The role of C-terminal amino acid residues of a Δ⁶-fatty acid desaturase from blackcurrant.

[1]  Zan-min Hu,et al.  Identification and functional analysis of the genes encoding Δ6-desaturase from Ribes nigrum† , 2010, Journal of experimental botany.

[2]  Mingchun Li,et al.  Evolution-related amino acids play important role in determining regioselectivity of fatty acid desaturase from Pichia pastoris , 2009, Molecular Biology Reports.

[3]  G. Braus,et al.  A Small Membrane-peripheral Region Close to the Active Center Determines Regioselectivity of Membrane-bound Fatty Acid Desaturases from Aspergillus nidulans* , 2007, Journal of Biological Chemistry.

[4]  S. Cheevadhanarak,et al.  Targeted mutagenesis of a fatty acid Delta6-desaturase from Mucor rouxii: role of amino acid residues adjacent to histidine-rich motif II. , 2006, Biochemical and biophysical research communications.

[5]  P. Covello,et al.  Domain Swapping Localizes the Structural Determinants of Regioselectivity in Membrane-bound Fatty Acid Desaturases of Caenorhabditis elegans* , 2004, Journal of Biological Chemistry.

[6]  S. Cheevadhanarak,et al.  Mutation study of conserved amino acid residues of Spirulina Δ6-acyl-lipid desaturase showing involvement of histidine 313 in the regioselectivity of the enzyme , 2004, Applied Microbiology and Biotechnology.

[7]  Manabu T. Nakamura,et al.  STRUCTURE, FUNCTION, AND DIETARY REGULATION OF Δ6, Δ5, AND Δ9 DESATURASES , 2004 .

[8]  H. Guillou,et al.  Distinct roles of endoplasmic reticulum cytochrome b5 and fused cytochrome b5-like domain for rat Delta6-desaturase activity. , 2004, Journal of lipid research.

[9]  T. Zank,et al.  The evolution of desaturases. , 2003, Prostaglandins, leukotrienes, and essential fatty acids.

[10]  P. Shewry,et al.  Mutagenesis and heterologous expression in yeast of a plant Delta6-fatty acid desaturase. , 2001, Journal of experimental botany.

[11]  P. Shewry,et al.  Chimeras of Delta6-fatty acid and Delta8-sphingolipid desaturases. , 2000, Biochemical and biophysical research communications.

[12]  P. Shewry,et al.  Mutagenesis of the borage Δ6 fatty acid desaturase. , 2000 .

[13]  A. Oberhauser,et al.  Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering. , 2000, Progress in biophysics and molecular biology.

[14]  P. Shewry,et al.  Histidine-41 of the cytochrome b5 domain of the borage delta6 fatty acid desaturase is essential for enzyme activity. , 1999, Plant physiology.

[15]  P. Broun,et al.  Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. , 1998, Science.

[16]  P. Shewry,et al.  A new class of cytochrome b5 fusion proteins. , 1997, The Biochemical journal.