. Hori,et al.  Prostaglandins antagonize fibroblast proliferation stimulated by tumor necrosis factor. , 1991, Biochemical and biophysical research communications.

[20]  T. Hori,et al.  Possible role of prostaglandins as negative regulators in growth stimulation by tumor necrosis factor and epidermal growth factor in human fibroblasts , 1989, Journal of cellular physiology.

[21]  T. Sorger,et al.  Alterations in the responsiveness of senescent cells to growth factors. , 1989, Journal of gerontology.

[22]  A. Bordoni,et al.  Age-related changes in linoleate and α-linolenate desaturation by rat liver microsomes , 1989 .

[23]  M. Kan,et al.  In vitro proliferation and lifespan of human diploid fibroblasts in serum‐free BSA‐containing medium , 1982, Journal of cellular physiology.

[24]  V. Cristofalo,et al.  Growth regulation of WI38 cells in s serum-free medium. , 1981, Experimental cell research.

[25]  V. Cristofalo,et al.  A standard procedure for cultivating human diploid fibroblastlike cells to study cellular aging , 1980 .

[26]  L. Taylor,et al.  Alterations in prostaglandin synthesis during senescence of human lung fibroblasts , 1980, Mechanisms of Ageing and Development.

[27]  Murota Seiitsu,et al.  Effect of in vitro aging on 6-ketoprostaglandin F1α -producing activity in cultured human diploid lung fibroblasts , 1979 .

[28]  A. A. Spector,et al.  Modification of the fatty acid composition of cultured human fibroblasts. , 1979, Journal of lipid research.

[29]  V. Cristofalo,et al.  Cellular senescence and DNA synthesis. Thymidine incorporation as a measure of population age in human diploid cells. , 1973, Experimental cell research.

[30]  R. R. Brenner,et al.  Metabolism of fatty acids of the linoleic acid series in testicles of diabetic rats. , 1970, The American journal of physiology.

[31]  W. Jakoby,et al.  METABOLISM OF ETHANOLAMINE. AN ETHANOLAMINE OXIDASE. , 1964, The Journal of biological chemistry.

[32]  L. Santamaria,et al.  Research progress in organic-biological and medicinal chemistry , 1964 .

[33]  L. Hayflick,et al.  The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.

[34]  W. Stoffel,et al.  Analysis of Long-Chain Fatty Acids by Gas-Liquid Chromatography , 1959 .

[35]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.