Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation
暂无分享,去创建一个
Roy G van Heesbeen | Daphne Lelieveld | David A. Egan | Albert J. R. Heck | Marvin E. Tanenbaum | D. Egan | A. Heck | R. Medema | J. Raaijmakers | Daphne Lelieveld | C. Lieftink | M. Tanenbaum | Roy G. H. P. van Heesbeen | Jonne A. Raaijmakers | Vincentius A. Halim | Cor Lieftink | René H. Medema | V. Halim
[1] V. Doye,et al. A Mechanism for Nuclear Positioning in Fission Yeast Based on Microtubule Pushing , 2001, The Journal of cell biology.
[2] J. Pereira-Leal,et al. Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle , 2013, Open Biology.
[3] S. Diez,et al. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. , 2003, Molecular cell.
[4] E. Peterman,et al. The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks , 2005, Nature.
[5] S. Haggarty,et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. , 1999, Science.
[6] Shan Huang,et al. Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15‐dependent drug resistance , 2014, Molecular oncology.
[7] D. Glover,et al. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles , 1995, Cell.
[8] P. Wadsworth,et al. Mitotic functions of kinesin-5. , 2010, Seminars in cell & developmental biology.
[9] Marileen Dogterom,et al. Dynamic instability of microtubules is regulated by force , 2003, The Journal of cell biology.
[10] H. Lane,et al. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo , 1995, Cell.
[11] Stefan Hümmer,et al. The Human Kinesin Kif18A Is a Motile Microtubule Depolymerase Essential for Chromosome Congression , 2007, Current Biology.
[12] Damian Szklarczyk,et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored , 2010, Nucleic Acids Res..
[13] I. Vernos,et al. The Role of Hklp2 in the Stabilization and Maintenance of Spindle Bipolarity , 2009, Current Biology.
[14] T. Magnuson,et al. Aurora-A Kinase Is Essential for Bipolar Spindle Formation and Early Development , 2008, Molecular and Cellular Biology.
[15] R. Heald,et al. Mechanisms of mitotic spindle assembly and function. , 2008, International review of cytology.
[16] D. Compton,et al. The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK , 2004, The Journal of cell biology.
[17] R. Medema,et al. A Complex of Kif18b and MCAK Promotes Microtubule Depolymerization and Is Negatively Regulated by Aurora Kinases , 2011, Current Biology.
[18] Roy G van Heesbeen,et al. Nuclear envelope‐associated dynein drives prophase centrosome separation and enables Eg5‐independent bipolar spindle formation , 2012, The EMBO journal.
[19] Yongdae Shin,et al. Kinesin-12 Kif15 Targets Kinetochore Fibers through an Intrinsic Two-Step Mechanism , 2014, Current Biology.
[20] A. Hyman,et al. Microtubule polymerases and depolymerases. , 2007, Current opinion in cell biology.
[21] J. Swedlow,et al. Aurora B regulates MCAK at the mitotic centromere. , 2004, Developmental cell.
[22] Gautier Robin,et al. In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities. , 2004, Molecular cancer therapeutics.
[23] M. Malumbres,et al. Aurora kinase A inhibitors: promising agents in antitumoral therapy , 2014, Expert opinion on therapeutic targets.
[24] M. Singleton,et al. The Kinesin-12 Kif15 is a processive track-switching tetramer , 2014, eLife.
[25] D. Compton,et al. Interplay of Microtubule Dynamics and Sliding during Bipolar Spindle Formation in Mammalian Cells , 2009, Current Biology.
[26] R. Medema,et al. Mitosis as an anti-cancer target , 2011, Oncogene.
[27] Mohan L Gupta,et al. Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle , 2006, Nature Cell Biology.
[28] Eiji Kohmura,et al. Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells* , 2003, Journal of Biological Chemistry.
[29] G. von Dassow,et al. MCAK associates with the tips of polymerizing microtubules , 2005, The Journal of cell biology.
[30] R. Ohi,et al. Microtubule-depolymerizing kinesins. , 2013, Annual review of cell and developmental biology.
[31] Mark J. Schnitzer,et al. Single kinesin molecules studied with a molecular force clamp , 1999, Nature.
[32] R. Medema,et al. Regulation of localization and activity of the microtubule depolymerase MCAK , 2011, Bioarchitecture.
[33] R. Uzbekov,et al. The Xenopus laevis Aurora-related Protein Kinase pEg2 Associates with and Phosphorylates the Kinesin-related Protein XlEg5* , 1999, The Journal of Biological Chemistry.
[34] G. Fang,et al. MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[35] P. Hergert,et al. Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments. , 2003, Molecular biology of the cell.
[36] Linda Wordeman,et al. Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells , 2014, Nature Cell Biology.
[37] A. Chakravarty,et al. MLN8054, a Small-Molecule Inhibitor of Aurora A, Causes Spindle Pole and Chromosome Congression Defects Leading to Aneuploidy , 2007, Molecular and Cellular Biology.
[38] Kathleen E. Rankin,et al. Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow , 2010, The Journal of cell biology.
[39] R. Baskin,et al. A bipolar kinesin , 1996, Nature.
[40] Timothy J. Mitchison,et al. Mitotic spindle organization by a plus-end-directed microtubule motor , 1992, Nature.
[41] Jonathon Howard,et al. Kinesin-8 Motors Act Cooperatively to Mediate Length-Dependent Microtubule Depolymerization , 2009, Cell.
[42] R. Medema,et al. Shared and separate functions of polo-like kinases and aurora kinases in cancer , 2010, Nature Reviews Cancer.
[43] S. Brunak,et al. Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis , 2010, Science Signaling.
[44] A. Hyman,et al. Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis , 2005, The Journal of cell biology.
[45] Helfrid Hochegger,et al. Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1 , 2011, The EMBO journal.
[46] R. Medema,et al. Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly , 2009, Current Biology.
[47] Roy G van Heesbeen,et al. Balanced activity of three mitotic motors is required for bipolar spindle assembly and chromosome segregation. , 2014, Cell reports.
[48] Jonathon Howard,et al. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends , 2006, Nature.
[49] Anthony A. Hyman,et al. Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner , 2006, Nature Cell Biology.
[50] T. Mitchison,et al. XKCM1: A Xenopus Kinesin-Related Protein That Regulates Microtubule Dynamics during Mitotic Spindle Assembly , 1996, Cell.
[51] E. Morrison,et al. MCAK associates with EB1 , 2008, Oncogene.
[52] Stephen R. Norris,et al. Kinesin-5 inhibitor resistance is driven by kinesin-12 , 2016, The Journal of cell biology.
[53] Oliver Rath,et al. Kinesins and cancer , 2012, Nature Reviews Cancer.
[54] P. Eyers,et al. Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics , 2011, The Journal of cell biology.
[55] Wolfgang Huber,et al. Analysis of cell-based RNAi screens , 2006, Genome Biology.
[56] Olivier Elemento,et al. Using transcriptome sequencing to identify mechanisms of drug action and resistance , 2011, Nature chemical biology.
[57] Devin K Schweppe,et al. Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells , 2011, Science Signaling.
[58] Roy G van Heesbeen,et al. Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation , 2013, Communicative & integrative biology.
[59] J. Tinevez,et al. Role of cortical tension in bleb growth , 2009, Proceedings of the National Academy of Sciences.
[60] R. Ohi,et al. Kinesin-12 Differentially Affects Spindle Assembly Depending on Its Microtubule Substrate , 2013, Current Biology.
[61] Chantal LeBlanc,et al. Kif18B interacts with EB1 and controls astral microtubule length during mitosis , 2011, Molecular biology of the cell.