Re view Article CHEWING GUM : A MODERN ERA OF DRUG DELIVERY

Chewing gum as a drug delivery system has many advantages over other oral dosage forms and oral rou te is the most preferred route amongst the patient and clinicians because the first pass metabolism can be avoided by the absorption of drug through buccal mucosa in the systemic circulation. It can be applied to cure and prevent the dental caries, pain, s moking cessation, obesity, xerostomia, motion sickness, acidity and specially diabetes. It has many advantages like fast onse t of action, no first pass metabolism, patient compliance, taste masking, reduced risk of erosion of gastric mucosa, overdose and s ome marketing advantages. This review indicates that further study on medicated chewing gum can be used to improve it as a modern drug delivery.

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