Resonance-based integrated plasmonic nanosensor for lab-on-chip applications

Abstract. An integrated plasmonic resonator was proposed and analyzed. The detection performance of our device has been numerically verified by finite-difference time-domain simulations. The spectral sensitivity obtained was found to be 700  nm/RIU, where RIU is the refractive index unit. Our proposed sensor was found to have a detection limit in the order of 10−6  RIU. The plasmonic sensor could be fabricated using focus ion beam milling. Our design leads to an ultra-compact sensor suitable for on-chip sensing applications associated with a high sensitivity. For biosensing, the proposed sensor could have the ability for a specific capture of biomolecules at the sensor surface that enables for quantification of the biomolecules.

[1]  Xudong Fan,et al.  On the performance quantification of resonant refractive index sensors. , 2008, Optics express.

[2]  Jin Tao,et al.  A subwavelength coupler-type MIM optical filter. , 2009, Optics express.

[3]  M. A. Swillam,et al.  Feedback Effects in Plasmonic Slot Waveguides Examined Using a Closed Form Model , 2012, IEEE Photonics Technology Letters.

[4]  He-Zhou Wang,et al.  The transmission characteristics of surface plasmon polaritons in ring resonator. , 2009, Optics express.

[5]  Alexey V. Krasavin,et al.  Experimental demonstration of dielectric-loaded plasmonic waveguide disk resonators at telecom wavelengths , 2011 .

[6]  Mohamed A. Swillam,et al.  Efficient broadband energy transfer via momentum matching at hybrid junctions of guided-waves , 2012 .

[7]  John A Rogers,et al.  Nanostructured plasmonic sensors. , 2008, Chemical reviews.

[8]  W. Lukosz,et al.  Principles and sensitivities of integrated optical and surface plasmon sensors for direct affinity sensing and immunosensing , 1991 .

[9]  Yi Xiong,et al.  Near-field Moiré effect mediated by surface plasmon polariton excitation. , 2007, Optics letters.

[10]  K. Vahala,et al.  High-Q surface-plasmon-polariton whispering-gallery microcavity , 2009, Nature.

[11]  Peter Bienstman,et al.  Si based waveguide and surface plasmon sensors , 2007, SPIE OPTO.

[12]  J. Homola.  Surface plasmon resonance based sensors , 2006 .

[13]  Zongfu Yu,et al.  Extraordinarily high spectral sensitivity in refractive index sensors using multiple optical modes , 2011, 2012 Conference on Lasers and Electro-Optics (CLEO).

[14]  Matthew A. Cooper,et al.  Optical biosensors in drug discovery , 2002, Nature Reviews Drug Discovery.

[15]  J. Homola.  On the sensitivity of surface plasmon resonance sensors with spectral interrogation , 1997 .

[16]  M. Ghadiri,et al.  A porous silicon-based optical interferometric biosensor. , 1997, Science.

[17]  R. V. Van Duyne,et al.  A nanoscale optical biosensor: sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles. , 2002, Journal of the American Chemical Society.