Concepts of Alzheimer Disease

As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.

[1]  J. Rowe The New Gerontology , 1997, Science.

[2]  J. Morrison,et al.  Life and death of neurons in the aging brain. , 1997, Science.

[3]  J. Haines,et al.  Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. , 1997, JAMA.

[4]  J. Trojanowski,et al.  Editorial on Consensus Recommendations for the Postmortem Diagnosis of Alzheimer Disease from the National Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer Disease , 1997, Journal of neuropathology and experimental neurology.

[5]  G. Schellenberg,et al.  Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease , 1997, Neurology.

[6]  John T. Bruer,et al.  Science Funding and Private Philanthropy , 1997, Science.

[7]  Alistair Burns,et al.  Observations on the brains of demented old people. B.E. Tomlinson, G. Blessed and M. Roth, Journal of the Neurological Sciences (1970) 11, 205–242; (1968) 7, 331–356 , 1997 .

[8]  Konrad Maurer,et al.  Auguste D and Alzheimer's disease , 1997, The Lancet.

[9]  H. Möller,et al.  Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis , 1997, Neurogenetics.

[10]  Melissa S. Anderson,et al.  Withholding research results in academic life science. Evidence from a national survey of faculty. , 1997, JAMA.

[11]  D. Dickson,et al.  The Pathogenesis of Senile Plaques , 1997, Journal of neuropathology and experimental neurology.

[12]  R. Henderson,et al.  Public-private interaction in pharmaceutical research. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[13]  L. Amaducci Alzheimer's original patient. , 1996, Science.

[14]  G. Meilaender Bioethics: A Primer for Christians , 1996 .

[15]  C. O'Brien Auguste D. and Alzheimer's Disease , 1996, Science.

[16]  A. A. Clair,et al.  Therapeutic Uses of Music with Older Adults , 1996 .

[17]  D Blumenthal,et al.  Relationships between academic institutions and industry in the life sciences--an industry survey. , 1996, The New England journal of medicine.

[18]  A. Handyside,et al.  Preimplantation genetic testing for Huntington disease and certain other dominantly inherited disorders , 1996, Clinical genetics.

[19]  H. Tristram Engelhardt,et al.  The Foundations of Bioethics , 1996 .

[20]  P. Whitehouse,et al.  Situated Beyond Modernity: Lessons for Alzheimer's Disease Research , 1995, Journal of the American Geriatrics Society.

[21]  J. Rommens,et al.  Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene , 1995, Nature.

[22]  W. Andrew Achenbaum,et al.  Crossing Frontiers: Gerontology Emerges as a Science. , 1995 .

[23]  G. Schellenberg,et al.  Candidate gene for the chromosome 1 familial Alzheimer's disease locus , 1995, Science.

[24]  D. Pollen,et al.  Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease , 1995, Nature.

[25]  E M Wijsman,et al.  Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease , 1995, Neurology.

[26]  E. Herskovits Struggling over subjectivity: debates about the "self" and Alzheimer's disease. , 1995, Medical anthropology quarterly.

[27]  E. Peskind,et al.  Suicide in Two Patients with Alzheimer's Disease , 1995, Journal of the American Geriatrics Society.

[28]  D. Selkoe,et al.  Alzheimer's Disease: A Central Role for Amyloid , 1994, Journal of neuropathology and experimental neurology.

[29]  J. Gusfield,et al.  New Social Movements: From Ideology to Identity , 1994 .

[30]  H. Blumenthal The Aging‐Disease Dichotomy Is Alive, but Is It Well? , 1993, Journal of the American Geriatrics Society.

[31]  D. Pollen Hannah's Heirs: The Quest for the Genetic Origins of Alzheimer's Disease , 1993 .

[32]  T. Cole,et al.  The Journey of Life: A Cultural History of Aging in America. , 1993 .

[33]  C. Rosenberg FRAMING DISEASE : ILLNESS, SOCIETY, AND HISTORY , 1992 .

[34]  J. Hardy,et al.  Alzheimer's disease: the amyloid cascade hypothesis. , 1992, Science.

[35]  M. A. Wachter Euthanasia in the Netherlands , 1992 .

[36]  Anson Rabinbach,et al.  The human motor : energy, fatigue, and the origins of modernity , 1992 .

[37]  J. Ulrich,et al.  Alzheimer's Disease: A Description of the Structural Lesions , 1991, Brain pathology.

[38]  James S. Goodwin Geriatric Ideology: The Myth of the Myth of Senility , 1991, Journal of the American Geriatrics Society.

[39]  A. Firlik Margo's Logo , 1991 .

[40]  G. Berríos,et al.  Alzheimer's disease: A conceptual history , 1990 .

[41]  P. Fox From senility to Alzheimer's disease: the rise of the Alzheimer's disease movement. , 1989, The Milbank quarterly.

[42]  M. Nicolson,et al.  Social constructionism and medical sociology: a study of the vascular theory of multiple sclerosis , 1988 .

[43]  L. Amaducci,et al.  The Early Story of Alzheimer's Disease , 1987 .

[44]  Myfanwy Thomas,et al.  Alois Alzheimer: A memoir , 1987, Trends in Neurosciences.

[45]  T. Beach,et al.  The history of Alzheimer's disease: three debates. , 1987, Journal of the history of medicine and allied sciences.

[46]  C. Schorer Historical Essay: Kraepelin's Description of Alzheimer's Disease , 1986, International journal of aging & human development.

[47]  J. Gubrium Oldtimers and Alzheimer's: The Descriptive Organization of Senility , 1986 .

[48]  H. Braak,et al.  Golgi preparations as a tool in neuropathology with particular reference to investigations of the human telencephalic cortex , 1985, Progress in Neurobiology.

[49]  Z. Khachaturian Diagnosis of Alzheimer's disease. , 1985, Archives of neurology.

[50]  P. Whitehouse Theodor Meynert , 1985, Neurology.

[51]  I. Sawhill,et al.  The Reagan Record. , 1985 .

[52]  J. Coyle,et al.  Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. , 1982, Science.

[53]  S. Schneck,et al.  Twins with Alzheimer's disease. , 1981, Archives of neurology.

[54]  Prof. Dr. Heiko Braak,et al.  Architectonics of the Human Telencephalic Cortex , 1980, Studies of Brain Function.

[55]  D. Botstein,et al.  Construction of a genetic linkage map in man using restriction fragment length polymorphisms. , 1980, American journal of human genetics.

[56]  E K Perry,et al.  Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. , 1978, British medical journal.

[57]  Christopher Boorse,et al.  Health as a Theoretical Concept , 1977, Philosophy of Science.

[58]  G. Stevenson,et al.  The Health Care Industry in Advanced Capitalism , 1977 .

[59]  R. Katzman.,et al.  Editorial: The prevalence and malignancy of Alzheimer disease. A major killer. , 1976, Archives of neurology.

[60]  I. Farber Sane and insane: constructions and misconstructions. , 1975, Journal of abnormal psychology.

[61]  S. Crown "On being sane in insane places": a comment from England. , 1975, Journal of abnormal psychology.

[62]  B. Weiner "On being sane in insane places": a process (attributional) analysis and critique. , 1975, Journal of abnormal psychology.

[63]  R. Spitzer On pseudoscience in science, logic in remission, and psychiatric diagnosis: a critique of Rosenhan's "On being sane in insane places". , 1975, Journal of abnormal psychology.

[64]  N. Lassen,et al.  Multi-infarct dementia. A cause of mental deterioration in the elderly. , 1974, Lancet.

[65]  D. Rosenhan On being sane in insane places , 1973, Science.

[66]  J A Deutsch,et al.  The Cholinergic Synapse and the Site of Memory , 1971, Science.

[67]  M. Roth,et al.  The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects , 1968, British Journal of Psychiatry.

[68]  R. Tissot,et al.  [Various aspects of the speech of degenerative dementia in old age]. , 1967, Acta neurologica et psychiatrica Belgica.

[69]  Wallington Ea The explosive properties of ammoniacal-silver solutions. , 1965 .

[70]  R. Friede Enzyme Histochemical Studies of Senile Plaques , 1965 .

[71]  R. Terry,et al.  ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA. , 1964, The American journal of pathology.

[72]  T. Rudd PREVENTING SENILE DEMENTIA: THE NEED FOR A NEW APPROACH , 1959, Journal of the American Geriatrics Society.

[73]  M. Roth The natural history of mental disorder in old age. , 1955, The Journal of mental science.

[74]  R. Newton The identity of Alzheimer's disease and sinile dementia and their relationship to senility. , 1948, The Journal of mental science.

[75]  A. Wc Cerebral arteriosclerosis, with small, commonly unrecognized apoplexies. , 1946 .

[76]  K. Stern,et al.  The Treatment, Pathology and Prevention of Mental Disorders in the Aged. , 1942, Canadian Medical Association journal.

[77]  Johannes Schottky Über präsenile Verblödungen , 1932 .

[78]  A. Ferraro THE ORIGIN AND FORMATION OF SENILE PLAQUES , 1931 .

[79]  F. Flügel Zur Diagnostik der Alzheimerschen Krankheit , 1929 .

[80]  E. Grünthal Klinisch-anatomisch vergleichende Untersuchungen über den Greisenblödsinn , 1927 .

[81]  G. Mingazzini ON APHASIA DUE TO ATROPHY OF THE CEREBRAL CONVOLUTIONS , 1914 .

[82]  S. C. Fuller ALZHEIMER'S DISEASE (SENIUM PRÆCOX): THE REPORT OF A CASE AND REVIEW OF PUBLISHED CASES , 1912 .

[83]  E. Southard ANATOMICAL FINDINGS IN SENILE DEMENTIA: A DIAGNOSTIC STUDY BEARING ESPECIALLY ON THE GROUP OF CEREBRAL ATROPHIES , 1910 .

[84]  William P. Pickett SENILE DEMENTIA; A CLINICAL STUDY OF TWO HUNDRED CASES WITH PARTICULAR REGARD TO TYPES OF THE DISEASE , 1904 .

[85]  Doug McAdam,et al.  Culture and Social Movements , 2000 .

[86]  K. Maurer,et al.  Alzheimer : das Leben eines Arztes und die Karriere einer Krankheit , 1998 .

[87]  R Nieuwenhuys,et al.  The greater limbic system, the emotional motor system and the brain. , 1996, Progress in brain research.

[88]  S. Post The Moral Challenge of Alzheimer Disease , 1995 .

[89]  Daniel T. O'Connor,et al.  Dementia and normal aging , 1994 .

[90]  L. Fratiglioni,et al.  Alcohol and tobacco consumption as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group. , 1991, International journal of epidemiology.

[91]  J. G. Evans Ageing and disease. , 1988, Ciba Foundation symposium.

[92]  B. Latour Science in Action , 1987 .

[93]  J. W. Reed,et al.  No Magic Bullet: A Social History of Veneral Disease in the United States since 1880 , 1986 .

[94]  Betty A. Lockett,et al.  Aging, politics, and research : setting the federal agenda for research on aging , 1983 .

[95]  S P Strickland,et al.  Politics, science, and dread disease. , 1975, Transactions & studies of the College of Physicians of Philadelphia.

[96]  H. Tristram Engelhardt,et al.  The Concepts of Health and Disease , 1975 .

[97]  M. Roth,et al.  The diagnosis of dementia. , 1975, The British journal of psychiatry : the journal of mental science.

[98]  J. Feighner,et al.  Diagnostic criteria for use in psychiatric research. , 1972, Archives of general psychiatry.

[99]  G. Hardin,et al.  The Tragedy of the Commons , 1968, Green Planet Blues.

[100]  Daniel S. Greenberg,et al.  The politics of pure science , 1967 .

[101]  M. Roth,et al.  Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects , 1966, Nature.

[102]  F. W. Bronisch Hirnatrophische Prozesse im mittleren Lebensalter und ihre psychischen Erscheinungsbilder , 1951 .

[103]  A. Lewis Ageing and senility; a major problem of psychiatry. , 1946, The Journal of mental science.

[104]  M. Battin Euthanasia in alzheimer's disease? , 1933 .

[105]  A. S. Warthin Old age : the major involution : the physiology & pathology of the aging process , 1929 .

[106]  E. Bleuler Lehrbuch der Psychiatrie , 1918 .

[107]  F. Lewy Paralysis agitans. I. Pathologische Anatomie , 1912 .

[108]  E. Kraepelin Psychiatrie : ein Lehrbuch für Studi[e]rende und Aerzte , 1976 .

[109]  C. Weigert Beiträge zur Kenntnis der normalen menschlichen Neuroglia : Festschrift zum fünfzigjährigen Jubiläum des ärztlichen Vereins zu Frankfurt a. M., 3. November 1895 , 1895 .