Development of recombinant hepatitis C virus with NS5A from strains of genotypes 1 and 2.

[1]  J. Bukh,et al.  Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-α. , 2011, Gastroenterology.

[2]  Jieyun Jiang,et al.  The C-Terminal α-Helix Domain of Apolipoprotein E Is Required for Interaction with Nonstructural Protein 5A and Assembly of Hepatitis C Virus , 2010, Journal of Virology.

[3]  Min Gao,et al.  Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System , 2010, Antimicrobial Agents and Chemotherapy.

[4]  Min Gao,et al.  Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect , 2010, Nature.

[5]  N. Meanwell,et al.  Identification of Hepatitis C Virus NS5A Inhibitors , 2009, Journal of Virology.

[6]  R. Bartenschlager,et al.  Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics , 2009, PLoS pathogens.

[7]  T. Wakita,et al.  Hepatitis C virus JFH‐1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation , 2008, Hepatology.

[8]  K. Ishii,et al.  Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles , 2008, Journal of Virology.

[9]  Ralf Bartenschlager,et al.  Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly , 2008, PLoS pathogens.

[10]  J. Dubuisson,et al.  CD81 Expression Is Important for the Permissiveness of Huh7 Cell Clones for Heterogeneous Hepatitis C Virus Infection , 2007, Journal of Virology.

[11]  S. Lemon,et al.  Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[12]  R. Bartenschlager,et al.  Production of infectious hepatitis C virus in tissue culture from a cloned viral genome , 2005, Nature Medicine.

[13]  D. Burton,et al.  Robust hepatitis C virus infection in vitro. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  R. Bartenschlager,et al.  Efficient Rescue of Hepatitis C Virus RNA Replication by trans-Complementation with Nonstructural Protein 5A , 2005, Journal of Virology.

[15]  C. Rice,et al.  Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[16]  R H Purcell,et al.  Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras. , 1999, Virology.

[17]  J. Silver,et al.  Replication of Subgenomic Hepatitis C Virus Rnas in a Hepatoma Cell Line , 1999 .

[18]  M. Yanagi,et al.  Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[19]  A Tramontano,et al.  Substrate Specificity of the Hepatitis C Virus Serine Protease NS3* , 1997, The Journal of Biological Chemistry.

[20]  R. Bartenschlager,et al.  Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase , 1995, Journal of virology.

[21]  Motohiro Shibata,et al.  Detection of hepatitis C virus by polymerase chain reaction and response to interferon‐α therapy: Relationship to genotypes of hepatitis C virus , 1992, Hepatology.

[22]  A. Nomoto,et al.  Down-regulation of translation driven by hepatitis C virus internal ribosomal entry site by the 3′ untranslated region of RNA , 2001, Archives of Virology.