The diagnostic and clinical utility of microbial cell-free DNA sequencing in a real-world setting.

[1]  P. Luethy,et al.  Clinical impact of a metagenomic microbial plasma cell-free DNA next-generation sequencing assay on treatment decisions: a single-center retrospective study , 2022, BMC Infectious Diseases.

[2]  T. Blauwkamp,et al.  Microbial Cell-Free DNA Identifies Etiology of Bloodstream Infections, Persists Longer Than Conventional Blood Cultures, and its Duration of Detection is Associated with Metastatic Infection in Patients with Staphylococcus aureus and Gram-Negative Bacteremia. , 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  Sarfraz Ahmad,et al.  Impact of Next-Generation Sequencing Cell-free Pathogen DNA Test on Antimicrobial Management in Adults with Hematological Malignancies and Transplant Recipients with Suspected Infections. , 2021, Transplantation and cellular therapy.

[4]  N. Coufal,et al.  Use of Plasma Metagenomic Next-generation Sequencing for Pathogen Identification in Pediatric Endocarditis. , 2020, The Pediatric infectious disease journal.

[5]  J. Derisi,et al.  Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids , 2020, Nature Medicine.

[6]  T. Blauwkamp,et al.  Liquid biopsy for invasive mold infections in hematopoietic cell transplant recipients with pneumonia through next-generation sequencing of microbial cell-free DNA in plasma. , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[7]  A. Jain,et al.  Multiloculated Liver Abscess Caused by Fusobacterium: Role of Karius Testing in Diagnosis , 2020, Cureus.

[8]  B. Pinsky,et al.  Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study. , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[9]  David K. Hong,et al.  Evaluation of Plasma Microbial Cell-Free DNA Sequencing to Predict Bloodstream Infection in Pediatric Patients With Relapsed or Refractory Cancer , 2019, JAMA oncology.

[10]  K. Komanduri,et al.  Next-generation sequencing of microbial cell-free DNA for rapid noninvasive diagnosis of infectious diseases in immunocompromised hosts. , 2019, F1000Research.

[11]  L. Westblade,et al.  Diagnosis and Genotyping of Coxiella burnetii Endocarditis in a Patient with Prosthetic Pulmonary Valve Replacement Using Next-Generation Sequencing of Plasma Microbial Cell-Free DNA , 2019, Open forum infectious diseases.

[12]  T. Blauwkamp,et al.  Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease , 2019, Nature Microbiology.

[13]  Wei Gu,et al.  Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection. , 2019, Annual Review of Pathology.

[14]  A. Logan,et al.  Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients , 2018, Open forum infectious diseases.

[15]  T. Blauwkamp,et al.  2294. Evaluation of the Karius Plasma Next-Generation Sequencing Cell-free Pathogen DNA Test to Determine the Etiology of Infection and Impact on Anti-Microbial Management in Patients with Severe Neutropenia and Fever , 2018, Open Forum Infectious Diseases.

[16]  T. Blauwkamp,et al.  156. Direct Detection and Quantification of Bacterial Cell-free DNA in Patients with Infective Endocarditis (IE) Using the Karius Plasma Next Generation Sequencing (NGS) Test , 2018, Open Forum Infectious Diseases.

[17]  David K. Hong,et al.  Rapid Detection of Invasive Mycobacterium chimaera Infection by Using a Novel Plasma-Based Next-Generation Sequencing Assay , 2017 .

[18]  T. Blauwkamp,et al.  The SEP-SEQ Trial: Clinical Validation of the Karius Plasma Next-Generation Sequencing Test for Pathogen Detection in Sepsis , 2017, Open Forum Infectious Diseases.